University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Gideon St. Helen, PhD

Gideon St. Helen, PhD

Assistant Professor, Department of Medicine, UCSF

Cancer Center Program Memberships

Tobacco Control

Education

Livingstone College, Salisbury, NC, B.S., 05/2006, Biology
University of Georgia, Athens, GA, Ph.D., 08/2011, Toxicology
University of California, San Francisco, CA, Postdoc, 12/2014, Tobacco Control and Research


Professional Experience

  • 2015-present
    Assistant Professor, Department of Medicine, University of California, San Francisco, CA

Honors & Awards

  • 2003-2006
    Academic Gold Medal, Livingstone College
  • 2006
    Summer Bridge Fellow, University of Georgia
  • 2012
    Society for Research on Nicotine and Tobacco Travel Award
  • 2012
    Centers for Disease Control and Prevention (CDC) Top-Ten Research Article

Selected Publications

  1. Havel CM, Benowitz NL, Jacob P, St Helen G. An Electronic Cigarette Vaping Machine for the Characterization of Aerosol Delivery and Composition. Nicotine Tob Res. 2017 Oct 01; 19(10):1224-1231.
    View on PubMed
  2. St Helen G, Dempsey DA, Havel CM, Jacob P, Benowitz NL. Impact of e-liquid flavors on nicotine intake and pharmacology of e-cigarettes. Drug Alcohol Depend. 2017 Sep 01; 178:391-398.
    View on PubMed
  3. Schick SF, Blount BC, Jacob P, Saliba NA, Bernert JT, El Hellani A, Jatlow P, Pappas RS, Wang L, Foulds J, Ghosh A, Hecht SS, Gomez JC, Martin JR, Mesaros C, Srivastava S, St Helen G, Tarran R, Lorkiewicz PK, Blair IA, Kimmel HL, Doerschuk CM, Benowitz NL, Bhatnagar A. Biomarkers of exposure to new and emerging tobacco delivery products. Am J Physiol Lung Cell Mol Physiol. 2017 Sep 01; 313(3):L425-L452.
    View on PubMed
  4. Taghavi T, St Helen G, Benowitz NL, Tyndale RF. Effect of UGT2B10, UGT2B17, FMO3, and OCT2 genetic variation on nicotine and cotinine pharmacokinetics and smoking in African Americans. Pharmacogenet Genomics. 2017 Apr; 27(4):143-154.
    View on PubMed
  5. Benowitz NL, Jain S, Dempsey DA, Nardone N, St Helen G, Jacob P. Urine Cotinine Screening Detect Nearly Ubiquitous Tobacco Smoke Exposure in Urban Adolescents. Nicotine Tob Res. 2016 Dec 28.
    View on PubMed
  6. St Helen G, Ross KC, Dempsey DA, Havel CM, Jacob P, Benowitz NL. Nicotine Delivery and Vaping Behavior During ad Libitum E-cigarette Access. Tob Regul Sci. 2016 Oct; 2(4):363-376.
    View on PubMed
  7. Benowitz NL, St Helen G, Dempsey DA, Jacob P, Tyndale RF. Disposition kinetics and metabolism of nicotine and cotinine in African American smokers: impact of CYP2A6 genetic variation and enzymatic activity. Pharmacogenet Genomics. 2016 07; 26(7):340-50.
    View on PubMed
  8. Ross KC, Dempsey DA, St Helen G, Delucchi K, Benowitz NL. The Influence of Puff Characteristics, Nicotine Dependence, and Rate of Nicotine Metabolism on Daily Nicotine Exposure in African American Smokers. Cancer Epidemiol Biomarkers Prev. 2016 Jun; 25(6):936-43.
    View on PubMed
  9. St Helen G, Havel C, Dempsey DA, Jacob P, Benowitz NL. Nicotine delivery, retention and pharmacokinetics from various electronic cigarettes. Addiction. 2016 Mar; 111(3):535-44.
    View on PubMed
  10. St Helen G, Aguilar-Villalobos M, Adetona O, Cassidy B, Bayer CW, Hendry R, Hall DB, Naeher LP. Exposure of pregnant women to cookstove-related household air pollution in urban and periurban Trujillo, Peru. Arch Environ Occup Health. 2015; 70(1):10-8.
    View on PubMed
  11. St Helen G, Jacob P, Peng M, Dempsey DA, Hammond SK, Benowitz NL. Intake of toxic and carcinogenic volatile organic compounds from secondhand smoke in motor vehicles. Cancer Epidemiol Biomarkers Prev. 2014 Dec; 23(12):2774-82.
    View on PubMed
  12. St Helen G, Benowitz NL, Dains KM, Havel C, Peng M, Jacob P. Nicotine and carcinogen exposure after water pipe smoking in hookah bars. Cancer Epidemiol Biomarkers Prev. 2014 Jun; 23(6):1055-66.
    View on PubMed
  13. Dempsey DA, St Helen G, Jacob P, Tyndale RF, Benowitz NL. Genetic and pharmacokinetic determinants of response to transdermal nicotine in white, black, and Asian nonsmokers. Clin Pharmacol Ther. 2013 Dec; 94(6):687-94.
    View on PubMed
  14. St Helen G, Jacob P, Benowitz NL. Stability of the nicotine metabolite ratio in smokers of progressively reduced nicotine content cigarettes. Nicotine Tob Res. 2013 Nov; 15(11):1939-42.
    View on PubMed
  15. Jones IA, St Helen G, Meyers MJ, Dempsey DA, Havel C, Jacob P, Northcross A, Hammond SK, Benowitz NL. Biomarkers of secondhand smoke exposure in automobiles. Tob Control. 2014 Jan; 23(1):51-7.
    View on PubMed
  16. Benowitz NL, Dempsey D, Tyndale RF, St Helen G, Jacob P. Dose-independent kinetics with low level exposure to nicotine and cotinine. Br J Clin Pharmacol. 2013 Jan; 75(1):277-9.
    View on PubMed
  17. St Helen G, Dempsey D, Wilson M, Jacob P, Benowitz NL. Racial differences in the relationship between tobacco dependence and nicotine and carcinogen exposure. Addiction. 2013 Mar; 108(3):607-17.
    View on PubMed
  18. St Helen G, Holland NT, Balmes JR, Hall DB, Bernert JT, Vena JE, Wang JS, Naeher LP. Utility of urinary Clara cell protein (CC16) to demonstrate increased lung epithelial permeability in non-smokers exposed to outdoor secondhand smoke. J Expo Sci Environ Epidemiol. 2013 Mar; 23(2):183-9.
    View on PubMed
  19. St Helen G, Novalen M, Heitjan DF, Dempsey D, Jacob P, Aziziyeh A, Wing VC, George TP, Tyndale RF, Benowitz NL. Reproducibility of the nicotine metabolite ratio in cigarette smokers. Cancer Epidemiol Biomarkers Prev. 2012 Jul; 21(7):1105-14.
    View on PubMed
  20. St Helen G, Bernert JT, Hall DB, Sosnoff CS, Xia Y, Balmes JR, Vena JE, Wang JS, Holland NT, Naeher LP. Exposure to secondhand smoke outside of a bar and a restaurant and tobacco exposure biomarkers in nonsmokers. Environ Health Perspect. 2012 Jul; 120(7):1010-6.
    View on PubMed

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