Bradley A. Stohr, MD, PhD

Bradley A. Stohr, MD, PhD

Assistant Professor, Department of Pathology, UCSF

Phone: (415) 476-6729
Box 0502, UCSF
San Francisco, CA 94143-0502

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Cancer Center Membership

Associate Member » Non-aligned


Swarthmore College, Swarthmore, PA, BA, 1995, Biology
Duke University, Durham, NC, PhD, 2002, Microbiology
Duke University, Durham, NC, MD, 2003, Medicine
University of California, San Francisco, CA, Resident/Fellow, 2003-2006, Anatomic Pathology
University of California, San Francisco, CA, Postdoctoral Fellow, 2005-2008, Biochemistry

Professional Experience

  • 1993-1994
    Research Assistant, Jackson Laboratory. Advisor: Sandya Narayanswami, Ph.D.
  • 1995-1996
    Research Assistant, Department of Microbiology, University of California, Davis. Advisor: Satya Dandekar, Ph.D.
  • 1998-2002
    Graduate Student, Department of Microbiology, Duke University Advisor: Kenneth Kreuzer, Ph.D.
  • 2003-2006
    Resident/Fellow, Anatomic Pathology, University of California, San Francisco
  • 2005-2008
    Postdoctoral Fellow, Department of Biochemistry, University of California, San Francisco Advisor: Elizabeth Blackburn, Ph.D.
  • 2008-2010
    Clinical Instructor, Department of Pathology, University of California, San Francisco

Honors & Awards

  • 1995
    Phi Beta Kappa honor society
  • 1995
    Sigma Xi honor society
  • 1996-2003
    Medical Scientist Training Program Fellowship
  • 2005
    Ruth L. Kirschstein Postdoctoral Fellowship (declined)
  • 2005-2008
    American Cancer Society Postdoctoral Fellowship
  • 2010-present
    Mentored Clinical Scientist Development Award (K08)

Selected Publications

  1. Barfoot T, Herdendorf TJ, Behning BR, Stohr BA, Gao Y, Kreuzer KN, Nelson SW. Functional Analysis of the Bacteriophage T4 Rad50 Homolog (gp46) Coiled-coil Domain. J Biol Chem. 2015 Sep 25; 290(39):23905-15.
    View on PubMed
  2. Frank AK, Tran DC, Qu RW, Stohr BA, Segal DJ, Xu L. The Shelterin TIN2 Subunit Mediates Recruitment of Telomerase to Telomeres. PLoS Genet. 2015 Jul; 11(7):e1005410.
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  3. Mar FA, Debnath J, Stohr BA. Autophagy-independent senescence and genome instability driven by targeted telomere dysfunction. Autophagy. 2015 Mar 4; 11(3):527-37.
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  4. Flach J, Bakker ST, Mohrin M, Conroy PC, Pietras EM, Reynaud D, Alvarez S, Diolaiti ME, Ugarte F, Forsberg EC, Le Beau MM, Stohr BA, Méndez J, Morrison CG, Passegué E. Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells. Nature. 2014 Aug 14; 512(7513):198-202.
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  5. Almond JR, Stohr BA, Panigrahi AK, Albrecht DW, Nelson SW, Kreuzer KN. Coordination and processing of DNA ends during double-strand break repair: the role of the bacteriophage T4 Mre11/Rad50 (MR) complex. Genetics. 2013 Nov; 195(3):739-55.
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  6. Diolaiti ME, Cimini BA, Kageyama R, Charles FA, Stohr BA. In situ visualization of telomere elongation patterns in human cells. Nucleic Acids Res. 2013 Oct; 41(18):e176.
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  7. Xu L, Li S, Stohr BA. The role of telomere biology in cancer. Annu Rev Pathol. 2013 Jan 24; 8:49-78.
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  8. Vergara-Lluri ME, Stohr BA, Puligandla B, Brenholz P, Horvai AE. A novel sarcoma with dual differentiation: clinicopathologic and molecular characterization of a combined synovial sarcoma and extraskeletal myxoid chondrosarcoma. Am J Surg Pathol. 2012 Jul; 36(7):1093-8.
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  9. Stohr BA, Xu L, Blackburn EH. The terminal telomeric DNA sequence determines the mechanism of dysfunctional telomere fusion. Mol Cell. 2010 Jul 30; 39(2):307-14.
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  10. Stohr BA, Blackburn EH. ATM mediates cytotoxicity of a mutant telomerase RNA in human cancer cells. Cancer Res. 2008 Jul 1; 68(13):5309-17.
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  11. Stohr BA, Kreuzer KN. Coordination of DNA ends during double-strand-break repair in bacteriophage T4. Genetics. 2002 Nov; 162(3):1019-30.
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  12. George JW, Stohr BA, Tomso DJ, Kreuzer KN. The tight linkage between DNA replication and double-strand break repair in bacteriophage T4. Proc Natl Acad Sci U S A. 2001 Jul 17; 98(15):8290-7.
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  13. Stohr BA, Kreuzer KN. Repair of topoisomerase-mediated DNA damage in bacteriophage T4. Genetics. 2001 May; 158(1):19-28.
    View on PubMed

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