Bradley A. Stohr, MD, PhD

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Bradley A. Stohr, MD, PhD

Assistant Professor, Department of Pathology, UCSF

bradley.stohr@ucsf.edu

Phone: (415) 476-6729
Box 0502, UCSF
San Francisco, CA 94143-0502

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Cancer Center Membership

Associate Member ยป Non-aligned

Education

Swarthmore College, Swarthmore, PA, BA, 1995, Biology
Duke University, Durham, NC, PhD, 2002, Microbiology
Duke University, Durham, NC, MD, 2003, Medicine
University of California, San Francisco, CA, Resident/Fellow, 2003-2006, Anatomic Pathology
University of California, San Francisco, CA, Postdoctoral Fellow, 2005-2008, Biochemistry


Professional Experience

  • 1993-1994
    Research Assistant, Jackson Laboratory. Advisor: Sandya Narayanswami, Ph.D.
  • 1995-1996
    Research Assistant, Department of Microbiology, University of California, Davis. Advisor: Satya Dandekar, Ph.D.
  • 1998-2002
    Graduate Student, Department of Microbiology, Duke University Advisor: Kenneth Kreuzer, Ph.D.
  • 2003-2006
    Resident/Fellow, Anatomic Pathology, University of California, San Francisco
  • 2005-2008
    Postdoctoral Fellow, Department of Biochemistry, University of California, San Francisco Advisor: Elizabeth Blackburn, Ph.D.
  • 2008-2010
    Clinical Instructor, Department of Pathology, University of California, San Francisco

Honors & Awards

  • 1995
    Phi Beta Kappa honor society
  • 1995
    Sigma Xi honor society
  • 1996-2003
    Medical Scientist Training Program Fellowship
  • 2005
    Ruth L. Kirschstein Postdoctoral Fellowship (declined)
  • 2005-2008
    American Cancer Society Postdoctoral Fellowship
  • 2010-present
    Mentored Clinical Scientist Development Award (K08)

Selected Publications

  1. Functional Analysis of the Bacteriophage T4 Rad50 Homolog (gp46) Coiled-coil Domain. J Biol Chem. 2015 Sep 25; 290(39):23905-15.
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  2. The Shelterin TIN2 Subunit Mediates Recruitment of Telomerase to Telomeres. PLoS Genet. 2015 Jul; 11(7):e1005410.
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  3. Autophagy-independent senescence and genome instability driven by targeted telomere dysfunction. Autophagy. 2015 Mar 4; 11(3):527-37.
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  4. Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells. Nature. 2014 Aug 14; 512(7513):198-202.
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  5. Coordination and processing of DNA ends during double-strand break repair: the role of the bacteriophage T4 Mre11/Rad50 (MR) complex. Genetics. 2013 Nov; 195(3):739-55.
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  6. In situ visualization of telomere elongation patterns in human cells. Nucleic Acids Res. 2013 Oct; 41(18):e176.
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  7. The role of telomere biology in cancer. Annu Rev Pathol. 2013 Jan 24; 8:49-78.
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  8. A novel sarcoma with dual differentiation: clinicopathologic and molecular characterization of a combined synovial sarcoma and extraskeletal myxoid chondrosarcoma. Am J Surg Pathol. 2012 Jul; 36(7):1093-8.
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  9. The terminal telomeric DNA sequence determines the mechanism of dysfunctional telomere fusion. Mol Cell. 2010 Jul 30; 39(2):307-14.
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  10. ATM mediates cytotoxicity of a mutant telomerase RNA in human cancer cells. Cancer Res. 2008 Jul 1; 68(13):5309-17.
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  11. Coordination of DNA ends during double-strand-break repair in bacteriophage T4. Genetics. 2002 Nov; 162(3):1019-30.
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  12. The tight linkage between DNA replication and double-strand break repair in bacteriophage T4. Proc Natl Acad Sci U S A. 2001 Jul 17; 98(15):8290-7.
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  13. Repair of topoisomerase-mediated DNA damage in bacteriophage T4. Genetics. 2001 May; 158(1):19-28.
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