University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Jonathan P. Terdiman, MD

Jonathan P. Terdiman, MD

Associate Clinical Professor, Department of Medicine (Gastroenterology), UCSF

Cancer Center Program Memberships

Affiliate Member

Research Summary

Dr. Jonathan P. Terdiman is a Professor of Clinical Medicine and Surgery and the Chief of the Gastroenterology Division at UCSF. He earned his undergraduate degree from Princeton University in 1985 and his medical degree from the Columbia University College of Physicians and Surgeons in 1989. Dr. Terdiman completed his internal medicine residency and fellowships in both critical care medicine and gastroenterology at UCSF before joining the faculty in 1996.

Dr. Terdiman has a busy clinical practice in gastroenterology, with a focus on the management of patients with inflammatory bowel disease. In 2013 Dr Terdiman was elected to the UCSF Department of Medicine’s Master Clinician Council. Dr Terdiman has been named a Bay area Top Doctor by San Francisco Magazine for the past four years and counting. Dr Terdiman also is a leading teacher of clinical medicine. He has received numerous campus-wide teaching awards, and he is a past member of the Haile T Debas Academy of Medical Educators.

Dr. Terdiman’s primary research activities focus on the assessment and mitigation of the risk among patients and families with a genetic predisposition to gastrointestinal cancers. He also is actively engaged in projects assessing the safety and efficacy of new therapies for inflammatory bowel disease. Dr. Terdiman chairs the American Gastroenterological Association guideline panel on the proper use of immune modulators and biological drugs in the treatment of moderate to severe Crohn’s disease, and he is the senior author of a new AGA technical review on the management of moderate to severe ulcerative colitis .

In addition to his work at UCSF, Dr Terdiman has served on the board of trustees of the Northern California Chapter of the Crohn’s and Colitis Foundation of America (CCFA) for many years, and was board president from 2010-2012. In 2012 the chapter named Dr. Terdiman as a CCFA Champion of Hope. Dr Terdiman also is a member of the board of trustees of the Brandeis School of San Francisco.

Education

Princeton University, A.B., cum laude, 1985
Columbia University, College of Physicians and Surgeons, M.D., 1989

Honors & Awards

  • 2000
    UCSF Medical School Class of 2002, Excellence in Small Group Instruction, recipient
  • 2002
    UCSF Medical School Class of 2004, Excellence in Small Group Instruction, recipient
  • 2004
    UCSF Medical School Class of 2006, Excellence in Small Group Instruction, recipient
  • 2005
    Excellence in Direct Teaching, recipient, UCSF Academy of Medical Educators

Selected Publications

  1. Provenzale D, Ness RM, Llor X, Weiss JM, Abbadessa B, Cooper G, Early DS, Friedman M, Giardiello FM, Glaser K, Gurudu S, Halverson AL, Issaka R, Jain R, Kanth P, Kidambi T, Lazenby AJ, Maguire L, Markowitz AJ, May FP, Mayer RJ, Mehta S, Patel S, Peter S, P Stanich P, Terdiman J, Keller J, Dwyer MA, Ogba N. NCCN Guidelines Insights: Colorectal Cancer Screening, Version 2.2020. J Natl Compr Canc Netw. 2020 10 01; 18(10):1312-1320.
    View on PubMed
  2. Kotwani P, Terdiman J, Lewin S. Tofacitinib for Rescue Therapy in Acute Severe Ulcerative Colitis: A Real-world Experience. J Crohns Colitis. 2020 Jul 30; 14(7):1026-1028.
    View on PubMed
  3. Lee JK, Kidambi TD, Kaltenbach T, Bhat YM, Shergill A, McQuaid KR, Terdiman JP, Soetikno RM. Impact of observational training on endoscopic mucosal resection outcomes and competency for large colorectal polyps: single endoscopist experience. Endosc Int Open. 2020 Mar; 8(3):E346-E353.
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  4. Singh S, Allegretti JR, Siddique SM, Terdiman JP. AGA Technical Review on the Management of Moderate to Severe Ulcerative Colitis. Gastroenterology. 2020 04; 158(5):1465-1496.e17.
    View on PubMed
  5. Selvig D, Piceno Y, Terdiman J, Zydek M, Umetsu SE, Balitzer D, Fadrosh D, Lynch K, Lamere B, Leith T, Kassam Z, Beck K, Lewin S, Ma A, Somsouk M, Lynch SV, El-Nachef N. Fecal Microbiota Transplantation in Pouchitis: Clinical, Endoscopic, Histologic, and Microbiota Results from a Pilot Study. Dig Dis Sci. 2020 04; 65(4):1099-1106.
    View on PubMed
  6. Gutin L, Piceno Y, Fadrosh D, Lynch K, Zydek M, Kassam Z, LaMere B, Terdiman J, Ma A, Somsouk M, Lynch S, El-Nachef N. Fecal microbiota transplant for Crohn disease: A study evaluating safety, efficacy, and microbiome profile. United European Gastroenterol J. 2019 07; 7(6):807-814.
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  7. Adler E, Tabaa A, Kassam Z, Zydek M, Terdiman J, El-Nachef N. Capsule-Delivered Fecal Microbiota Transplant Is Safe and Well Tolerated in Patients with Ulcerative Colitis. Dig Dis Sci. 2019 09; 64(9):2452-2454.
    View on PubMed
  8. Mao EJ, Lewin S, Terdiman JP, Beck K. Safety of dual biological therapy in Crohn's disease: a case series of vedolizumab in combination with other biologics. BMJ Open Gastroenterol. 2018; 5(1):e000243.
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  9. Kidambi TD, Terdiman JP, Lee JK. Negative withdrawal time: simple and efficient. Gastrointest Endosc. 2018 10; 88(4):781.
    View on PubMed
  10. Kidambi TD, Terdiman JP, El-Nachef N, Singh A, Kattah MG, Lee JK. Effect of I-scan Electronic Chromoendoscopy on Detection of Adenomas During Colonoscopy. Clin Gastroenterol Hepatol. 2019 03; 17(4):701-708.e1.
    View on PubMed
  11. Kidambi TD, Goldberg D, Nussbaum R, Blanco A, Umetsu SE, Terdiman JP, Lee JK. Novel variant of unknown significance in MUTYH in a patient with MUTYH-associated polyposis: a case to reclassify. Clin J Gastroenterol. 2018 Dec; 11(6):457-460.
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  12. Gray PN, Tsai P, Chen D, Wu S, Hoo J, Mu W, Li B, Vuong H, Lu HM, Batth N, Willett S, Uyeda L, Shah S, Gau CL, Umali M, Espenschied C, Janicek M, Brown S, Margileth D, Dobrea L, Wagman L, Rana H, Hall MJ, Ross T, Terdiman J, Cullinane C, Ries S, Totten E, Elliott AM. TumorNext-Lynch-MMR: a comprehensive next generation sequencing assay for the detection of germline and somatic mutations in genes associated with mismatch repair deficiency and Lynch syndrome. Oncotarget. 2018 Apr 17; 9(29):20304-20322.
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  13. Kidambi TD, Pedley C, Blanco A, Bergsland EK, Terdiman JP. Lower gastrointestinal neuroendocrine neoplasms associated with hereditary cancer syndromes: a case series. Fam Cancer. 2017 10; 16(4):537-543.
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  14. Kidambi TD, Schmajuk G, Gross AJ, Ostroff JW, Terdiman JP, Lee JK. Endoscopy is of low yield in the identification of gastrointestinal neoplasia in patients with dermatomyositis: A cross-sectional study. World J Gastroenterol. 2017 Jul 14; 23(26):4788-4795.
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  15. Azofra AS, Kidambi TD, Jeremy RJ, Conrad P, Blanco A, Myers M, Barkovich J, Terdiman JP. Differences in neuropsychological and behavioral parameters and brain structure in patients with familial adenomatous polyposis: a sibling-paired study. Hered Cancer Clin Pract. 2016; 14:20.
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  16. Kidambi TD, Lee R, Terdiman JP, Day L. Successful implementation of Lynch syndrome screening in a safety net institution. J Community Genet. 2016 Jul; 7(3):255-60.
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  17. Kidambi TD, Blanco A, Van Ziffle J, Terdiman JP. Constitutional MLH1 methylation presenting with colonic polyposis syndrome and not Lynch syndrome. Fam Cancer. 2016 Apr; 15(2):275-80.
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  18. Guindalini RS, Win AK, Gulden C, Lindor NM, Newcomb PA, Haile RW, Raymond V, Stoffel E, Hall M, Llor X, Ukaegbu CI, Solomon I, Weitzel J, Kalady M, Blanco A, Terdiman J, Shuttlesworth GA, Lynch PM, Hampel H, Lynch HT, Jenkins MA, Olopade OI, Kupfer SS. Mutation spectrum and risk of colorectal cancer in African American families with Lynch syndrome. Gastroenterology. 2015 Nov; 149(6):1446-53.
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  19. Ho CK, Boscardin CK, Gleason N, Collado D, Terdiman J, Terrault NA, Gonzales R. Optimizing the pre-referral workup for gastroenterology and hepatology specialty care: consensus using the Delphi method. J Eval Clin Pract. 2016 Feb; 22(1):46-52.
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  20. Goodenberger ML, Thomas BC, Riegert-Johnson D, Boland CR, Plon SE, Clendenning M, Win AK, Senter L, Lipkin SM, Stadler ZK, Macrae FA, Lynch HT, Weitzel JN, de la Chapelle A, Syngal S, Lynch P, Parry S, Jenkins MA, Gallinger S, Holter S, Aronson M, Newcomb PA, Burnett T, Le Marchand L, Pichurin P, Hampel H, Terdiman JP, Lu KH, Thibodeau S, Lindor NM. PMS2 monoallelic mutation carriers: the known unknown. Genet Med. 2016 Jan; 18(1):13-9.
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