Daniel B. Vigneron, PhD

Daniel B. Vigneron, PhD

Professor, Department of Radiology & Biomedical Imaging, UCSF
Director, Hyperpolarized MRI Technology Resource Center


Phone: (415) 476-3343 (voice)
Box 2512, UCSF
San Francisco, CA 94158

Cancer Center Membership

Program Member » Prostate Cancer


Wesleyan University, Middletown, CT, BA, 1983, Chemistry/Pre-Med
University of California San Francisco, CA, PhD, 1988, Pharm. Chemistry
Fox Chase Cancer Center, Philadelphia, PA, Postdoctoral, 1988-90, Medical NMR

Professional Experience

  • 1988-1990
    Postdoctoral Research Associate, Dept. of NMR, Fox Chase Cancer Center, Philadelphia PA
  • 1990-1991
    Postdoctoral Research Fellow, Dept of Radiology, University of California, San Francisco
  • 1992-1997
    Assistant Professor, Department of Radiology, University of California, San Francisco
  • 1997- 2003
    Associate Professor, Department of Radiology, University of California, San Francisco
  • 2003-present
    Professor, Department of Radiology & Biomedical Imaging, University of California, San Francisco
  • 2007-present
    Director, MRI Specialized Research Group, Department of Radiology and Biomedical Imaging, University of California, San Francisco
  • 2008-present
    Professor, Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco

Honors & Awards

  • 1998-2000
    Three CapCure Foundation Research Awards
  • 2001
    American Society of Neuroradiology - Outstanding Presentation Award in Pediatric Neuroradiology
  • 2007
    American Society of Neuroradiology – Outstanding Presentation Award
  • 2007
    Elected to the College of Fellows of the American Institute for Medical and Biological Engineering
  • 2009
    International Society of Magnetic Resonance in Medicine Fellowship Award

Selected Publications

  • Cunningham CH, Chen AP, Albers MJ, Kurhanewicz J, Hurd RE, Yen Y-F, Pauly JM, Nelson SJ, Vigneron DB. Double Spin Echo Sequence For Rapid Spectroscopic Imaging of Hyperpolarized 13C. J. Magn Reson. 2007; 187:357-362.
  • Chen AP, Albers MJ, Cunningham CH, Kohler SJ, Yen Y, Hurd RE, Tropp J, Bok R, Pauly JM, Nelson SJ, Kurhanewicz J, Vigneron DB. High-Resolution Hyperpolarized C-13 Spectroscopic Imaging of the TRAMP mouse at 3T – Initial Experience. Magn. Reson. Med. 2007; 58:1099-1106.
  • Chen AP, Kurhanewicz J, Bok R, Xu D, Joun D, Zhang V, Nelson SJ, Hurd RE, Vigneron DB. Feasibility of Using Hyperpolarized [l-13C]Lactate as a Substrate for In Vivo Metabolic 13C MRSI Studies. Magn. Reson. Imag. 2008; 26(6):721-6. PMCID: PMC2577896
  • Chen AP, Tropp J, Hurd RE, Criekinge MV, Carvajal LG, Xu D, Kurhanewicz J, Vigneron DB. In vivo hyperpolarized (13)C MR spectroscopic imaging with (1)H decoupling. J Magn Reson. 2009; 197:100-6. PMCID: PMC2745403
  • Kurhanewicz J, Bok R, Nelson SJ, Vigneron DB. The Current and Potential Applications of Clinical 13C Magnetic Resonance Spectroscopy, J. Nucl. Med. 2008; 49:341-344. PMCID: PMC2832218
  • Cunningham CH, Chen AP, Lustig M, Lupo J, Xu D, Kurhanewicz J, Hurd RE, Pauly JM, Nelson SJ, Vigneron DB. Pulse Sequence for Dynamic Volumetric Imaging of Hyperpolarized Metabolic Products. J. Magn. Reson. 2008; 193(1):139-46. PMCID: PMC3051833
  • Hu S, Lustig M, Chen AP, Crane J, Kerr A, Kelley DAC, Hurd RE, Kurhanewicz J, Nelson SJ, Pauly JM, Vigneron DB. Compressed Sensing for Resolution Enhancement of Hyperpolarized 13C Flyback 3D-MRSI. J. Magn Reson. 2008; 192:258-264. PMCID: PMC2475338
  • Larson PEZ, Kerr AB, Chen AP, Lustig MS, Zierhut ML, Hu S, Cunningham CH, Pauly JM, Kurhanewicz J, Vigneron DB. Multiband Excitation Pulses for Hyperpolarized 13C Dynamic Chemical Shift Imaging. J. Magn. Reson. 2008; 194(1):121-127. NIHMS68214
  • Kurhanewicz J, Vigneron D, Carroll P, Coakley F. Multiparametric magnetic resonance imaging in prostate cancer: present and future. Curr Opin Urol. 2008; 18(1):71-7. PMCID: PMC2804482
  • Hu S, Lustig M, Balakrishnan A, Larson PE, Bok R, Kurhanewicz J, Nelson SJ, Goga A, Pauly JM, Vigneron DB. 3D compressed sensing for highly accelerated hyperpolarized 13C MRSI with in vivo applications to transgenic mouse models of cancer. Magn Reson Med. 2009; 63(2):312-321. PMCID: PMC2829256
  • Ward CS, Venkatesh HS, Chaumeil MM, Brandes AH, Van Criekinge M, Dafni H, Sukumar S, Nelson SJ, Vigneron DB, Kurhanewicz J, James CD, Haas-Kogan DA, Ronen SM. Noninvasive Detection of Target Modulation following Phosphatidylinositol 3-Kinase Inhibition Using Hyperpolarized 13C Magnetic Resonance Spectroscopy. Cancer Res. 2010; 70(4):1296-305. PMCID: PMC2822895
  • Lupo JM, Chen AP, Zierhut ML, Bok RA, Cunningham CC, Kurhanewicz J, Vigneron DB, Nelson SJ. Analysis of hyperpolarized dynamic 13C lactate imaging in a transgenic mouse model of prostate cancer. Magn Reson Imaging. 2010; 28(2):153-62. PMCID: PMC3075841
  • Larson PE, Bok R, Kerr AB, Lustig M, Hu S, Chen AP, Nelson SJ, Pauly JM, Kurhanewicz J, Vigneron DB. Investigation of tumor hyperpolarized [113C]-pyruvate dynamics using time-resolved multiband RF excitation echo-planar MRSI. Magn Reson Med. 2010; 63(3):582-91. PMCID: PMC2844437
  • Hu S, Balakrishnan A, Bok RA, Anderton B, Larson PEZ, Nelson SJ, Kurhanewicz J, Vigneron DB, Goga A. 13C-Pyruvate Imaging Reveals Alterations in Glycolyisis that Precede c-Myc-Induced Tumor Formation and Regression. Cell Metabolism. 2011; 14(1):131-142. NIHMS306072
  • Kurhanewicz J, Vigneron DB, Brindle K, Chekmenev E, Comment A, Cunningham C, DeBerardinis R, Green G, Leach M, Rajan S, Rizi R, Ross B, Warren W, Malloy C. Analysis of Cancer Metabolism by Imaging Hyperpolarized Nuclei: Prospects for Translation to Clinical Research. Neoplasia. 2011; 13(2):81-97. PMCID: PMC3033588