University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Maria Wei, MD, PhD

Maria Wei, MD, PhD

Associate Professor of Dermatology, Director of Dermatology Genetics Clinic, UCSF

Cancer Center Program Memberships

Experimental Therapeutics | Cancer Genetics

Education

University of Michigan, Ann Arbor, MI B.S., High Honors, 1983, Chemistry, Computer Science
Duke University, Durham, NC Ph.D. 1991 Immunology
Duke University, Durham, NC M.D. 1992 Medicine
Brigham and Women’s Hospital, Boston, MA Intern 1993 Internal Medicine
University of California, San Francisco Resident 1996 Dermatology
University of California, San Francisco Fellow 1997 Biochemistry/Biophysics


Professional Experience

  • 1997-2003
    Clinical Instructor, Department of Dermatology, University of California, San Francisco
  • 1997-present
    Staff Physician, Dermatology Service, San Francisco Veterans Affairs Medical Center
  • 2003-2010
    Assistant Professor, of Dermatology, University of California, San Francisco
  • 2009-present
    Director, Pigmented Lesion Clinic/Melanoma Surveillance Clinic, UCSF
  • 2010-present
    Associate Professor, Department of Dermatology, University of California, San Francisco
  • 2015-present
    Director, Dermatology Genetics Clinic, UCSF

Honors & Awards

  • 1998
    Mentorship Award, Women’s Dermatologic Society
  • 1999
    Research Career Development Award, Department of Veterans Affairs
  • 2005
    Young Investigator Award, NCIRE/SFVAMC
  • 2013
    Estella Medrano Award, PanAmerican Society for Pigment Cell Research
  • 2014
    Bay Area’s Top Docs, Melanoma and Pigment Disorders, San Francisco Magazine
  • 2015
    Bay Area’s Top Docs, Melanoma and Pigment Disorders, San Francisco Magazine

Selected Publications

  1. Nosrati A, Berliner JG, Goel S, McGuire J, Morhenn V, de Souza JR, Yeniay Y, Singh R, Lee K, Nakamura M, Wu RR, Griffin A, Grimes B, Linos E, Chren MM, Grekin R, Wei ML. Outcomes of Melanoma In Situ Treated With Mohs Micrographic Surgery Compared With Wide Local Excision. JAMA Dermatol. 2017 May 01; 153(5):436-441.
    View on PubMed
  2. Singh RK, Lee KM, Vujkovic-Cvijin I, Ucmak D, Farahnik B, Abrouk M, Nakamura M, Zhu TH, Bhutani T, Wei M, Liao W. The role of IL-17 in vitiligo: A review. Autoimmun Rev. 2016 Apr; 15(4):397-404.
    View on PubMed
  3. Choudhry A, Hong J, Chong K, Jiang B, Hartman R, Chu E, Nelson K, Wei ML, Nguyen T. Patients' preferences for biopsy result notification in an era of electronic messaging methods. JAMA Dermatol. 2015 May; 151(5):513-21.
    View on PubMed
  4. Yue L, Huang ZM, Fong S, Leong S, Jakowatz JG, Charruyer-Reinwald A, Wei M, Ghadially R. Targeting ALDH1 to decrease tumorigenicity, growth and metastasis of human melanoma. Melanoma Res. 2015 Apr; 25(2):138-48.
    View on PubMed
  5. Nosrati A, Wei ML. Sex disparities in melanoma outcomes: the role of biology. Arch Biochem Biophys. 2014 Dec 1; 563:42-50.
    View on PubMed
  6. Man MQ, Lin TK, Santiago JL, Celli A, Zhong L, Huang ZM, Roelandt T, Hupe M, Sundberg JP, Silva KA, Crumrine D, Martin-Ezquerra G, Trullas C, Sun R, Wakefield JS, Wei ML, Feingold KR, Mauro TM, Elias PM. Basis for enhanced barrier function of pigmented skin. J Invest Dermatol. 2014 Sep; 134(9):2399-407.
    View on PubMed
  7. Huang ZM, Chinen M, Chang PJ, Xie T, Zhong L, Demetriou S, Patel MP, Scherzer R, Sviderskaya EV, Bennett DC, Millhauser GL, Oh DH, Cleaver JE, Wei ML. Targeting protein-trafficking pathways alters melanoma treatment sensitivity. Proc Natl Acad Sci U S A. 2012 Jan 10; 109(2):553-8.
    View on PubMed
  8. Agarwal P, Verzi MP, Nguyen T, Hu J, Ehlers ML, McCulley DJ, Xu SM, Dodou E, Anderson JP, Wei ML, Black BL. The MADS box transcription factor MEF2C regulates melanocyte development and is a direct transcriptional target and partner of SOX10. Development. 2011 Jun; 138(12):2555-65.
    View on PubMed
  9. Xie T, Nguyen T, Hupe M, Wei ML. Multidrug resistance decreases with mutations of melanosomal regulatory genes. Cancer Res. 2009 Feb 1; 69(3):992-9.
    View on PubMed
  10. Nguyen T, Wei ML. Hermansky-Pudlak HPS1/pale ear gene regulates epidermal and dermal melanocyte development. J Invest Dermatol. 2007 Feb; 127(2):421-8.
    View on PubMed
  11. Wei ML. Hermansky-Pudlak syndrome: a disease of protein trafficking and organelle function. Pigment Cell Res. 2006 Feb; 19(1):19-42.
    View on PubMed
  12. Nguyen T, Wei ML. Characterization of melanosomes in murine Hermansky-Pudlak syndrome: mechanisms of hypopigmentation. J Invest Dermatol. 2004 Feb; 122(2):452-60.
    View on PubMed
  13. Nguyen T, Novak EK, Kermani M, Fluhr J, Peters LL, Swank RT, Wei ML. Melanosome morphologies in murine models of hermansky-pudlak syndrome reflect blocks in organelle development. J Invest Dermatol. 2002 Nov; 119(5):1156-64.
    View on PubMed
  14. Wei ML, Bonzelius F, Scully RM, Kelly RB, Herman GA. GLUT4 and transferrin receptor are differentially sorted along the endocytic pathway in CHO cells. J Cell Biol. 1998 Feb 9; 140(3):565-75.
    View on PubMed

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