University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Kwun Wah Wen, MD, PhD

Kwun Wah Wen, MD, PhD

Assistant Professor of Clinical Pathology, UCSF

Cancer Center Program Memberships

Hematopoietic Malignancies

Education

  • University of Washington, Seattle, BS, 06/2004, (Magna Cum Laude) Biochemistry
  • University of North Carolina at Chapel Hill, MD, 05/2012, Medicine
  • University of North Carolina at Chapel Hill, PhD, 06/2010, Microbiology and Immunology
  • Hospital of the University of Pennsylvania, Resident, 07/2013, Internal Medicine
  • University of Pennsylvania, Postdoctoral Associate, 05/2014, Hematology
  • University of California, San Francisco, Resident, 06/2016, Pathology
  • University of California, San Francisco, Fellow, 06/2017, Hematopathology
  • University of California, San Francisco, Fellow/Chief Resident, 06/2018, Gastrointestinal/ Liver Pathology

Honors & Awards

  • 2001
    Mary Gates Scholarship
  • 2002
    Ronald E. McNair Presidential Scholarship
  • 2003
    Herschel and Caryl Roman Undergraduate Science Scholarship
  • 2004
    American Institute of Chemists Foundation Student Award
  • 2004
    Phi Beta Kappa
  • 2004
    Distinction in Biochemistry
  • 2004
    Medical Scientist Training Program
  • 2006
    Harold C. Pillsbury, M.D. Student Research Award
  • 2009
    Lineberger Annual Scientific Competition Winner
  • 2010
    University Cancer Research Fund Scholarship
  • 2010
    Annual G. Philip Manire Graduate Student Excellence in Research Award
  • 2010
    Lineberger Comprehensive Cancer Center Graduate Fellow Award in Basic Sciences
  • 2017
    Best Abstract Award, International Association of Chinese Pathologists
  • 2017
    Arthur Purdy Stout Stipend Award
  • 2018
    Best Abstract Award (2nd place in platform), Chinese American Pathologists Association
  • 2018
    Best Abstract Award (runner up), Rodger C. Haggitt Gastrointestinal Pathology Society
  • 2019
    F. Stephen Vogel Award, United States and Canadian Academy of Pathology

Selected Publications

  1. Chang WC, M Yeh B, Chu L, Kim SY, Wen KW, Chiu SH, Ding CC, Wu EH, Roberts JP, Huang GS, Hsu HH. Post-operative assessment in patients after liver transplantation: imaging parameters associated with 1-year graft failure. Eur Radiol. 2020 Aug 30.
    View on PubMed
  2. Freise J, Mena J, Wen KW, Stoller M, Ho S, Corvera C. A rare presentation of hepatolithiasis in an adolescent patient: A case report. Int J Surg Case Rep. 2020; 72:343-345.
    View on PubMed
  3. Wen KW, Fakhri B, Menke J, Ruiz-Cordero R, Gill RM, Ohgami RS. Complexities in the diagnosis of large B-cell lymphomas, classic Hodgkin lymphomas and overlapping peripheral T-cell lymphomas simplified: An evidence-based guide. Ann Diagn Pathol. 2020 Jun; 46:151534.
    View on PubMed
  4. Yamamoto K, Venida A, Yano J, Biancur DE, Kakiuchi M, Gupta S, Sohn ASW, Mukhopadhyay S, Lin EY, Parker SJ, Banh RS, Paulo JA, Wen KW, Debnath J, Kim GE, Mancias JD, Fearon DT, Perera RM, Kimmelman AC. Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I. Nature. 2020 05; 581(7806):100-105.
    View on PubMed
  5. Wen KW, Rabinovitch PS, Wang D, Mattis AN, Ferrell LD, Choi WT. Utility of DNA flow cytometry in distinguishing between malignant and benign intrahepatic biliary lesions. Virchows Arch. 2020 Oct; 477(4):527-534.
    View on PubMed
  6. Wen KW, Umetsu SE, Goldblum JR, Gill RM, Kim GE, Joseph NM, Rabinovitch PS, Kakar S, Lauwers GY, Choi WT. DNA flow cytometric and interobserver study of crypt cell atypia in inflammatory bowel disease. Histopathology. 2019 Oct; 75(4):578-588.
    View on PubMed
  7. Raghavan K, Wen KW, Small EJ, Ha P, Flavell RR. Incidentally Detected Oropharyngeal Squamous Cell Carcinoma on 18F-Fluciclovine PET/CT. Clin Nucl Med. 2019 May; 44(5):e367-e369.
    View on PubMed
  8. Wen KW, Kim GE, Rabinovitch PS, Wang D, Mattis AN, Choi WT. Diagnosis, risk stratification, and management of ampullary dysplasia by DNA flow cytometric analysis of paraffin-embedded tissue. Mod Pathol. 2019 09; 32(9):1291-1302.
    View on PubMed
  9. Mukhtar RA, Holland M, Sieber DA, Wen KW, Rugo HS, Kadin ME, Bean GR. Synchronous Breast Implant-associated Anaplastic Large Cell Lymphoma and Invasive Carcinoma: Genomic Profiling and Management Implications. Plast Reconstr Surg Glob Open. 2019 Apr; 7(4):e2188.
    View on PubMed
  10. Wen KW, Gill RM. Immature Terminal Deoxynucleotidyl Transferase Positive B Cells are Detected in a Subset of Adult and Pediatric Liver Biopsies. Appl Immunohistochem Mol Morphol. 2019 04; 27(4):319-324.
    View on PubMed
  11. Wen KW, Rabinovitch PS, Wang D, Huang D, Mattis AN, Choi WT. Utility of DNA Flow Cytometric Analysis of Paraffin-embedded Tissue in the Risk Stratification and Management of 'Indefinite for dysplasia' in Patients With Inflammatory Bowel Disease. J Crohns Colitis. 2019 Mar 30; 13(4):472-481.
    View on PubMed
  12. Lewin SM, Wen KW, Velayos FS, Mahadevan U, Beck KR. How Dye May Prevent Dying from Cancer: Perceiving Imperceptible Dysplasia in Inflammatory Bowel Disease. Dig Dis Sci. 2019 01; 64(1):52-55.
    View on PubMed
  13. Abrahams CL, Li X, Embry M, Yu A, Krimm S, Krueger S, Greenland NY, Wen KW, Jones C, DeAlmeida V, Solis WA, Matheny S, Kline T, Yam AY, Stafford R, Wiita AP, Hallam T, Lupher M, Molina A. Targeting CD74 in multiple myeloma with the novel, site-specific antibody-drug conjugate STRO-001. Oncotarget. 2018 Dec 28; 9(102):37700-37714.
    View on PubMed
  14. Choi WT, Wen KW, Rabinovitch PS, Huang D, Mattis AN, Gill RM. DNA content analysis of colorectal serrated lesions detects an aneuploid subset of inflammatory bowel disease-associated serrated epithelial change and traditional serrated adenomas. Histopathology. 2018 Sep; 73(3):464-472.
    View on PubMed
  15. Wen KW, Rabinovitch PS, Huang D, Mattis AN, Lauwers GY, Choi WT. Use of DNA flow cytometry in the diagnosis, risk stratification, and management of gastric epithelial dysplasia. Mod Pathol. 2018 10; 31(10):1578-1587.
    View on PubMed
  16. Wen KW, Grenert JP, Joseph NM, Shafizadeh N, Huang A, Hosseini M, Kakar S. Genomic profile of appendiceal goblet cell carcinoid is distinct compared to appendiceal neuroendocrine tumor and conventional adenocarcinoma. Hum Pathol. 2018 07; 77:166-174.
    View on PubMed
  17. Bhavanasi D, Wen KW, Liu X, Vergez F, Danet-Desnoyers G, Carroll M, Huang J, Klein PS. Signaling mechanisms that regulate ex vivo survival of human acute myeloid leukemia initiating cells. Blood Cancer J. 2017 11 30; 7(12):636.
    View on PubMed
  18. Bean GR, Wen KW, Horvai AE. Adipocyte size variability in benign and malignant lipomatous tumors and morphologic mimics: a quantitative definition using digital pathology. Hum Pathol. 2018 02; 72:52-58.
    View on PubMed
  19. Wen KW, Hale G, Shafizadeh N, Hosseini M, Huang A, Kakar S. Appendiceal goblet cell carcinoid: common errors in staging and clinical interpretation with a proposal for an improved terminology. Hum Pathol. 2017 07; 65:187-193.
    View on PubMed
  20. Chen W, Sin SH, Wen KW, Damania B, Dittmer DP. Hsp90 inhibitors are efficacious against Kaposi Sarcoma by enhancing the degradation of the essential viral gene LANA, of the viral co-receptor EphA2 as well as other client proteins. PLoS Pathog. 2012; 8(11):e1003048.
    View on PubMed

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