University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Iwei Yeh , MD, PhD

Iwei Yeh , MD, PhD

Assistant Professor, Dermatology and Pathology, UCSF

Cancer Center Program Memberships

Cancer Immunology | Cancer Genetics

Education

Harvard College, AB, 06/97, Summa Cum Laude, Biochemical Sciences
Stanford University, MD, 06/06
Stanford University, PhD, 06/06, Biomedical Informatics
Santa Clara Valley Medical Center, Intern, 06/07, Transitional Internship
University of Washington, Resident, 06/10, Dermatology
University of California, San Francisco, Fellow, 06/11, Dermatopathology


Professional Experience

  • 2011-2011
    Assistant Member, Pathology, Memorial Sloan Kettering Cancer Center
  • 2011-present
    Assistant Professor, Dermatology and Pathology, University of California, San Francisco

Honors & Awards

  • 1993
    National Merit Scholar
  • 1994
    Valedictorian, California High School; San Ramon, CA
  • 1996
    Goldwater Scholarship for Scientific Excellence
  • 1997
    Phi Beta Kappa, Harvard College Chapter, Cambridge, MA
  • 1998
    Medical Scientist Training Program, Predoctoral Fellowship, National Institutes of Health
  • 2003
    Graduate Fellowship, National Library of Medicine
  • 2006
    Doctoral Commencement Speaker, Stanford Medical School

Selected Publications

  1. Goode B, Joseph NM, Stevers M, Van Ziffle J, Onodera C, Talevich E, Grenert JP, Yeh I, Bastian BC, Phillips JJ, Garg K, Rabban JT, Zaloudek C, Solomon DA. Adenomatoid tumors of the male and female genital tract are defined by TRAF7 mutations that drive aberrant NF-kB pathway activation. Mod Pathol. 2017 Nov 17.
    View on PubMed
  2. Yeh I, Lang UE, Durieux E, Tee MK, Jorapur A, Shain AH, Haddad V, Pissaloux D, Chen X, Cerroni L, Judson RL, LeBoit PE, McCalmont TH, Bastian BC, de la Fouchardière A. Combined activation of MAP kinase pathway and ß-catenin signaling cause deep penetrating nevi. Nat Commun. 2017 Sep 21; 8(1):644.
    View on PubMed
  3. Lang UE, Yeh I, McCalmont TH. Molecular Melanoma Diagnosis Update: Gene Fusion, Genomic Hybridization, and Massively Parallel Short-Read Sequencing. Clin Lab Med. 2017 Sep; 37(3):473-484.
    View on PubMed
  4. Matsumoto A, Yeh I, Schwartz B, Rosenblum M, Schmidt TH. Chronic Helicobacter cinaedi cellulitis diagnosed by microbial polymerase chain reaction. JAAD Case Rep. 2017 Sep; 3(5):398-400.
    View on PubMed
  5. Foley N, Van Ziffle J, Yu J, Qi Z, Grenert JP, Yeh I, Bastian B, Kogan S, Mannis GN. Acute myeloid leukemia with t(14;21) involving RUNX1 and SYNE2: A novel favorable-risk translocation? Cancer Genet. 2017 Oct; 216-217:74-78.
    View on PubMed
  6. Asgari MM, Shen L, Sokil MM, Yeh I, Jorgenson E. Prognostic factors and survival in acral lentiginous melanoma. Br J Dermatol. 2017 Aug; 177(2):428-435.
    View on PubMed
  7. Krings G, Joseph NM, Bean GR, Solomon D, Onodera C, Talevich E, Yeh I, Grenert JP, Hosfield E, Crawford ED, Jordan RC, van Zante A, Zaloudek C, Shin SJ, Chen YY. Genomic profiling of breast secretory carcinomas reveals distinct genetics from other breast cancers and similarity to mammary analog secretory carcinomas. Mod Pathol. 2017 Aug; 30(8):1086-1099.
    View on PubMed
  8. Kline CN, Joseph NM, Grenert JP, van Ziffle J, Talevich E, Onodera C, Aboian M, Cha S, Raleigh DR, Braunstein S, Torkildson J, Samuel D, Bloomer M, Campomanes AGA, Banerjee A, Butowski N, Raffel C, Tihan T, Bollen AW, Phillips JJ, Korn WM, Yeh I, Bastian BC, Gupta N, Mueller S, Perry A, Nicolaides T, Solomon DA. Targeted next-generation sequencing of pediatric neuro-oncology patients improves diagnosis, identifies pathogenic germline mutations, and directs targeted therapy. Neuro Oncol. 2017 05 01; 19(5):699-709.
    View on PubMed
  9. Theiler M, Oza VS, Mathes EF, Dvorak CC, McCalmont TH, Yeh I, Sidbury R, Cordoro KM. Eosinophilic Pustular Folliculitis in Children after Stem Cell Transplantation: An Eruption Distinct from Graft-Versus-Host Disease. Pediatr Dermatol. 2017 May; 34(3):326-330.
    View on PubMed
  10. Dong Q, Gao H, Shi Y, Zhang F, Gu X, Wu A, Wang D, Chen Y, Bandyopadhyay A, Yeh IT, Daniel BJ, Chen Y, Zou Y, Rebel VL, Walter CA, Lu J, Huang C, Sun LZ. Aging is associated with an expansion of CD49fhi mammary stem cells that show a decline in function and increased transformation potential. Aging (Albany NY). 2016 Nov 15; 8(11):2754-2776.
    View on PubMed
  11. Joseph NM, Chen YY, Nasr A, Yeh I, Talevich E, Onodera C, Bastian BC, Rabban JT, Garg K, Zaloudek C, Solomon DA. Genomic profiling of malignant peritoneal mesothelioma reveals recurrent alterations in epigenetic regulatory genes BAP1, SETD2, and DDX3X. Mod Pathol. 2017 Feb; 30(2):246-254.
    View on PubMed
  12. Yeh I, Tee MK, Botton T, Shain AH, Sparatta AJ, Gagnon A, Vemula SS, Garrido MC, Nakamaru K, Isoyama T, McCalmont TH, LeBoit PE, Bastian BC. NTRK3 kinase fusions in Spitz tumours. J Pathol. 2016 Nov; 240(3):282-290.
    View on PubMed
  13. Yeh I. Recent advances in molecular genetics of melanoma progression: implications for diagnosis and treatment. F1000Res. 2016; 5.
    View on PubMed
  14. Liu SY, Joseph NM, Ravindranathan A, Stohr BA, Greenland NY, Vohra P, Hosfield E, Yeh I, Talevich E, Onodera C, Van Ziffle JA, Grenert JP, Bastian BC, Chen YY, Krings G. Genomic profiling of malignant phyllodes tumors reveals aberrations in FGFR1 and PI-3 kinase/RAS signaling pathways and provides insights into intratumoral heterogeneity. Mod Pathol. 2016 Sep; 29(9):1012-27.
    View on PubMed
  15. Kline CN, Joseph NM, Grenert JP, van Ziffle J, Yeh I, Bastian BC, Mueller S, Solomon DA. Inactivating MUTYH germline mutations in pediatric patients with high-grade midline gliomas. Neuro Oncol. 2016 May; 18(5):752-3.
    View on PubMed
  16. Yeh LC, Banerjee A, Prasad V, Tuszynski JA, Weis AL, Bakos T, Yeh IT, Ludueña RF, Lee JC. Effect of CH-35, a novel anti-tumor colchicine analogue, on breast cancer cells overexpressing the ßIII isotype of tubulin. Invest New Drugs. 2016 Feb; 34(1):129-37.
    View on PubMed
  17. Shain AH, Yeh I, Kovalyshyn I, Sriharan A, Talevich E, Gagnon A, Dummer R, North J, Pincus L, Ruben B, Rickaby W, D'Arrigo C, Robson A, Bastian BC. The Genetic Evolution of Melanoma from Precursor Lesions. N Engl J Med. 2015 Nov 12; 373(20):1926-36.
    View on PubMed
  18. Shain AH, Garrido M, Botton T, Talevich E, Yeh I, Sanborn JZ, Chung J, Wang NJ, Kakavand H, Mann GJ, Thompson JF, Wiesner T, Roy R, Olshen AB, Gagnon A, Gray JW, Huh N, Hur JS, Busam KJ, Scolyer RA, Cho RJ, Murali R, Bastian BC. Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway. Nat Genet. 2015 Oct; 47(10):1194-9.
    View on PubMed
  19. Menzies AM, Yeh I, Botton T, Bastian BC, Scolyer RA, Long GV. Clinical activity of the MEK inhibitor trametinib in metastatic melanoma containing BRAF kinase fusion. Pigment Cell Melanoma Res. 2015 Sep; 28(5):607-10.
    View on PubMed
  20. Yeh I, Botton T, Talevich E, Shain AH, Sparatta AJ, de la Fouchardiere A, Mully TW, North JP, Garrido MC, Gagnon A, Vemula SS, McCalmont TH, LeBoit PE, Bastian BC. Activating MET kinase rearrangements in melanoma and Spitz tumours. Nat Commun. 2015 May 27; 6:7174.
    View on PubMed

Go to UCSF Profiles, powered by CTSI