Associate Professor, Department of Radiation Oncology, UCSF
Research Summary
My primary clinical and research interests include head and neck, thoracic, and cutaneous malignancies, where I have developed and led multiple clinical trials, both within UCSF and across sites nationwide and overseas. I am interested in the development and evaluation of new therapeutic techniques, which to me include novel molecular targeted agents and immunotherapies as well as state-of-the-art technical advances in radiation therapy. I have special interests in virally driven malignancies associated with humanpapillomavirus (HPV), Epstein-Barr virus (EBV), and Merkel cell polyomavirus. My research has entailed collaborating with laboratory-based investigators to identify patient, tumor, and technical characteristics that influence prognosis and response to specific therapies, including tissue-, blood-, and imaging-based biomarkers. Other university responsibilities include co-leading the site committees for clinical trial development in cutaneous and head and neck cancers at the UCSF HDFCCC and serving on the Cancer Committee which maintains our accreditation through the American College of Surgeons. Nationally, I have served as the chair of the scientific program and nominating committees for the American Radium Society (ARS), chair of the Appropriateness Committee guidelines for radiation oncology at the American College of Radiology (ACR), and head and neck senior editor at the International Journal for Radiation Oncology Biology Physics (IJROBP). I have been on the scientific program committees of the American Society for Radiation Oncology (ASTRO), the International Association for the Study of Lung Cancer (IASLC), and the American Head and Neck Society (AHNS). I am a member of the NRG Oncology Head and Neck Steering Committee, NCI’s Head and Neck Recurrent/Metastatic Disease Task Force, and the NCCN Head and Neck Cancers guidelines committee. I am a national boards examiner for the American Board of Radiology.
Education
2002, University of Pennsylvania, Philadelphia, PA, M.D., Ph.D., Medicine/English
2003, U. T. – M. D. Anderson Cancer Center, Internship, Medicine/Surgery
2007, U. T. – M. D. Anderson Cancer Center, Residency, Radiation Oncology
Professional Experience
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2007-2013
Assistant Professor of Clinical Radiation Oncology, University of California, San Francisco
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2007-present
Consultant in Radiology, San Francisco Veterans Administration Medical Center
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2008-2013
Assistant Professor in Otolaryngology-Head and Neck Surgery, by courtesy
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2013-present
Associate Professor of Clinical Radiation Oncology, University of California, San Francisco
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2013-present
Associate Professor in Otolaryngology-Head and Neck Surgery, by courtesy
Honors & Awards
- 1992
Mellon Fellow in the Humanities, Andrew W. Mellon Foundation - 1995
Benjamin Franklin Medical Scholar Fellowship, University of Pennsylvania - 2004
Thomas Barkley Award, M. D. Anderson Cancer Center - 2005
Fellowship, Korean American Society for Therapeutic Radiology & Oncology - 2006
Jesse H. Jones Fellowship in Cancer Education, M. D. Anderson Cancer Center - 2006
Outstanding Resident Presentation Award, Texas Radiological Society - 2006
A. Lavoy Moore Endowment Fund, M. D. Anderson Cancer Center - 2006
Eleanor Montague Distinguished Resident Award, American Association of Women Radiologists - 2008
Joan F. Giambalvo Memorial Scholarship, AMA Women Physicians Congress - 2009
Best Doctors in America, 2009-2014 - 2011
Educator of the Year Award, Association of Residents in Radiation Oncology
Selected Publications
- Paulsson AK, Yom SS, Anwar M, Pinnaduwage D, Sudhyadhom A, Gottschalk AR, Chang AJ, Descovich M. Respiration-Induced Intraorgan Deformation of the Liver. Technol Cancer Res Treat. 2017 Jan 01; 1533034616687193.
View on PubMed - Siddiqui F, Smith RV, Yom SS, Beitler JJ, Busse PM, Cooper JS, Hanna EY, Jones CU, Koyfman SA, Quon H, Ridge JA, Saba NF, Worden F, Yao M, Salama JK. ACR appropriateness criteria® nasal cavity and paranasal sinus cancers. Head Neck. 2016 Dec 29.
View on PubMed - Yom SS. Is Induction Chemotherapy Needed to Select Patients for Deintensified Treatment of Human Papillomavirus-Associated Oropharyngeal Cancer? J Clin Oncol. 2016 Dec 28; JCO2016710681.
View on PubMed - Pugh SL, Wyatt G, Wong RK, Sagar SM, Yueh B, Singh AK, Yao M, Nguyen-Tan PF, Yom SS, Cardinale FS, Sultanem K, Hodson DI, Krempl GA, Chavez A, Yeh AM, Bruner DW. Exploratory Factor Analysis of NRG Oncology's University of Washington Quality of Life Questionnaire-RTOG Modification. J Pain Symptom Manage. 2017 Jan; 53(1):139-145.e2.
View on PubMed - Chan JW, Parvathaneni U, Yom SS. Reducing radiation-related morbidity in the treatment of nasopharyngeal carcinoma. Future Oncol. 2016 Nov 23.
View on PubMed - Karam I, Yao M, Heron DE, Poon I, Koyfman SA, Yom SS, Siddiqui F, Lartigau E, Cengiz M, Yamazaki H, Hara W, Phan J, Vargo JA, Lee V, Foote RL, Harter KW, Lee NY, Sahgal A, Lo SS. Survey of current practices from the International Stereotactic Body Radiotherapy Consortium (ISBRTC) for head and neck cancers. Future Oncol. 2016 Nov 15.
View on PubMed - Braunstein S, Glastonbury CM, Chen J, Quivey JM, Yom SS. Impact of Neuroradiology-Based Peer Review on Head and Neck Radiotherapy Target Delineation. AJNR Am J Neuroradiol. 2017 Jan; 38(1):146-153.
View on PubMed - Zevallos JP, Yom SS. Redefining the Role of Surgical Management in the Evolving Landscape of Oropharyngeal Cancer. J Oncol Pract. 2016 Nov; 12(11):1185-1187.
View on PubMed - Yu Y, Mabray M, Silveira W, Shen PY, Ryan WR, Uzelac A, Yom SS. Earlier and more specific detection of persistent neck disease with diffusion-weighted MRI versus subsequent PET/CT after definitive chemoradiation for oropharyngeal squamous cell carcinoma. Head Neck. 2016 Oct 11.
View on PubMed - Beitler JJ, Quon H, Jones CU, Salama JK, Busse PM, Cooper JS, Koyfman SA, Ridge JA, Saba NF, Siddiqui F, Smith RV, Worden F, Yao M, Yom SS. ACR Appropriateness Criteria(®) Locoregional therapy for resectable oropharyngeal squamous cell carcinomas. Head Neck. 2016 Sep; 38(9):1299-309.
View on PubMed - Tan DS, Yom SS, Tsao MS, Pass HI, Kelly K, Peled N, Yung RC, Wistuba II, Yatabe Y, Unger M, Mack PC, Wynes MW, Mitsudomi T, Weder W, Yankelevitz D, Herbst RS, Gandara DR, Carbone DP, Bunn PA, Mok TS, Hirsch FR. The International Association for the Study of Lung Cancer Consensus Statement on Optimizing Management of EGFR Mutation-Positive Non-Small Cell Lung Cancer: Status in 2016. J Thorac Oncol. 2016 Jul; 11(7):946-63.
View on PubMed - Saba NF, Salama JK, Beitler JJ, Busse PM, Cooper JS, Jones CU, Koyfman S, Quon H, Ridge JA, Siddiqui F, Worden F, Yao M, Yom SS. ACR Appropriateness criteria® for nasopharyngeal carcinoma. Head Neck. 2016 Jul; 38(7):979-86.
View on PubMed - Shugard E, Chen J, Quivey JM, Glastonbury CM, Khanafshar E, Garsa AA, George JR, Yom SS. Does radiation dose matter in thyroid cancer?: Patterns of local-regional failure in recurrent and metastatic well-differentiated thyroid cancers treated with dose-painted intensity-modulated radiation therapy. J Med Imaging Radiat Oncol. 2016 Aug; 60(4):560-7.
View on PubMed - Singer L, Calkins SM, E Horvai A, R Ryan W, Yom SS. Xanthogranuloma in the heavily irradiated low neck in a patient with head and neck cancer. J Otolaryngol Head Neck Surg. 2016; 45(1):20.
View on PubMed - Anwar M, Yu Y, Glastonbury CM, El-Sayed IH, Yom SS. Delineation of radiation therapy target volumes for cutaneous malignancies involving the ophthalmic nerve (cranial nerve V-1) pathway. Pract Radiat Oncol. 2016 Nov - Dec; 6(6):e277-e281.
View on PubMed - Wyatt G, Pugh SL, Wong RK, Sagar S, Singh AK, Koyfman SA, Nguyen-Tân PF, Yom SS, Cardinale FS, Sultanem K, Hodson I, Krempl GA, Lukaszczyk B, Yeh AM, Berk L. Xerostomia health-related quality of life: NRG oncology RTOG 0537. Qual Life Res. 2016 Sep; 25(9):2323-33.
View on PubMed - Chapman CH, Saba NF, Yom SS. Targeting epidermal growth factor receptor for head and neck squamous cell carcinoma: still lost in translation? Ann Transl Med. 2016 Feb; 4(4):80.
View on PubMed - Corry J, Yom SS. The Multidisciplinary Approach Needs to Extend Into Head and Neck Cancer Clinical Trials. Int J Radiat Oncol Biol Phys. 2016 Feb 1; 94(2):217-20.
View on PubMed - Koyfman SA, Cooper JS, Beitler JJ, Busse PM, Jones CU, McDonald MW, Quon H, Ridge JA, Saba NF, Salama JK, Siddiqui F, Smith RV, Worden F, Yao M, Yom SS. ACR Appropriateness Criteria(®) Aggressive Nonmelanomatous Skin Cancer of the Head and Neck. Head Neck. 2016 Feb; 38(2):175-82.
View on PubMed - Yom SS. The softer (and furrier) side of oncology. Pract Radiat Oncol. 2016 Sep-Oct; 6(5):285-6.
View on PubMed
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