University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Sue S. Yom, MD, PhD

Sue S. Yom, MD, PhD

Professor, Department of Radiation Oncology, UCSF

Cancer Center Program Memberships

Experimental Therapeutics

Research Summary

My primary clinical and research interests include head and neck, thoracic, and cutaneous malignancies, where I have developed and led multiple clinical trials, both within UCSF and across sites nationwide and overseas. I am interested in the development and evaluation of new therapeutic techniques, which to me include novel molecular targeted agents and immunotherapies as well as state-of-the-art technical advances in radiation therapy. I have special interests in virally driven malignancies associated with humanpapillomavirus (HPV), Epstein-Barr virus (EBV), and Merkel cell polyomavirus. My research has entailed collaborating with laboratory-based investigators to identify patient, tumor, and technical characteristics that influence prognosis and response to specific therapies, including tissue-, blood-, and imaging-based biomarkers. Other university responsibilities include co-leading the site committees for clinical trial development in cutaneous and head and neck cancers at the UCSF HDFCCC and serving on the Cancer Committee which maintains our accreditation through the American College of Surgeons. Nationally, I have served as the chair of the scientific program and nominating committees for the American Radium Society (ARS), chair of the Appropriateness Committee guidelines for radiation oncology at the American College of Radiology (ACR), and head and neck senior editor at the International Journal for Radiation Oncology Biology Physics (IJROBP). I have been on the scientific program committees of the American Society for Radiation Oncology (ASTRO), the International Association for the Study of Lung Cancer (IASLC), and the American Head and Neck Society (AHNS). I am a member of the NRG Oncology Head and Neck Steering Committee, NCI’s Head and Neck Recurrent/Metastatic Disease Task Force, and the NCCN Head and Neck Cancers guidelines committee. I am a national boards examiner for the American Board of Radiology.

Education

2002, University of Pennsylvania, Philadelphia, PA, M.D., Ph.D., Medicine/English
2003, U. T. – M. D. Anderson Cancer Center, Internship, Medicine/Surgery
2007, U. T. – M. D. Anderson Cancer Center, Residency, Radiation Oncology


Professional Experience

  • 2007-2013
    Assistant Professor of Clinical Radiation Oncology, University of California, San Francisco
  • 2007-present
    Consultant in Radiology, San Francisco Veterans Administration Medical Center
  • 2008-2013
    Assistant Professor in Otolaryngology-Head and Neck Surgery, by courtesy
  • 2013-present
    Professor of Clinical Radiation Oncology, University of California, San Francisco
  • 2013-present
    Professor in Otolaryngology-Head and Neck Surgery, by courtesy

Honors & Awards

  • 1992
    Mellon Fellow in the Humanities, Andrew W. Mellon Foundation
  • 1995
    Benjamin Franklin Medical Scholar Fellowship, University of Pennsylvania
  • 2004
    Thomas Barkley Award, M. D. Anderson Cancer Center
  • 2005
    Fellowship, Korean American Society for Therapeutic Radiology & Oncology
  • 2006
    Jesse H. Jones Fellowship in Cancer Education, M. D. Anderson Cancer Center
  • 2006
    Outstanding Resident Presentation Award, Texas Radiological Society
  • 2006
    A. Lavoy Moore Endowment Fund, M. D. Anderson Cancer Center
  • 2006
    Eleanor Montague Distinguished Resident Award, American Association of Women Radiologists
  • 2008
    Joan F. Giambalvo Memorial Scholarship, AMA Women Physicians Congress
  • 2009
    Best Doctors in America, 2009-2014
  • 2011
    Educator of the Year Award, Association of Residents in Radiation Oncology

Selected Publications

  1. Chan JW, Yeh I, El-Sayed IH, Algazi AP, Glastonbury CM, Ha PK, Yom SS, van Zante A. Ultraviolet light-related DNA damage mutation signature distinguishes cutaneous from mucosal or other origin for head and neck squamous cell carcinoma of unknown primary site. Head Neck. 2019 Jan 11.
    View on PubMed
  2. Wright JL, Yom SS, Awan MJ, Dawes S, Fischer-Valuck B, Kudner R, Vega RM, Rodrigues G. Standardizing Normal Tissue Contouring for Radiation Therapy Treatment Planning: Executive summary of an ASTRO Consensus Paper. Pract Radiat Oncol. 2018 Dec 18.
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  3. Bakst RL, Glastonbury CM, Parvathaneni U, Katabi N, Hu KS, Yom SS. Perineural Invasion and Perineural Tumor Spread in Head and Neck Cancer: A Critical Review. Int J Radiat Oncol Biol Phys. 2018 Dec 15.
    View on PubMed
  4. Videtic GM, Paulus R, Singh AK, Chang JY, Parker W, Olivier KR, Timmerman RD, Komaki RR, Urbanic JJ, Stephans KL, Yom SS, Robinson CG, Belani CP, Iyengar P, Ajlouni MI, Gopaul DD, Gomez Suescun JB, McGarry RC, Choy H, Bradley JD. Long-term Follow-up on NRG Oncology RTOG 0915 (NCCTG N0927): A Randomized Phase 2 Study Comparing 2 Stereotactic Body Radiation Therapy Schedules for Medically Inoperable Patients With Stage I Peripheral Non-Small Cell Lung Cancer. Int J Radiat Oncol Biol Phys. 2018 Dec 01.
    View on PubMed
  5. Fakhry C, Nguyen-Tân PF, Lambert L, Rosenthal DI, Weber RS, Gillison ML, Trotti AM, Barrett WL, Thorstad WL, Jones CU, Yom SS, Wong SJ, Ridge JA, Rao SSD, Bonner JA, Vigneault E, Raben D, Kudrimoti MR, Harris J, Le QT. In Regard to Bossi et al. Int J Radiat Oncol Biol Phys. 2018 Nov 01; 102(3):669-670.
    View on PubMed
  6. Kearney V, Chan JW, Valdes G, Solberg TD, Yom SS. The application of artificial intelligence in the IMRT planning process for head and neck cancer. Oral Oncol. 2018 Dec; 87:111-116.
    View on PubMed
  7. Brock KK, Yom SS. Seeing What's Before Us: Imaging in the Electronic Age. Int J Radiat Oncol Biol Phys. 2018 Nov 15; 102(4):675-676.
    View on PubMed
  8. Morin O, Vallières M, Jochems A, Woodruff HC, Valdes G, Braunstein SE, Wildberger JE, Villanueva-Meyer JE, Kearney V, Yom SS, Solberg TD, Lambin P. A Deep Look Into the Future of Quantitative Imaging in Oncology: A Statement of Working Principles and Proposal for Change. Int J Radiat Oncol Biol Phys. 2018 Nov 15; 102(4):1074-1082.
    View on PubMed
  9. Le QT, Yom SS, Wee JTS, Lee AWM, Grau C, Grégoire V, Porceddu S, Welch JJ, Mehanna H. In Regard to Beadle and Anderson. Int J Radiat Oncol Biol Phys. 2018 Sep 01; 102(1):229-230.
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  10. Yom SS, Zietman AL. Red Journal Readers' Top Articles From 2017. Int J Radiat Oncol Biol Phys. 2018 Aug 01; 101(5):1011-1013.
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  11. Janopaul-Naylor J, Yom SS. In the Eye of the Maximal Storm: Surgery Versus Radiation? Int J Radiat Oncol Biol Phys. 2018 Jul 15; 101(4):759-760.
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  12. Xu MJ, Wu S, Daud AI, Yu SS, Yom SS. In-field and abscopal response after short-course radiation therapy in patients with metastatic Merkel cell carcinoma progressing on PD-1 checkpoint blockade: a case series. J Immunother Cancer. 2018 May 30; 6(1):43.
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  13. Winchester D, Lehman J, Tello T, Chimato N, Hocker T, Kim S, Chang J, Markey J, Yom SS, Ryan W, Mully T, Hodge D, Otley C, Arron ST. Undifferentiated pleomorphic sarcoma: Factors predictive of adverse outcomes. J Am Acad Dermatol. 2018 Nov; 79(5):853-859.
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  14. Colevas AD, Yom SS, Pfister DG, Spencer S, Adelstein D, Adkins D, Brizel DM, Burtness B, Busse PM, Caudell JJ, Cmelak AJ, Eisele DW, Fenton M, Foote RL, Gilbert J, Gillison ML, Haddad RI, Hicks WL, Hitchcock YJ, Jimeno A, Leizman D, Maghami E, Mell LK, Mittal BB, Pinto HA, Ridge JA, Rocco J, Rodriguez CP, Shah JP, Weber RS, Witek M, Worden F, Zhen W, Burns JL, Darlow SD. NCCN Guidelines Insights: Head and Neck Cancers, Version 1.2018. J Natl Compr Canc Netw. 2018 May; 16(5):479-490.
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  15. Chapman CH, McGuinness C, Gottschalk AR, Yom SS, Garsa AA, Anwar M, Braunstein SE, Sudhyadhom A, Keall P, Descovich M. Influence of respiratory motion management technique on radiation pneumonitis risk with robotic stereotactic body radiation therapy. J Appl Clin Med Phys. 2018 Jul; 19(4):48-57.
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  16. Xu MJ, Wu TJ, van Zante A, El-Sayed IH, Algazi AP, Ryan WR, Ha PK, Yom SS. Mortality risk after clinical management of recurrent and metastatic adenoid cystic carcinoma. J Otolaryngol Head Neck Surg. 2018 Apr 25; 47(1):28.
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  17. Yom SS, Zietman AL. Radiation Therapy in a Time of Disaster. Int J Radiat Oncol Biol Phys. 2018 Mar 15; 100(4):832-833.
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  18. Yom SS, Harari PM. When Disaster Strikes: Mitigating the Adverse Impact on Head and Neck Cancer Patients. Int J Radiat Oncol Biol Phys. 2018 Mar 15; 100(4):838-840.
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  19. Xu MJ, Lazar AA, Garsa AA, Arron ST, Ryan WR, El-Sayed IH, George JR, Algazi AP, Heaton CM, Ha PK, Yom SS. Major prognostic factors for recurrence and survival independent of the American Joint Committee on Cancer eighth edition staging system in patients with cutaneous squamous cell carcinoma treated with multimodality therapy. Head Neck. 2018 Jul; 40(7):1406-1414.
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  20. Yu Y, El-Sayed IH, McDermott MW, Theodosopoulos PV, van Zante A, Kased N, Glastonbury CM, Garsa AA, Yom SS. Dural recurrence among esthesioneuroblastoma patients presenting with intracranial extension. Laryngoscope. 2018 Oct; 128(10):2226-2233.
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