Yu Zhou, PhD

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
zhou_yu

Associate Adjunct Professor, Department of Anesthesia, UCSF

zhoue@anesthesia.ucsf.edu

Phone: (415) 206-5940
Box 1371, UCSF
San Francisco, CA 94143-1371


Education

Peking University, Beijing, China, B.S., 1988, Biochemistry
Peking University, Beijing, China, M.S., 1991, Biochemistry
Peking University, Beijing, China, Ph.D., 2000, Molecular Biology
University of California, San Francisco, CA, Postdoc, 2001-2004, Cancer Therapeutics


Professional Experience

  • 1991-1994
    Staff Scientist, Division of Biomedical Diagnostics, BBBT, Inc., Chinese Academy of Sciences, Beijing, PRC
  • 1994-2001
    Lecturer, Departments of Biochemistry and Molecular Biology, Peking University, Beijing, PRC
  • 2001-2004
    Post-doctoral Fellow, Departments of Anesthesia and Pharmaceutical Chemistry, University of California at San Francisco, San Francisco, CA 94110
  • 2004-2007
    Assistant Researcher, Departments of Anesthesia and Pharmaceutical Chemistry, University of California at San Francisco, San Francisco, CA 94110
  • 2008-2013
    Assistant Adjunct Professor, Departments of Anesthesia and Pharmaceutical Chemistry, University of California at San Francisco, San Francisco, CA 94110
  • 2013-present
    Associate Adjunct Professor, Departments of Anesthesia and Pharmaceutical Chemistry, University of California at San Francisco, San Francisco, CA 94110

Honors & Awards

  • 1984-1988
    University Scholarship, Peking University, Beijing, PRC
  • 1990
    Guang Hua Fellowship, Peking University, Beijing, PRC
  • 1996
    Taichang Fellowship, Peking University, Beijing, PRC

Selected Publications

  • Zhou Yu, Guo Yu-li, Ni Yi-sheng and Zhang Long-xiang (1993). Site-directed mutagenesis of the disulfide linkages in trypsin and its effect on enzyme activity. Chinese J. Biochem. Biophy. 26(4), 255-260
  • Zhou Yu, Zhu Sheng-geng (1998). Antithrombotic peptides and proteins in leeches. Chinese J. Hematol. 19(9), 497-498
  • Zhou Yu, Qin Hua-xia, Xu Jing-song, Huang Yi-xiu, Zhu Sheng-geng (1999). Hirudin display on the surface of bacteriaphage M13. Chinese J. Biotech. 15(1), 29-35
  • Zhou Yu, Liu Hui, Tan Tao-chao, Huang Yi-xiu, Zhu Sheng-geng (2001). Directed evolution of hirudin by DNA shuffling. Chinese J. Biochem. Mol. Biol. 17(2), 271-274
  • Goenaga AL, Zhou Y, Legay C, Bougherara H, Huang L, Liu B, Drummond DC, Kirpotin DB, Auclair C, Marks JD, Poul MA. Identification and characterization of tumor antigens by using antibody phage display and intrabody strategies. Molecular Immunology. (2007) 44(15), 3777-3788.(*equal contributions)
  • Zhou Y, Drummond DC, Zou H, Hayes ME, Adams GP, Kirpotin DB, Marks JD. Impact of single chain Fv antibody fragment affinity on nanoparticle targeting of epidermal growth factor receptor expressing tumor cells. J. Mol. Biol. (2007) 371, 934-947.
  • Yu Zhou, James D Marks. Identification of target and function specific antibodies for effective drug delivery. Methods in Molecular Biology (2009); 525: 1-16
  • Lepin EJ, Leyton JV, Zhou Y, Olafsen T, Salazar FB, McCabe KE, Hahm S, Marks JD, Reiter RE, Wu AM. An affinity matured minibody for PET imaging of prostate stem cell antigen (PSCA)-expressing tumors. Eur J Nucl Med Mol Imaging. 2010 Aug;37(8):1529-38.
  • Zhou Y, Zou H, Zhang S, Marks JD. Internalizing Cancer Antibodies from Phage Libraries Selected on Tumor Cells and Yeast-Displayed Tumor Antigens. J Mol Biol. 2010 Sep 17.