Yu Zhou, PhD

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Yu Zhou, PhD

Associate Adjunct Professor, Department of Anesthesia, UCSF

zhoue@anesthesia.ucsf.edu

Phone: (415) 206-5940
Box 1371, UCSF
San Francisco, CA 94143-1371

View on UCSF Profiles


Education

Peking University, Beijing, China, B.S., 1988, Biochemistry
Peking University, Beijing, China, M.S., 1991, Biochemistry
Peking University, Beijing, China, Ph.D., 2000, Molecular Biology
University of California, San Francisco, CA, Postdoc, 2001-2004, Cancer Therapeutics


Professional Experience

  • 1991-1994
    Staff Scientist, Division of Biomedical Diagnostics, BBBT, Inc., Chinese Academy of Sciences, Beijing, PRC
  • 1994-2001
    Lecturer, Departments of Biochemistry and Molecular Biology, Peking University, Beijing, PRC
  • 2001-2004
    Post-doctoral Fellow, Departments of Anesthesia and Pharmaceutical Chemistry, University of California at San Francisco, San Francisco, CA 94110
  • 2004-2007
    Assistant Researcher, Departments of Anesthesia and Pharmaceutical Chemistry, University of California at San Francisco, San Francisco, CA 94110
  • 2008-2013
    Assistant Adjunct Professor, Departments of Anesthesia and Pharmaceutical Chemistry, University of California at San Francisco, San Francisco, CA 94110
  • 2013-present
    Associate Adjunct Professor, Departments of Anesthesia and Pharmaceutical Chemistry, University of California at San Francisco, San Francisco, CA 94110

Honors & Awards

  • 2006
    Best in Show Poster Award, Breast Cancer Oncology Scientific Retreat, UCSF
  • 2013
    Best Therapeutics & Clinical Trials Poster Award, Breast Cancer Oncology Scientific Retreat, UCSF

Selected Publications

  1. Zhao L, Qu L, Zhou J, Sun Z, Zou H, Chen YY, Marks JD, Zhou Y. High throughput identification of monoclonal antibodies to membrane bound and secreted proteins using yeast and phage display. PLoS One. 2014; 9(10):e111339.
    View on PubMed
  2. Li K, Tavaré R, Zettlitz KA, Mumenthaler SM, Mallick P, Zhou Y, Marks JD, Wu AM. Anti-MET ImmunoPET for Non-Small Cell Lung Cancer Using Novel Fully Human Antibody Fragments. Mol Cancer Ther. 2014 Nov; 13(11):2607-17.
    View on PubMed
  3. Jones AR, Stutz CC, Zhou Y, Marks JD, Shusta EV. Identifying blood-brain-barrier selective single-chain antibody fragments. Biotechnol J. 2014 May; 9(5):664-74.
    View on PubMed
  4. Carrico ZM, Farkas ME, Zhou Y, Hsiao SC, Marks JD, Chokhawala H, Clark DS, Francis MB. N-Terminal labeling of filamentous phage to create cancer marker imaging agents. ACS Nano. 2012 Aug 28; 6(8):6675-80.
    View on PubMed
  5. Zhou Y, Zhao L, Marks JD. Selection and characterization of cell binding and internalizing phage antibodies. Arch Biochem Biophys. 2012 Oct 15; 526(2):107-13.
    View on PubMed
  6. Zhou Y, Goenaga AL, Harms BD, Zou H, Lou J, Conrad F, Adams GP, Schoeberl B, Nielsen UB, Marks JD. Impact of intrinsic affinity on functional binding and biological activity of EGFR antibodies. Mol Cancer Ther. 2012 Jul; 11(7):1467-76.
    View on PubMed
  7. Kirpotin DB, Noble CO, Hayes ME, Huang Z, Kornaga T, Zhou Y, Nielsen UB, Marks JD, Drummond DC. Building and characterizing antibody-targeted lipidic nanotherapeutics. Methods Enzymol. 2012; 502:139-66.
    View on PubMed
  8. Zhou Y, Marks JD. Discovery of internalizing antibodies to tumor antigens from phage libraries. Methods Enzymol. 2012; 502:43-66.
    View on PubMed
  9. Zhou Y, Zou H, Zhang S, Marks JD. Internalizing cancer antibodies from phage libraries selected on tumor cells and yeast-displayed tumor antigens. J Mol Biol. 2010 Nov 19; 404(1):88-99.
    View on PubMed
  10. Diaz L, Mao H, Zhou Y, Kohli M, Cassella J, Santos D, Fesseha Z, Weng K, Chen H, Bamba D, Marks JD, Goldblatt M, Kinch M. TSG101 exposure on the surface of HIV-1 infected cells: implications for monoclonal antibody therapy for HIV/AIDS. Am J Transl Res. 2010; 2(4):368-80.
    View on PubMed
  11. Lepin EJ, Leyton JV, Zhou Y, Olafsen T, Salazar FB, McCabe KE, Hahm S, Marks JD, Reiter RE, Wu AM. An affinity matured minibody for PET imaging of prostate stem cell antigen (PSCA)-expressing tumors. Eur J Nucl Med Mol Imaging. 2010 Aug; 37(8):1529-38.
    View on PubMed
  12. Zhou Y, Marks JD. Identification of target and function specific antibodies for effective drug delivery. Methods Mol Biol. 2009; 525:145-60, xv.
    View on PubMed
  13. Leung KM, Feng DX, Lou J, Zhou Y, Fung KP, Waye MM, Tsui SK, Chan PK, Marks JD, Pang SF, Kan YW. Development of human single-chain antibodies against SARS-associated coronavirus. Intervirology. 2008; 51(3):173-81.
    View on PubMed
  14. Zhou Y, Drummond DC, Zou H, Hayes ME, Adams GP, Kirpotin DB, Marks JD. Impact of single-chain Fv antibody fragment affinity on nanoparticle targeting of epidermal growth factor receptor-expressing tumor cells. J Mol Biol. 2007 Aug 24; 371(4):934-47.
    View on PubMed
  15. Goenaga AL, Zhou Y, Legay C, Bougherara H, Huang L, Liu B, Drummond DC, Kirpotin DB, Auclair C, Marks JD, Poul MA. Identification and characterization of tumor antigens by using antibody phage display and intrabody strategies. Mol Immunol. 2007 Jul; 44(15):3777-88.
    View on PubMed
  16. Horak E, Heitner T, Robinson MK, Simmons HH, Garrison J, Russeva M, Furmanova P, Lou J, Zhou Y, Yuan QA, Weiner LM, Adams GP, Marks JD. Isolation of scFvs to in vitro produced extracellular domains of EGFR family members. Cancer Biother Radiopharm. 2005 Dec; 20(6):603-13.
    View on PubMed

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