UCSF Helen Diller Family Comprehensive Cancer Center - People

JOHN S. WITTE, PHD

Professor, Epidemiology/Biostatistics and Urology, UCSF
Member, UCSF Biomedical Sciences Graduate Program (BMS)
Leader, Cancer Genetics Program, UCSF Helen Diller Family Comprehensive Cancer Center

CONTACT

wittej@humgen.ucsf.edu
(415) 502-6882 (voice)
(415) 476-1356 (fax)

Box 0794, UCSF, San Francisco, CA 94143-0794

additional websites:

Witte Lab Website

EDUCATION
University of California, Santa Barbara, CA, BS, 1986, Mathematical Sciences University of California, Berkeley, CA, MS, 1988, Industrial Engineering and Operations Research University of California, Los Angeles, CA, PhD, 1994, Epidemiology
PROFESSIONAL EXPERIENCE
1994-1995	Research Assistant Professor, Department of Preventive Medicine, University of Southern California
1995-1999	Assistant Professor, Department of Epidemiology and Biostatistics, Case Western Reserve University
1999-2003	Associate Professor, Department of Epidemiology and Biostatistics, Case Western Reserve University
2003-present	Professor, Department of Epidemiology and Biostatistics, University of California, San Francisco
2005-present	Leader, Program in Cancer Genetics and Epidemiology, UC San Francisco
2005-present	Associate Director, Institute for Human Genetics, UC, San Francisco
2008-present	Head, Division of Cancer Epidemiology, UC, San Francisco
HONORS & AWARDS
1986	Undergraduate Honors, University of California, Santa Barbara
1989-1994	National Research Service Award, NIH
1994	Ruth F. Richards Outstanding Student Award, UCLA School of Public Health Alumni Association
1999-2000	Glennan Fellow, Case Western Reserve University
2002-2003	Visiting Scientist Award, International Agency for Research on Cancer
SELECTED PUBLICATIONS
(2005-present)
*Jorgenson E, Liu X, Witte JS. Case-Control Analyses: Geneopardy! Genetic Epidemiology 2005,29:S86-91.
*Liu X, Rybicki B, Casey G, Witte JS. Relation between body size and prostate cancer in a sibling-based case-control study. Journal of Urology 2005;174:2169-2173.
*Li L, Cicek MS, Casey G, Witte JS. No Association between Genetic Polymorphisms in Insulin (INS) and Insulin Receptor Substrate-1 (IRS1) and prostate cancer. Cancer Epidemiology, Biomarkers & Prevention 2005;14:2462-2463.
*Liu X, Jorgenson E, Witte JS. Evaluation of hierarchical modeling for association studies. BioMed Central Genetics 2005;6:S104.
Tung JY, Rosen MP, Nelson LM, Turek PJ, Witte JS, Cramer DW, Reijo Pera RA. Variants in Deleted in AZoospermia-Like (DAZL) are correlated with reproductive parameters in men and women. Human Genetics 2006;118:730-740.
*Nock NL, Liu X, Cicek MS, Li L, Macarie F, Rybicki BA, Plummer SJ, MacLennan GT, Casey G, Witte JS. Polymorphisms in PAH metabolism and conjugation genes, interactions with smoking and prostate cancer risk. Cancer Epidemiology, Biomarkers & Prevention 2006;15:756-61.
Casey G, Neville PJ, Cicek MS, Plummer SJ, Krumroy LM, Curran AP, Martin MR, Liu X, Catalona WJ, Witte JS. Association between Podocalyxin variants and prostate cancer risk and tumor aggressiveness. Human Molecular Genetics 2006;15:735-741.
*Jorgenson E, Witte JS. Coverage and power in genomewide association studies. American Journal of Human Genetics 2006;78:884-888.
*Nock NL, Cicek MS, Li L, Liu X, Rybicki BA, Moreira A, Plummer SJ, Casey G, Witte JS. Polymorphisms in estrogen bioactivation, detoxification and oxidative DNA base excision repair genes and prostate cancer risk. Carcinogenesis 2006;27:1842-1848.
Sapru A, Wiemels JL, Witte JS, Ware WB, Matthay MA. Acute Lung Injury and the Coagulation pathway: Potential role of gene polymorphisms in the protein C and fibrinolytic pathways. Intensive Care Medicine 2006;32:1293-1303.
*Cicek M, Liu X, Schumacher F, Casey G, Witte JS. Vitamin D receptor genotypes / haplotypes and prostate cancer risk and aggressiveness. Cancer Epidemiology, Biomarkers & Prevention 2006;15:2549-2552.
*Liu X, Plummer S, Casey G, Witte JS. Nonsteroidal anti-inflammatory drugs and advanced prostate cancer: modification by LTA+80. American Journal of Epidemiology 2006;164:984-989.
Tung JY, Rosen MP, Nelson LM, Turek PJ, Witte JS, Cramer DW, Cedars MI, Reijo Pera RA. Novel missense mutations of the Deleted-in-AZoospermia-Like (DAZL) gene in infertile women and men. Reproductive Biology and Endocrinology 2006;4:40.
*Jorgenson E, Witte JS. A gene-centric approach to genomewide association studies. Nature Reviews Genetics 2006,7:885-891.
*Liu X, Cicek MS, Plummer SJ, Jorgenson E, Casey G, Witte JS. Association of testis derived transcript gene variants and prostate cancer risk. J Urol. 2007;177:894-898.
*Cheng I, Plummer S, Casey GC, Witte JS. Toll-like Receptor 4 (TLR4) genetic variation and advanced prostate cancer risk. Cancer Epidemiology, Biomarkers & Prevention 2007;16:352-355.
*Liu X, Schumacher FR, Plummer SJ, Jorgenson E, Casey G, Witte JS. Trans fatty acid intake and increased risk of advanced prostate cancer: modification by RNASEL R462Q variant. Carcinogenesis 2007;28:1232-1236.
*Cheng I, Plummer S, Krumroy L, Casey GC, Witte JS. MIC1 and IL1RN genetic variation and advanced prostate cancer risk. Cancer Epidemiology, Biomarkers & Prevention 2007;16:352-355.
*Jorgenson E, Deitcher SR, Cicek M, Liu X, Casey G, Witte JS. Plasminogen activator inhibitor type-1 (PAI-1) polymorphism 4G/5G is associated with prostate cancer among men with a positive family history. Prostate 2007;67:172-177.
*Jorgenson EJ, Witte JS. Genome-wide association studies of cancer. Future Oncology 2007;3:419-427.
*Chen GK, Witte JS. Enriching the analysis of genome-wide association studies with hierarchical modeling. American Journal of Human Genetics 2007;81:397-404.
*Cheng I, Liu X, Plummer S, Krumroy LM, Casey GC, Witte JS. COX2 genetic variation, NSAIDs, and advanced prostate cancer risk. British Journal of Cancer 2007;97:557-61.
*Chen GK, Jorgenson E, Witte JS. An empirical evaluation of the common disease / common variant hypothesis. BMC Proceedings 2007;1:S5.
*Chen GK, Tien Z, Witte JS, Goode EL. Genome-wide association analyses of expression phenotypes. Genetic Epidemiology 2007;31:S7ÐS11.
*Cheng I, Plummer S, Jorgenson E, Casey G, Witte JS. 8q24 and prostate cancer: associated with advanced disease and meta-analysis. European Journal of Human Genetics 2008; European Journal of Human Genetics 2008;16:496-505.
*Cheng I, Witte JS. Toll-like receptor 4 and prostate cancer risk. Expert Opinion on Medical Diagnostics 2008;2:143-149.
1/8/09

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