Arturo Alvarez-Buylla, PhD

Arturo Alvarez-Buylla, PhD

Professor, Department of Neurological Surgery, UCSF
Heather and Melanie Muss Endowed Chair, UCSF

Phone: (415) 514-2348 (voice)
Box 0520, UCSF
San Francisco, CA 94143-0520

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Cancer Center Membership

Program Member » Neurologic Oncology


Physics, 1977-1978, Queens University, Kingston, Canada
UNAM, Mexico City, Licenciado, 1983, Bio-Medicine
Rockefeller University, Ph.D., 1988, Neurobiology
Rockefeller University, Postdoc, 1988-1989, Neurobiology

Professional Experience

  • 1983-1988
    Ph.D., Rockefeller University, New York
  • 1988-1989
    Postdoctoral Fellow, Rockefeller University
  • 1989-1992
    Assistant Professor, Rockefeller University
  • 1992-1994
    Assistant Professor/Head of Laboratory, Rockefeller University
  • 1994-2000
    Associate Professor/Head of Laboratory, Rockefeller University
  • 2000-2001
    Professor, Neurological Surgery, University of California, San Francisco
  • 2001-8/2003
    Stephen Muss Professor, Neurological Surgery, University of California, San Francisco
  • 9/2003-present
    Heather and Melanie Muss Endowed Chair, Neurological Surgery, University of California, San Francisco

Honors & Awards

  • 1983
    Medal Gavino Barreda -- Universidad Nacional Autonoma de Mexico
  • 1990
    First Award, The origin of new neurons in the adult avian brain
  • 1992
    Sinsheimer Award
  • 1994
    NIH-RO1 HD32116-01
  • 2000
    Jacob Javits Award, 2000/NIH Grant RO1 NS28478
  • 2001
    Brain Tumor Society. Are neural stem cells a source of brain tumors?
  • 2003
    NIH R01 HD032116-09. Origins of new neurons and glia in the postnatal brain
  • 2004
    Goldhirsh Foundation. Brain Tumor Research Grant 7/1/04 - 6/30/08.
  • 2006
    Catedra Santiago Grisolía, Spain. Lecture and Award
  • 2006
    "Académico Correspondiente Extranjero”. Real Academia de Ciencias Exactas, Físicas y Naturales. Spain
  • 2007
    Catedra Ramón y Cajal, Sociedad Española de Neurología, Spain
  • 2011
    Prince of Asturias Award for Technical and Scientific Research, Fundacíon Príncipe de Asturias, Spain. (Shared with Dr. Joseph Altman and Giacomo Rizzolatti)

Selected Publications

  1. Tong CK, Fuentealba LC, Shah JK, Lindquist RA, Ihrie RA, Guinto CD, Rodas-Rodriguez JL, Alvarez-Buylla A. A Dorsal SHH-Dependent Domain in the V-SVZ Produces Large Numbers of Oligodendroglial Lineage Cells in the Postnatal Brain. Stem Cell Reports. 2015 Oct 13; 5(4):461-70.
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  2. Harwell CC, Fuentealba LC, Gonzalez-Cerrillo A, Parker PR, Gertz CC, Mazzola E, Garcia MT, Alvarez-Buylla A, Cepko CL, Kriegstein AR. Wide Dispersion and Diversity of Clonally Related Inhibitory Interneurons. Neuron. 2015 Sep 2; 87(5):999-1007.
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  3. Fuentealba LC, Rompani SB, Parraguez JI, Obernier K, Romero R, Cepko CL, Alvarez-Buylla A. Embryonic Origin of Postnatal Neural Stem Cells. Cell. 2015 Jun 18; 161(7):1644-55.
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  4. Vogt D, Wu PR, Sorrells SF, Arnold C, Alvarez-Buylla A, Rubenstein JL. Viral-mediated Labeling and Transplantation of Medial Ganglionic Eminence (MGE) Cells for In Vivo Studies. J Vis Exp. 2015; (98).
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  5. Fu Y, Kaneko M, Tang Y, Alvarez-Buylla A, Stryker MP. A cortical disinhibitory circuit for enhancing adult plasticity. Elife. 2014; 4.
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  6. Tang Y, Stryker MP, Alvarez-Buylla A, Espinosa JS. Cortical plasticity induced by transplantation of embryonic somatostatin or parvalbumin interneurons. Proc Natl Acad Sci U S A. 2014 Dec 23; 111(51):18339-44.
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  7. Tate MC, Lindquist RA, Nguyen T, Sanai N, Barkovich AJ, Huang EJ, Rowitch DH, Alvarez-Buylla A. Postnatal growth of the human pons: A morphometric and immunohistochemical analysis. J Comp Neurol. 2015 Feb 15; 523(3):449-62.
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  8. Bayraktar OA, Fuentealba LC, Alvarez-Buylla A, Rowitch DH. Astrocyte development and heterogeneity. Cold Spring Harb Perspect Biol. 2015 Jan; 7(1):a020362.
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  9. Lim DA, Alvarez-Buylla A. Adult neural stem cells stake their ground. Trends Neurosci. 2014 Oct; 37(10):563-71.
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  10. Alvarez-Buylla A. Yoshiki Sasai (1962-2014). Nature. 2014 Sep 4; 513(7516):34.
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  11. Tong CK, Han YG, Shah JK, Obernier K, Guinto CD, Alvarez-Buylla A. Primary cilia are required in a unique subpopulation of neural progenitors. Proc Natl Acad Sci U S A. 2014 Aug 26; 111(34):12438-43.
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  12. Ohata S, Nakatani J, Herranz-Pérez V, Cheng J, Belinson H, Inubushi T, Snider WD, García-Verdugo JM, Wynshaw-Boris A, Alvarez-Buylla A. Loss of Dishevelleds disrupts planar polarity in ependymal motile cilia and results in hydrocephalus. Neuron. 2014 Aug 6; 83(3):558-71.
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  13. Tong LM, Djukic B, Arnold C, Gillespie AK, Yoon SY, Wang MM, Zhang O, Knoferle J, Rubenstein JL, Alvarez-Buylla A, Huang Y. Inhibitory interneuron progenitor transplantation restores normal learning and memory in ApoE4 knock-in mice without or with Aß accumulation. J Neurosci. 2014 Jul 16; 34(29):9506-15.
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  14. Obernier K, Tong CK, Alvarez-Buylla A. Restricted nature of adult neural stem cells: re-evaluation of their potential for brain repair. Front Neurosci. 2014; 8:162.
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  15. Alfaro-Cervello C, Cebrian-Silla A, Soriano-Navarro M, Garcia-Tarraga P, Matías-Guiu J, Gomez-Pinedo U, Molina Aguilar P, Alvarez-Buylla A, Luquin MR, Garcia-Verdugo JM. The adult macaque spinal cord central canal zone contains proliferative cells and closely resembles the human. J Comp Neurol. 2014 Jun 1; 522(8):1800-17.
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  16. Hwang WW, Salinas RD, Siu JJ, Kelley KW, Delgado RN, Paredes MF, Alvarez-Buylla A, Oldham MC, Lim DA. Distinct and separable roles for EZH2 in neurogenic astroglia. Elife. 2014; 3:e02439.
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  17. Southwell DG, Nicholas CR, Basbaum AI, Stryker MP, Kriegstein AR, Rubenstein JL, Alvarez-Buylla A. Interneurons from embryonic development to cell-based therapy. Science. 2014 Apr 11; 344(6180):1240622.
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  18. Tong CK, Chen J, Cebrián-Silla A, Mirzadeh Z, Obernier K, Guinto CD, Tecott LH, García-Verdugo JM, Kriegstein A, Alvarez-Buylla A. Axonal control of the adult neural stem cell niche. Cell Stem Cell. 2014 Apr 3; 14(4):500-11.
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  19. Tong CK, Alvarez-Buylla A. SnapShot: adult neurogenesis in the V-SVZ. Neuron. 2014 Jan 8; 81(1):220-220.e1.
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  20. Giachino C, Basak O, Lugert S, Knuckles P, Obernier K, Fiorelli R, Frank S, Raineteau O, Alvarez-Buylla A, Taylor V. Molecular diversity subdivides the adult forebrain neural stem cell population. Stem Cells. 2014 Jan; 32(1):70-84.
    View on PubMed

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