Arturo Alvarez-Buylla, PhD

Professor, Department of Neurological Surgery, UCSF
Heather and Melanie Muss Endowed Chair, UCSF

ABuylla@stemcell.ucsf.edu

Phone: (415) 514-2348 (voice)
Box 0520, UCSF
San Francisco, CA 94143-0520

View on UCSF Profiles

Education

Physics, 1977-1978, Queens University, Kingston, Canada
UNAM, Mexico City, Licenciado, 1983, Bio-Medicine
Rockefeller University, Ph.D., 1988, Neurobiology
Rockefeller University, Postdoc, 1988-1989, Neurobiology
 

Professional Experience

• 1983-1988
  Ph.D., Rockefeller University, New York
• 1988-1989
  Postdoctoral Fellow, Rockefeller University
• 1989-1992
  Assistant Professor, Rockefeller University
• 1992-1994
  Assistant Professor/Head of Laboratory, Rockefeller University
• 1994-2000
  Associate Professor/Head of Laboratory, Rockefeller University
• 2000-2001
  Professor, Neurological Surgery, University of California, San Francisco
• 2001-8/2003
  Stephen Muss Professor, Neurological Surgery, University of California, San Francisco
• 9/2003-present
  Heather and Melanie Muss Endowed Chair, Neurological Surgery, University of California, San Francisco

Honors & Awards

• 1983
  Medal Gavino Barreda -- Universidad Nacional Autonoma de Mexico
• 1990
  First Award, The origin of new neurons in the adult avian brain
• 1992
  Sinsheimer Award
• 1994
  NIH-RO1 HD32116-01
• 2000
  Jacob Javits Award, 2000/NIH Grant RO1 NS28478
• 2001
  Brain Tumor Society. Are neural stem cells a source of brain tumors?
• 2003
  NIH R01 HD032116-09. Origins of new neurons and glia in the postnatal brain
• 2004
  Goldhirsh Foundation. Brain Tumor Research Grant 7/1/04 - 6/30/08.
• 2006
  Catedra Santiago Grisolía, Spain. Lecture and Award
• 2006
  "Académico Correspondiente Extranjero”. Real Academia de Ciencias Exactas, Físicas y Naturales. Spain
• 2007
  Catedra Ramón y Cajal, Sociedad Española de Neurología, Spain
• 2011
  Prince of Asturias Award for Technical and Scientific Research, Fundacíon Príncipe de Asturias, Spain. (Shared with Dr. Joseph Altman and Giacomo Rizzolatti)

Selected Publications

1. Nicholas CR, Chen J, Tang Y, Southwell DG, Chalmers N, Vogt D, Arnold CM, Chen YJ, Stanley EG, Elefanty AG, Sasai Y, Alvarez-Buylla A, Rubenstein JL, Kriegstein AR. Functional Maturation of hPSC-Derived Forebrain Interneurons Requires an Extended Timeline and Mimics Human Neural Development. Cell Stem Cell. 2013 May 2; 12(5):573-86.
   View on PubMed
2. Chen YJ, Vogt D, Wang Y, Visel A, Silberberg SN, Nicholas CR, Danjo T, Pollack JL, Pennacchio LA, Anderson S, Sasai Y, Baraban SC, Kriegstein AR, Alvarez-Buylla A, Rubenstein JL. Use of "MGE Enhancers" for Labeling and Selection of Embryonic Stem Cell-Derived Medial Ganglionic Eminence (MGE) Progenitors and Neurons. PLoS One. 2013; 8(5):e61956.
   View on PubMed
3. Ponti G, Obernier K, Guinto C, Jose L, Bonfanti L, Alvarez-Buylla A. Cell cycle and lineage progression of neural progenitors in the ventricular-subventricular zones of adult mice. Proc Natl Acad Sci U S A. 2013 Mar 12; 110(11):E1045-54.
   View on PubMed
4. Plath K, Srivastava D, Alvarez-Buylla A, Tanaka EM, Kriegstein AR. Stem Cells in the Land of the Rising Sun: ISSCR 2012. Cell Stem Cell. 2012 Nov 2; 11(5):607-14.
   View on PubMed
5. Alfaro-Cervello C, Soriano-Navarro M, Mirzadeh Z, Alvarez-Buylla A, Garcia-Verdugo JM. Biciliated ependymal cell proliferation contributes to spinal cord growth. J Comp Neurol. 2012 Oct 15; 520(15):3528-52.
   View on PubMed
6. Southwell DG, Paredes MF, Galvao RP, Jones DL, Froemke RC, Sebe JY, Alfaro-Cervello C, Tang Y, Garcia-Verdugo JM, Rubenstein JL, Baraban SC, Alvarez-Buylla A. Intrinsically determined cell death of developing cortical interneurons. Nature. 2012 Nov 1; 491(7422):109-13.
   View on PubMed
7. Venere M, Han YG, Bell R, Song JS, Alvarez-Buylla A, Blelloch R. Sox1 marks an activated neural stem/progenitor cell in the hippocampus. Development. 2012 Nov; 139(21):3938-49.
   View on PubMed
8. Tsai HH, Li H, Fuentealba LC, Molofsky AV, Taveira-Marques R, Zhuang H, Tenney A, Murnen AT, Fancy SP, Merkle F, Kessaris N, Alvarez-Buylla A, Richardson WD, Rowitch DH. Regional astrocyte allocation regulates CNS synaptogenesis and repair. Science. 2012 Jul 20; 337(6092):358-62.
   View on PubMed
9. Fuentealba LC, Obernier K, Alvarez-Buylla A. Adult neural stem cells bridge their niche. Cell Stem Cell. 2012 Jun 14; 10(6):698-708.
   View on PubMed
10. Bráz JM, Sharif-Naeini R, Vogt D, Kriegstein A, Alvarez-Buylla A, Rubenstein JL, Basbaum AI. Forebrain GABAergic neuron precursors integrate into adult spinal cord and reduce injury-induced neuropathic pain. Neuron. 2012 May 24; 74(4):663-75.
    View on PubMed
11. Cage TA, Louie JD, Liu SR, Alvarez-Buylla A, Gupta N, Hyer J. Distinct patterns of human medulloblastoma dissemination in the developing chick embryo nervous system. Clin Exp Metastasis. 2012 Apr; 29(4):371-80.
    View on PubMed
12. Sanai N, Nguyen T, Ihrie RA, Mirzadeh Z, Tsai HH, Wong M, Gupta N, Berger MS, Huang E, Garcia-Verdugo JM, Rowitch DH, Alvarez-Buylla A. Corridors of migrating neurons in the human brain and their decline during infancy. Nature. 2011 Oct 20; 478(7369):382-6.
    View on PubMed
13. Ihrie RA, Shah JK, Harwell CC, Levine JH, Guinto CD, Lezameta M, Kriegstein AR, Alvarez-Buylla A. Persistent sonic hedgehog signaling in adult brain determines neural stem cell positional identity. Neuron. 2011 Jul 28; 71(2):250-62.
    View on PubMed
14. Ihrie RA, Alvarez-Buylla A. Lake-front property: a unique germinal niche by the lateral ventricles of the adult brain. Neuron. 2011 May 26; 70(4):674-86.
    View on PubMed
15. Sawamoto K, Hirota Y, Alfaro-Cervello C, Soriano-Navarro M, He X, Hayakawa-Yano Y, Yamada M, Hikishima K, Tabata H, Iwanami A, Nakajima K, Toyama Y, Itoh T, Alvarez-Buylla A, Garcia-Verdugo JM, Okano H. Cellular composition and organization of the subventricular zone and rostral migratory stream in the adult and neonatal common marmoset brain. J Comp Neurol. 2011 Mar 1; 519(4):690-713.
    View on PubMed
16. Gonzalez-Perez O, Alvarez-Buylla A. Oligodendrogenesis in the subventricular zone and the role of epidermal growth factor. Brain Res Rev. 2011 Jun 24; 67(1-2):147-56.
    View on PubMed
17. Kaneko N, Marín O, Koike M, Hirota Y, Uchiyama Y, Wu JY, Lu Q, Tessier-Lavigne M, Alvarez-Buylla A, Okano H, Rubenstein JL, Sawamoto K. New neurons clear the path of astrocytic processes for their rapid migration in the adult brain. Neuron. 2010 Jul 29; 67(2):213-23.
    View on PubMed
18. Mirzadeh Z, Doetsch F, Sawamoto K, Wichterle H, Alvarez-Buylla A. The subventricular zone en-face: wholemount staining and ependymal flow. J Vis Exp. 2010; (39).
    View on PubMed
19. Martínez-Cerdeño V, Noctor SC, Espinosa A, Ariza J, Parker P, Orasji S, Daadi MM, Bankiewicz K, Alvarez-Buylla A, Kriegstein AR. Embryonic MGE precursor cells grafted into adult rat striatum integrate and ameliorate motor symptoms in 6-OHDA-lesioned rats. Cell Stem Cell. 2010 Mar 5; 6(3):238-50.
    View on PubMed
20. Southwell DG, Froemke RC, Alvarez-Buylla A, Stryker MP, Gandhi SP. Cortical plasticity induced by inhibitory neuron transplantation. Science. 2010 Feb 26; 327(5969):1145-8.
    View on PubMed

View on UCSF Profiles