Daniel Lim, MD, PhD

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Daniel Lim, MD, PhD

Associate Professor of Neurological Surgery, UCSF

Daniel.Lim@ucsf.edu

Box 0525, UCSF
San Francisco, CA 94143

UCSF Profiles | Lab Website

Cancer Center Membership

Member » Neurologic Oncology

Education

  • University of California, Berkeley, B.A., 05/1994, Biochemistry
  • The Rockefeller University, Ph.D., 06/2001, Neurobiology
  • Cornell Medical College, M.D., 06/2002, Medicine
  • University of California, San Francisco, Postdoctoral, 06/2007, Epigenetics/Stem cells
  • University of California, San Francisco, Residency, 06/2008, Neurological Surgery

Professional Experience

  • 2008-2015
    Assistant Professor, UCSF
  • 2008-present
    Staff Neurosurgeon, Veteran’s Affairs Medical Center, San Francisco
  • 2008-present
    Faculty, Biomedical Sciences Graduate School Program (BMS), UCSF
  • 2008-present
    Faculty, Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, UCSF
  • 2008-present
    Director, Restorative Neurosurgery, Dept. of Neurological Surgery, UCSF
  • 2015-present
    Associate Professor, UCSF

Honors & Awards

  • 1990
    National Merit scholarship
  • 1990-1994
    University of California, Regent’s scholarship
  • 2009-2013
    Sontag Foundation Distinguished Researcher Award
  • 2009-2014
    NIH Director’s New Innovator Award
  • 2010
    Kavli Fellow, U.S. National Academy of Sciences

Selected Publications

  1. Liu SJ, Horlbeck MA, Cho SW, Birk HS, Malatesta M, He D, Attenello FJ, Villalta JE, Cho MY, Chen Y, Mandegar MA, Olvera MP, Gilbert LA, Conklin BR, Chang HY, Weissman JS, Lim DA. CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells. Science. 2016 Dec 15.
    View on PubMed
  2. Müller S, Liu SJ, Di Lullo E, Malatesta M, Pollen AA, Nowakowski TJ, Kohanbash G, Aghi M, Kriegstein AR, Lim DA, Diaz A. Single-cell sequencing maps gene expression to mutational phylogenies in PDGF- and EGF-driven gliomas. Mol Syst Biol. 2016 Nov 25; 12(11):889.
    View on PubMed
  3. Delgado RN, Lu C, Lim DA. Maintenance of neural stem cell regional identity in culture. Neurogenesis (Austin). 2016; 3(1):e1187321.
    View on PubMed
  4. Lim DA, Alvarez-Buylla A. The Adult Ventricular-Subventricular Zone (V-SVZ) and Olfactory Bulb (OB) Neurogenesis. Cold Spring Harb Perspect Biol. 2016; 8(5).
    View on PubMed
  5. Diaz A, Liu SJ, Sandoval C, Pollen A, Nowakowski TJ, Lim DA, Kriegstein A. SCell: integrated analysis of single-cell RNA-seq data. Bioinformatics. 2016 Jul 15; 32(14):2219-20.
    View on PubMed
  6. Liu SJ, Nowakowski TJ, Pollen AA, Lui JH, Horlbeck MA, Attenello FJ, He D, Weissman JS, Kriegstein AR, Diaz AA, Lim DA. Single-cell analysis of long non-coding RNAs in the developing human neocortex. Genome Biol. 2016; 17(1):67.
    View on PubMed
  7. Rowland NC, Kalia SK, Kalia LV, Larson PS, Lim DA, Bankiewicz KS. Merging DBS with viral vector or stem cell implantation: "hybrid" stereotactic surgery as an evolution in the surgical treatment of Parkinson's disease. Mol Ther Methods Clin Dev. 2016; 3:15051.
    View on PubMed
  8. Ramos AD, Attenello FJ, Lim DA. Uncovering the roles of long noncoding RNAs in neural development and glioma progression. Neurosci Lett. 2016 Jun 20; 625:70-9.
    View on PubMed
  9. Rolston JD, Ramos AD, Heath S, Englot DJ, Lim DA. Thalamotomy-Like Effects From Partial Removal of a Ventral Intermediate Nucleus Deep Brain Stimulator Lead in a Patient With Essential Tremor: Case Report. Neurosurgery. 2015 Nov; 77(5):E831-7.
    View on PubMed
  10. Pollen AA, Nowakowski TJ, Chen J, Retallack H, Sandoval-Espinosa C, Nicholas CR, Shuga J, Liu SJ, Oldham MC, Diaz A, Lim DA, Leyrat AA, West JA, Kriegstein AR. Molecular Identity of Human Outer Radial Glia during Cortical Development. Cell. 2015 Sep 24; 163(1):55-67.
    View on PubMed
  11. Delgado RN, Lim DA. Embryonic Nkx2.1-expressing neural precursor cells contribute to the regional heterogeneity of adult V-SVZ neural stem cells. Dev Biol. 2015 Nov 15; 407(2):265-74.
    View on PubMed
  12. Lim DA. Transcriptional and epigenetic insights from stem cells and developing tissues. Development. 2015 Aug 1; 142(15):2549-53.
    View on PubMed
  13. Ramos AD, Andersen RE, Liu SJ, Nowakowski TJ, Hong SJ, Gertz CC, Salinas RD, Zarabi H, Kriegstein AR, Lim DA. The long noncoding RNA Pnky regulates neuronal differentiation of embryonic and postnatal neural stem cells. Cell Stem Cell. 2015 Apr 2; 16(4):439-47.
    View on PubMed
  14. Rowland NC, Starr PA, Larson PS, Ostrem JL, Marks WJ, Lim DA. Combining cell transplants or gene therapy with deep brain stimulation for Parkinson's disease. Mov Disord. 2015 Feb; 30(2):190-5.
    View on PubMed
  15. Potts MB, Siu JJ, Price JD, Salinas RD, Cho MJ, Ramos AD, Hahn J, Margeta M, Oldham MC, Lim DA. Analysis of Mll1 deficiency identifies neurogenic transcriptional modules and Brn4 as a factor for direct astrocyte-to-neuron reprogramming. Neurosurgery. 2014 Oct; 75(4):472-82; discussion 482.
    View on PubMed
  16. Lim DA, Alvarez-Buylla A. Adult neural stem cells stake their ground. Trends Neurosci. 2014 Oct; 37(10):563-71.
    View on PubMed
  17. Price JD, Park KY, Chen J, Salinas RD, Cho MJ, Kriegstein AR, Lim DA. The Ink4a/Arf locus is a barrier to direct neuronal transdifferentiation. J Neurosci. 2014 Sep 10; 34(37):12560-7.
    View on PubMed
  18. Park DH, Hong SJ, Salinas RD, Liu SJ, Sun SW, Sgualdino J, Testa G, Matzuk MM, Iwamori N, Lim DA. Activation of neuronal gene expression by the JMJD3 demethylase is required for postnatal and adult brain neurogenesis. Cell Rep. 2014 Sep 11; 8(5):1290-9.
    View on PubMed
  19. Silvestrini MT, Yin D, Martin AJ, Coppes VG, Mann P, Larson PS, Starr PA, Zeng X, Gupta N, Panter SS, Desai TA, Lim DA. Interventional magnetic resonance imaging-guided cell transplantation into the brain with radially branched deployment. Mol Ther. 2015 Jan; 23(1):119-29.
    View on PubMed
  20. Andersen RE, Lim DA. An ingredient for the elixir of youth. Cell Res. 2014 Dec; 24(12):1381-2.
    View on PubMed

Go to UCSF Profiles, powered by CTSI