Susanna Rosi, PhD


Associate Professor, Director of Neurocognitive Research, Brain and Spinal Injury Center, BASIC

Additional Websites


University of Florence, Italy, B.S., 06/1995, Science
University of Florence, Italy, Ph.D., 06/2000, Biological Sciences
University of Florence, Italy, Postdoctoral, 2000-2001, Pharmacology
University of Arizona, Tucson, Arizona, Postdoctoral Research Associate , 2002-2006, Psychology

Professional Experience

  • 2000-2001
    Postdoctoral Fellow, University of Florence, Italy
  • 2002-2006
    Postdoctoral Research Associate, University of Arizona, Tucson, AZ
  • 2006-2011
    Assistant Professor, Departments of Physical Therapy Rehabilitation Science and Neurological Surgery, University of California, San Francisco, San Francisco, CA
  • 2011-present
    Associate Professor (1 year Accelerated), Departments of Physical Therapy Rehabilitation Science and Neurological Surgery, University of California, San Francisco, San Francisco.
  • 2011-present
    Director of Neurocognitive Research, Brain and Spinal Injury Center, University of California, San Francisco, San Francisco, CA

Honors & Awards

  • 1996-2000
    Graduate Fellowship, University of Florence, Italy

  • 2000
    Graduated with Distinction, University of Florence, Italy

  • 2001
    Postdoctoral Fellowship Award, Department of Pharmacology, University of Florence, Italy

  • 2004
    Travel Award, Winter Conference on Brain Research

  • 2006
    Special Award for Research and Career, “Vel l’Etrusco”, Castiglion Fiorentino, Arezzo, Italy

  • 2007
    UCSF, Academic Senate Committee on Research - Individual Investigator Award: seed funding

  • 2007
    UCSF, Research Evaluation and Allocation Committee Award: seed funding

  • 2007
    Tuscany Special Award “Young Talents and Magnificent Excellences”, Arezzo, Italy

  • 2008
    New Investigator Research Grant, Alzheimer’s Association

  • 2012
    UCSF, Department of Radiology and Biomedical Imaging, Seed Grant

Selected Publications

  1. Parihar VK, Allen BD, Tran KK, Chmielewski NN, Craver BM, Martirosian V, Morganti JM, Rosi S, Vlkolinsky R, Acharya MM, Nelson GA, Allen AR, Limoli CL. Targeted overexpression of mitochondrial catalase prevents radiation-induced cognitive dysfunction. Antioxid Redox Signal. 2015 Jan 1; 22(1):78-91.
    View on PubMed
  2. Allen AR, Eilertson K, Sharma S, Baure J, Allen B, Leu D, Rosi S, Raber J, Huang TT, Fike JR. Delayed administration of alpha-difluoromethylornithine prevents hippocampus-dependent cognitive impairment after single and combined injury in mice. Radiat Res. 2014 Nov; 182(5):489-98.
    View on PubMed
  3. Morganti JM, Jopson TD, Liu S, Gupta N, Rosi S. Cranial Irradiation Alters the Brain's Microenvironment and Permits CCR2+ Macrophage Infiltration. PLoS One. 2014; 9(4):e93650.
    View on PubMed
  4. Raber J, Rudobeck E, Campbell-Beachler M, Allen AR, Allen B, Rosi S, Nelson GA, Ramachandran S, Turner J, Fike JR, Vlkolinsky R. (28)Silicon radiation-induced enhancement of synaptic plasticity in the hippocampus of naïve and cognitively tested mice. Radiat Res. 2014 Apr; 181(4):362-8.
    View on PubMed
  5. Allen AR, Eilertson K, Chakraborti A, Sharma S, Baure J, Habdank-Kolaczkowski J, Allen B, Rosi S, Raber J, Fike JR. Radiation exposure prior to traumatic brain injury induces responses that differ as a function of animal age. Int J Radiat Biol. 2014 Mar; 90(3):214-23.
    View on PubMed
  6. Belarbi K, Rosi S. Modulation of adult-born neurons in the inflamed hippocampus. Front Cell Neurosci. 2013; 7:145.
    View on PubMed
  7. Allen AR, Eilertson K, Sharma S, Schneider D, Baure J, Allen B, Rosi S, Raber J, Fike JR. Effects of radiation combined injury on hippocampal function are modulated in mice deficient in chemokine receptor 2 (CCR2). Radiat Res. 2013 Jul; 180(1):78-88.
    View on PubMed
  8. Raber J, Allen AR, Rosi S, Sharma S, Dayger C, Davis MJ, Fike JR. Effects of (56)Fe radiation on hippocampal function in mice deficient in chemokine receptor 2 (CCR2). Behav Brain Res. 2013 Jun 1; 246:69-75.
    View on PubMed
  9. Raber J, Allen AR, Rosi S, Sharma S, Dayger C, Davis MJ, Fike JR. Effects of whole body (56)Fe radiation on contextual freezing and Arc-positive cells in the dentate gyrus. Behav Brain Res. 2013 Jun 1; 246:162-7.
    View on PubMed
  10. Ramirez-Amaya V, Angulo-Perkins A, Chawla MK, Barnes CA, Rosi S. Sustained transcription of the immediate early gene Arc in the dentate gyrus after spatial exploration. J Neurosci. 2013 Jan 23; 33(4):1631-9.
    View on PubMed
  11. Belarbi K, Jopson T, Arellano C, Fike JR, Rosi S. CCR2 deficiency prevents neuronal dysfunction and cognitive impairments induced by cranial irradiation. Cancer Res. 2013 Feb 1; 73(3):1201-10.
    View on PubMed
  12. Chakraborti A, Allen A, Allen B, Rosi S, Fike JR. Cranial irradiation alters dendritic spine density and morphology in the hippocampus. PLoS One. 2012; 7(7):e40844.
    View on PubMed
  13. Tweedie D, Ferguson RA, Fishman K, Frankola KA, Van Praag H, Holloway HW, Luo W, Li Y, Caracciolo L, Russo I, Barlati S, Ray B, Lahiri DK, Bosetti F, Greig NH, Rosi S. Tumor necrosis factor-a synthesis inhibitor 3,6'-dithiothalidomide attenuates markers of inflammation, Alzheimer pathology and behavioral deficits in animal models of neuroinflammation and Alzheimer's disease. J Neuroinflammation. 2012; 9:106.
    View on PubMed
  14. Rosi S, Ferguson R, Fishman K, Allen A, Raber J, Fike JR. The polyamine inhibitor alpha-difluoromethylornithine modulates hippocampus-dependent function after single and combined injuries. PLoS One. 2012; 7(1):e31094.
    View on PubMed
  15. Belarbi K, Jopson T, Tweedie D, Arellano C, Luo W, Greig NH, Rosi S. TNF-a protein synthesis inhibitor restores neuronal function and reverses cognitive deficits induced by chronic neuroinflammation. J Neuroinflammation. 2012; 9:23.
    View on PubMed
  16. Raber J, Rosi S, Chakraborti A, Fishman K, Dayger C, Davis MJ, Villasana L, Fike JR. Effects of 56Fe-particle cranial radiation on hippocampus-dependent cognition depend on the salience of the environmental stimuli. Radiat Res. 2011 Oct; 176(4):521-6.
    View on PubMed
  17. Belarbi K, Arellano C, Ferguson R, Jopson T, Rosi S. Chronic neuroinflammation impacts the recruitment of adult-born neurons into behaviorally relevant hippocampal networks. Brain Behav Immun. 2012 Jan; 26(1):18-23.
    View on PubMed
  18. Acharya MM, Christie LA, Lan ML, Giedzinski E, Fike JR, Rosi S, Limoli CL. Human neural stem cell transplantation ameliorates radiation-induced cognitive dysfunction. Cancer Res. 2011 Jul 15; 71(14):4834-45.
    View on PubMed
  19. Rosi S. Neuroinflammation and the plasticity-related immediate-early gene Arc. Brain Behav Immun. 2011 Jun; 25 Suppl 1:S39-49.
    View on PubMed
  20. Rosi S, Belarbi K, Ferguson RA, Fishman K, Obenaus A, Raber J, Fike JR. Trauma-induced alterations in cognition and Arc expression are reduced by previous exposure to 56Fe irradiation. Hippocampus. 2012 Mar; 22(3):544-54.
    View on PubMed

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