University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Javier Villanueva-Meyer, MD

Javier Villanueva-Meyer, MD

Assistant Professor of Clinical Radiology, UCSF

Cancer Center Program Memberships

Neurologic Oncology

Research Summary

Javier Villanueva­-Meyer, MD, is an Assistant Professor of Clinical Radiology in the Neuroradiology subspecialty section in the Department of Radiology and Biomedical Imaging at the University of California, San Francisco. He received his medical degree from Baylor College of Medicine in Houston, Texas, and he completed his one-year internship at Virginia Tech Carilion School of Medicine in Roanoke. Dr. Villanueva-­Meyer completed his four-year diagnostic radiology residency at the UCSF, followed by a Neuroradiology fellowship at UCSF. He also completed a NIH T32 post-doctoral fellowship in the UCSF Department of Radiology and Biomedical Imaging.

Dr. Villanueva-Meyer’s interests focus on advanced MR imaging and imaging based tools to better delineate and characterize brain tumors. His research also involves molecular imaging where he works with collaborators within and outside of our department to develop and implement the use of PET radiotracers in both brain tumors and spinal infection.

Dr. Villanueva­-Meyer has experience in CT, MRI and plain film radiography of the brain, head and neck, spine, and peripheral nervous system in both the inpatient and outpatient settings. As well as diagnostic and therapeutic neuroradiology procedures, including percutaneous biopsy, lumbar puncture, myelography, cisternography, epidural and selective nerve root injection.

Expertise:

Neuroradiology

Specialty:

Brain Tumor Radiology

Professional Interests:

MRI of brain tumors, imaging of infection, molecular imaging

Education

  • Texas Tech University, Lubbock TX, B.B.A., 06/2007, Management
  • Baylor College of Medicine, Houston TX, M.D., 06/2011, Medicine
  • Virginia Tech Carilion, Roanoke VA, 06/2012, Internship
  • Dept of Radiology, UCSF Medical Center, San Francisco, CA, 06/2016, Radiology Residency
  • Dept of Radiology, UCSF Medical Center, San Francisco, CA, 06/2017, Neuroradiology Fellowship

Professional Experience

  • 2012 - 2016
    Diagnostic Radiology Resident, UCSF Radiology and Biomedical Imaging
  • 2016 - 2017
    ACGME Fellow, Neuroradiology, UCSF Radiology and Biomedical Imaging
  • 2017 - present
    Assistant Professor of Radiology, UCSF Radiology and Biomedical Imaging

Honors & Awards

  • 2007
    Summa cum laude, Texas Tech University
  • 2007
    Full merit scholarship, Baylor College of Medicine
  • 2013
    Margulis Society Resident Research Award, UCSF
  • 2014
    AUR Radiology Resident Academic Leadership Development Grant
  • 2015
    Chief Resident, Diagnostic Radiology Residency Program, UCSF
  • 2016
    ACR - AUR Research Scholar
  • 2016
    NIH - NIBIB T32 Research Grant Fellow
  • 2016
    Outstanding Podium Presentation, Imaging Research Symposium, UCSF
  • 2016
    Elmer Ng MD Award for Outstanding Resident in Diagnostic Radiology, UCSF
  • 2017
    Trainee Award, American Society of Neuroradiology
  • 2018
    John A. Watson Scholar, UCSF

Selected Publications

  1. Dalle Ore CL, Magill ST, Rodriguez Rubio R, Shahin MN, Aghi MK, Theodosopoulos PV, Villanueva-Meyer JE, Kersten RC, Idowu OO, Vagefi MR, McDermott MW. Hyperostosing sphenoid wing meningiomas: surgical outcomes and strategy for bone resection and multidisciplinary orbital reconstruction. J Neurosurg. 2020 Mar 06; 1-10.
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  2. Molinaro AM, Hervey-Jumper S, Morshed RA, Young J, Han SJ, Chunduru P, Zhang Y, Phillips JJ, Shai A, Lafontaine M, Crane J, Chandra A, Flanigan P, Jahangiri A, Cioffi G, Ostrom Q, Anderson JE, Badve C, Barnholtz-Sloan J, Sloan AE, Erickson BJ, Decker PA, Kosel ML, LaChance D, Eckel-Passow J, Jenkins R, Villanueva-Meyer J, Rice T, Wrensch M, Wiencke JK, Oberheim Bush NA, Taylor J, Butowski N, Prados M, Clarke J, Chang S, Chang E, Aghi M, Theodosopoulos P, McDermott M, Berger MS. Association of Maximal Extent of Resection of Contrast-Enhanced and Non-Contrast-Enhanced Tumor With Survival Within Molecular Subgroups of Patients With Newly Diagnosed Glioblastoma. JAMA Oncol. 2020 Feb 06.
    View on PubMed
  3. Liu SJ, Magill ST, Vasudevan HN, Hilz S, Villanueva-Meyer JE, Lastella S, Daggubati V, Spatz J, Choudhury A, Orr BA, Demaree B, Seo K, Ferris SP, Abate AR, Oberheim Bush NA, Bollen AW, McDermott MW, Costello JF, Raleigh DR. Multiplatform Molecular Profiling Reveals Epigenomic Intratumor Heterogeneity in Ependymoma. Cell Rep. 2020 Feb 04; 30(5):1300-1309.e5.
    View on PubMed
  4. Lee JC, Villanueva-Meyer JE, Ferris SP, Cham EM, Zucker J, Cooney T, Gilani A, Kleinschmidt-DeMasters BK, Trembath D, Mafra M, Chiang J, Ellison DW, Cho SJ, Horvai AE, Van Ziffle J, Onodera C, Devine P, Grenert JP, de Voijs CMA, van Blokland WTM, de Leng WWJ, Ploegmakers MJ, Flucke U, Pekmezci M, Bollen AW, Tihan T, Koelsche C, von Deimling A, Wesseling P, Solomon DA, Perry A. Clinicopathologic and molecular features of intracranial desmoplastic small round cell tumors. Brain Pathol. 2019 Dec 14.
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  5. Stewart MN, Parker MFL, Jivan S, Luu JM, Huynh TL, Schulte B, Seo Y, Blecha JE, Villanueva-Meyer JE, Flavell RR, VanBrocklin HF, Ohliger MA, Rosenberg O, Wilson DM. High Enantiomeric Excess In-Loop Synthesis of d-[methyl-11C]Methionine for Use as a Diagnostic Positron Emission Tomography Radiotracer in Bacterial Infection. ACS Infect Dis. 2020 Jan 10; 6(1):43-49.
    View on PubMed
  6. Alcaide-Leon P, Luks TL, Lafontaine M, Lupo JM, Okada H, Clarke JL, Villanueva-Meyer JE. Treatment-induced lesions in newly diagnosed glioblastoma patients undergoing chemoradiotherapy and heat-shock protein vaccine therapy. J Neurooncol. 2020 Jan; 146(1):71-78.
    View on PubMed
  7. Lucas CG, Villanueva-Meyer JE, Whipple N, Oberheim Bush NA, Cooney T, Chang S, McDermott M, Berger M, Cham E, Sun PP, Putnam A, Zhou H, Bollo R, Cheshier S, Poppe MM, Fung KM, Sung S, Glenn C, Fan X, Bannykh S, Hu J, Danielpour M, Li R, Alva E, Johnston J, Van Ziffle J, Onodera C, Devine P, Grenert JP, Lee JC, Pekmezci M, Tihan T, Bollen AW, Perry A, Solomon DA. Myxoid glioneuronal tumor, PDGFRA p.K385-mutant: clinical, radiologic, and histopathologic features. Brain Pathol. 2019 Oct 14.
    View on PubMed
  8. Chen Y, Villanueva-Meyer JE, Morrison MA, Lupo JM. Correction to: Toward Automatic Detection of Radiation-Induced Cerebral Microbleeds Using a 3D Deep Residual Network. J Digit Imaging. 2019 Oct; 32(5):898.
    View on PubMed
  9. Chen Y, Villanueva-Meyer JE, Morrison MA, Lupo JM. Toward Automatic Detection of Radiation-Induced Cerebral Microbleeds Using a 3D Deep Residual Network. J Digit Imaging. 2019 Oct; 32(5):766-772.
    View on PubMed
  10. Morin O, Chen WC, Nassiri F, Susko M, Magill ST, Vasudevan HN, Wu A, Vallières M, Gennatas ED, Valdes G, Pekmezci M, Alcaide-Leon P, Choudhury A, Interian Y, Mortezavi S, Turgutlu K, Bush NAO, Solberg TD, Braunstein SE, Sneed PK, Perry A, Zadeh G, McDermott MW, Villanueva-Meyer JE, Raleigh DR. Integrated models incorporating radiologic and radiomic features predict meningioma grade, local failure, and overall survival. Neurooncol Adv. 2019 May-Dec; 1(1):vdz011.
    View on PubMed
  11. Bucknor MD, Villanueva-Meyer JE, Kumar V, Talbott JF, Wall SD, Glastonbury CM, Dillon WP, Arenson RL, Wilson MW, Hess CP. Diversity and Inclusion Efforts in University of California, San Francisco Radiology: Reflections on 3 Years of Pipeline, Selection, and Education Initiatives. J Am Coll Radiol. 2019 Dec; 16(12):1716-1719.
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  12. Dalle Ore CL, Magill ST, Yen AJ, Shahin MN, Lee DS, Lucas CG, Chen WC, Viner JA, Aghi MK, Theodosopoulos PV, Raleigh DR, Villanueva-Meyer JE, McDermott MW. Meningioma metastases: incidence and proposed screening paradigm. J Neurosurg. 2019 Apr 05; 1-9.
    View on PubMed
  13. Wang ZJ, Ohliger MA, Larson PEZ, Gordon JW, Bok RA, Slater J, Villanueva-Meyer JE, Hess CP, Kurhanewicz J, Vigneron DB. Hyperpolarized 13C MRI: State of the Art and Future Directions. Radiology. 2019 05; 291(2):273-284.
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  14. Baal JD, Chen WC, Solomon DA, Pai JS, Lucas CH, Hara JH, Oberheim Bush NA, McDermott MW, Raleigh DR, Villanueva-Meyer JE. Preoperative MR Imaging to Differentiate Chordoid Meningiomas from Other Meningioma Histologic Subtypes. AJNR Am J Neuroradiol. 2019 03; 40(3):433-439.
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  15. Lee JC, Villanueva-Meyer JE, Ferris SP, Sloan EA, Hofmann JW, Hattab EM, Williams BJ, Guo H, Torkildson J, Florez A, Van Ziffle J, Onodera C, Grenert JP, Cho SJ, Horvai AE, Jones DTW, Pfister SM, Koelsche C, von Deimling A, Korshunov A, Perry A, Solomon DA. Primary intracranial sarcomas with DICER1 mutation often contain prominent eosinophilic cytoplasmic globules and can occur in the setting of neurofibromatosis type 1. Acta Neuropathol. 2019 03; 137(3):521-525.
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  16. Villanueva-Meyer JE, Chang P, Lupo JM, Hess CP, Flanders AE, Kohli M. Machine Learning in Neurooncology Imaging: From Study Request to Diagnosis and Treatment. AJR Am J Roentgenol. 2019 01; 212(1):52-56.
    View on PubMed
  17. Behr SC, Villanueva-Meyer JE, Li Y, Wang YH, Wei J, Moroz A, Lee JK, Hsiao JC, Gao KT, Ma W, Cha S, Wilson DM, Seo Y, Nelson SJ, Chang SM, Evans MJ. Targeting iron metabolism in high-grade glioma with 68Ga-citrate PET/MR. JCI Insight. 2018 11 02; 3(21).
    View on PubMed
  18. Villanueva-Meyer JE, Magill ST, Lee JC, Umetsu SE, Flavell RR. Detection of Metastatic Meningioma to the Liver Using 68Ga-DOTA-Octreotate PET/CT. Clin Nucl Med. 2018 Sep; 43(9):e338-e340.
    View on PubMed
  19. Morin O, Vallières M, Jochems A, Woodruff HC, Valdes G, Braunstein SE, Wildberger JE, Villanueva-Meyer JE, Kearney V, Yom SS, Solberg TD, Lambin P. A Deep Look Into the Future of Quantitative Imaging in Oncology: A Statement of Working Principles and Proposal for Change. Int J Radiat Oncol Biol Phys. 2018 11 15; 102(4):1074-1082.
    View on PubMed
  20. Solomon DA, Korshunov A, Sill M, Jones DTW, Kool M, Pfister SM, Fan X, Bannykh S, Hu J, Danielpour M, Li R, Johnston J, Cham E, Cooney T, Sun PP, Oberheim Bush NA, McDermott M, Van Ziffle J, Onodera C, Grenert JP, Bastian BC, Villanueva-Meyer JE, Pekmezci M, Bollen AW, Perry A. Myxoid glioneuronal tumor of the septum pellucidum and lateral ventricle is defined by a recurrent PDGFRA p.K385 mutation and DNT-like methylation profile. Acta Neuropathol. 2018 08; 136(2):339-343.
    View on PubMed

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