Precision Imaging of Cancer and Therapy Program

B.FrancS.RonenS.Nelson Program Director: Sarah Nelson, PhD
Associate Director: Sabrina Ronen, PhD
Associate Director: Benjamin Franc, MD

 

The PICT Program brings together basic, translational and clinical scientists in order to integrate cutting edge, multi-modality imaging into all aspects of patient care and cancer research. By using novel imaging technologies and sophisticated data analysis tools to elucidate the underlying mechanisms of malignant transformation and drug resistance, it is possible to obtain a more precise understanding of disease progression and response to therapy. This is critical for identifying imaging phenotypes that will allow oncologists to tailor treatment strategies to specific tumor characteristics and provide improved outcomes.

The PICT Program conducts research under four themes:

  • Theme 1: Integrating quantitative imaging into clinical studies for stratifying cancer patients into more uniform subgroups and to provide objective metrics of response to therapy
  • Theme 2: Developing novel multi-parametric image acquisition methods and computational tools for quantitative data analysis for characterizing disease and assessing outcomes
  • Theme 3: Providing a pathway for studying the interplay between non-invasive imaging parameters and genomic data
  • Theme 4: Accelerating the pre-clinical testing of new therapies by developing companion imaging biomarkers to directly monitor their impact upon specific molecular targets at the earliest possible time point
  • Theme 5: Providing molecular imaging probes for studying the biological mechanisms of oncogenesis and metastasis

The PICT Program forms a bridge between the Radiology & Biomedical Imaging (RBI) and HDFCCC that takes advantage of natural synergies between them. Both organizations have clinical and research components that are organ, biology or technology focused, as well as an extensive repertoire of core facilities. A major goal of the PICT program is to encourage its members to develop new research partnerships and provide them with seamless access to core resources for pursuing their scientific and clinical goals. The Biomedical Imaging Research Support Services provides PICT with imaging resources to ensure research is conducted to its full potential.

Leadership:

Sarah Nelson – Director
Sabrina Ronen – Associate Director
Benjamin Franc – Associate Director

Imaging Program Manager:

Emma Bahroos – The point person to start collaborations

Scientific Advisory Committee: 

Rosemary Akhurst
Spencer Behr
Nicholas Butowski
Albert Chang
Charles Craik
Michael Evans
Lawrence Fong
John Kurhanewicz
Daniel Vigneron