Cancer Imaging Research

The mission of this shared resource is to provide members of the HDFCCC with technical capabilities and scientific expertise for integrating cutting-edge, multi-modality imaging into their basic, translational, and clinical research.


Pre-Clinical Imaging Core Services

  • Access to NMR systems for analysis of cell and tissue samples
  • Access to MR, PET and SPECT scanners for imaging small animals:
    • 500 MHz HR-MAS Spectrometer
    • 600 MHz Wide Bore HR-MAS/Micro-imaging Spectrometer
    • HyperSense DNP Polarizer
    • GE SpinLab Polarizer
    • Bruker BioSpecĀ® 3T Cryogen Free Pre-clinical MRI
    • Small animal SPECT/ PET/ CT Imager
    • MicroPET/CT Imager
    • Optical Bioluminescence and Fluorescence Imaging
    • Fluorescence Molecular Tomography (FMT
  • Resources for synthesizing radiolabeled and hyperpolarized imaging agents

Human Imaging Core Services

  • Access to polarizers and cyclotron for the synthesis of standard and experimental imaging agents.
    • GE 5T SpinLab multi-sample polarizer
    • Custom Compounding Aseptic Isolator Radial Laser Welders
    • PETtrace Medical cyclotron
    • Whole body MRI:
    • 3T MR750 and a 7T MR950 systems
    • 3T MR750 wide bore magnet
    • 1.5T MRI
    • InSightec ExAblate MR-guided Focused Ultrasound (MRgFUS) system is installed at the 3T MRI scanner
    • Quantitative high res extremity CT
    • Interventional 1.5T MRI
  • Expert assistance in developing, implementing and interpreting multi-modality imaging studies.
  • Collaboration with imaging scientists to translate novel imaging technologies to patients

Clinical Imaging Cores Services

  • Standard and specialized radiological interpretation, including Response Evaluation Criteria in Solid Tumors (RECIST) reads
  • Access to clinical scanners for in-patient and out-patient research studies.
    • Whole body PET/CT scanners with 16 & 64 Slice CT
    • SPECT/CT
    • PET/MR
    • Whole boday 1.5T & 3T MRI scanners
    • Whole body CT scanners with 64 & 256 slice
    • Ultrasound
    • X-rays
    • Imaging research coordinators
    • PETtrace Medical Cyclotron
  • Assessment of feasibility and implementation of imaging protocols for clinical trials
  • Image processing, data management and transfer between internal and external sources

Scientific Computing Services

  • Systems administration, hardware and software support
  • Storage and management of large imaging datasets and related data
  • Development of new algorithms for reconstruction and post-processing
  • Access to custom designed and open source packages for analyzing imaging studies
    • System Management
    • Applications Programming
    • Shared Software Packages
    • Access to: HP Computing Grids
  • Collaborations with imaging scientists interested in machine learning applications