Research Summary

I am a physician-scientist with a PhD in Cancer Biology and subspecialty medical training in Endocrinology. I have established a broadly recognized international reputation for high-impact and cutting-edge research. My laboratory has a long-standing interest in understanding the role of hormonal signals on cancer. We aim to develop novel preventative and therapeutic approaches based on the insights gained from revealing the molecular mechanisms of these pathways.

Research Funding

  • March 5, 2019 - May 31, 2022 - Integrated Systemic and Adipose Depot-Specific Regulation of Adipogenesis, Principal Investigator. Sponsor: NIH/NIDDK, Sponsor Award ID: R01DK114217
  • September 30, 2010 - June 30, 2015 - Using Components of the Circadian Clock to Regulate Stem Cell Fate Decisions, Principal Investigator. Sponsor: NIH, Sponsor Award ID: DP2OD006740
  • July 1, 2006 - June 30, 2011 - The Role of Glucocorticoids in Cell Fate Determination, Principal Investigator. Sponsor: NIH/NIDDK, Sponsor Award ID: K08DK073697
  • March 5, 2019 - May 31, 2022 - Integrated Systemic and Adipose Depot-Specific Regulation of Adipogenesis, Principal Investigator. Sponsor: NIH/NIDDK, Sponsor Award ID: R01DK114217

Education

Brandeis University, Waltham, MA B.A. 06/1993 Political Science
Stanford University, Stanford, CA M.D. 06/2001 Medicine
Stanford University, Stanford, CA Ph.D. 06/2001 Cancer Biology
Harvard University, Boston, MA 07/2004 Pediatric Residency
UCSF, San Francisco, CA 07/2006 Pediatric Endocrinology Fellowship

Honors & Awards

  • 2002
    Von Meyer Scholar Award (Harvard University)
  • 2006
    NIH K08 Career Development Grant (NIDDK)
  • 2007
    Lawson Wilkins Clinical Scholar Award (Pediatric Endocrine Society)
  • 2008
    Young Investigator Award (Society for Pediatric Research)
  • 2010
    NIH Director's New Innovator Award
  • 2011
    Harvey Cohen Lectureship (Stanford University)
  • 2012-2018
    Bechtel Endowed Faculty Scholar (Stanford University)
  • 2013
    Early Investigator Award (Endocrine Society)
  • 2014-2018
    SPARK Scholar
  • 2016
    International Scientific Advisory Committee for Vitamin D Research
  • 2016
    Basic Science Research Award of Excellence (Stanford University)
  • 2017
    Elected Member, The American Society for Clinical Investigation (ASCI)
  • 2018
    Jack Omdahl Lectureship (University of New Mexico)
  • 2018-present
    Walter L. Miller Distinguished Professorship in Pediatric Endocrinology

Selected Publications

  1. Huang Y, Zhao N, Wang YH, Truillet C, Wei J, Blecha JE, VanBrocklin HF, Seo Y, Sayeed M, Feldman BJ, Aggarwal R, Behr SC, Shao H, Wilson DM, Villanueva-Meyer JE, Gestwicki JE, Evans MJ A Novel Radioligand Reveals Tissue Specific Pharmacological Modulation of Glucocorticoid Receptor Expression with Positron Emission Tomography.  View on PubMed
  2. Carter KL, Treurnicht A, Davis KL, Kumar RB, Feldman BJ A novel platform for isotype-specific testing of autoantibodies.  View on PubMed
  3. Jung Y, Feldman BJ A context-specific circadian clock in adipocyte precursor cells modulates adipogenesis.  View on PubMed
  4. Aggarwal A, Costa MJ, Rivero-Gutiérrez B, Ji L, Morgan SL, Feldman BJ The Circadian Clock Regulates Adipogenesis by a Per3 Crosstalk Pathway to Klf15.  View on PubMed
  5. Du H, Shih CH, Wosczyna MN, Mueller AA, Cho J, Aggarwal A, Rando TA, Feldman BJ Macrophage-released ADAMTS1 promotes muscle stem cell activation.  View on PubMed
  6. Wong JC, Feldman BJ Adamts1 responds to systemic cues and gates adipogenesis.  View on PubMed
  7. Aggarwal A, Feldman D, Feldman BJ Identification of tumor-autonomous and indirect effects of vitamin D action that inhibit breast cancer growth and tumor progression.  View on PubMed
  8. Chen PI, Cao A, Miyagawa K, Tojais NF, Hennigs JK, Li CG, Sweeney NM, Inglis AS, Wang L, Li D, Ye M, Feldman BJ, Rabinovitch M Amphetamines promote mitochondrial dysfunction and DNA damage in pulmonary hypertension.  View on PubMed
  9. Wong JC, Krueger KC, Costa MJ, Aggarwal A, Du H, McLaughlin TL, Feldman BJ A glucocorticoid- and diet-responsive pathway toggles adipocyte precursor cell activity in vivo.  View on PubMed
  10. Williams JD, Aggarwal A, Swami S, Krishnan AV, Ji L, Albertelli MA, Feldman BJ Tumor Autonomous Effects of Vitamin D Deficiency Promote Breast Cancer Metastasis.  View on PubMed
  11. Swami S, Krishnan AV, Williams J, Aggarwal A, Albertelli MA, Horst RL, Feldman BJ, Feldman D Vitamin D mitigates the adverse effects of obesity on breast cancer in mice.  View on PubMed
  12. Ji L, Gupta M, Feldman BJ Vitamin D Regulates Fatty Acid Composition in Subcutaneous Adipose Tissue Through Elovl3.  View on PubMed
  13. Banerjee RR, Marina N, Katznelson L, Feldman BJ Mifepristone Treatment of Cushing's Syndrome in a Pediatric Patient.  View on PubMed
  14. Jeong Y, Swami S, Krishnan AV, Williams JD, Martin S, Horst RL, Albertelli MA, Feldman BJ, Feldman D, Diehn M Inhibition of Mouse Breast Tumor-Initiating Cells by Calcitriol and Dietary Vitamin D.  View on PubMed
  15. Diebold I, Hennigs JK, Miyagawa K, Li CG, Nickel NP, Kaschwich M, Cao A, Wang L, Reddy S, Chen PI, Nakahira K, Alcazar MA, Hopper RK, Ji L, Feldman BJ, Rabinovitch M BMPR2 preserves mitochondrial function and DNA during reoxygenation to promote endothelial cell survival and reverse pulmonary hypertension.  View on PubMed
  16. Ota A, Kovary KM, Wu OH, Ahrends R, Shen WJ, Costa MJ, Feldman BJ, Kraemer FB, Teruel MN Using SRM-MS to quantify nuclear protein abundance differences between adipose tissue depots of insulin-resistant mice.  View on PubMed
  17. Chao CS, McKnight KD, Cox KL, Chang AL, Kim SK, Feldman BJ Novel GATA6 mutations in patients with pancreatic agenesis and congenital heart malformations.  View on PubMed
  18. Kumar RB, Gupta M, Feldman BJ The development of next-generation screening and diagnostic platforms will change diabetes care.  View on PubMed
  19. Krueger KC, Costa MJ, Du H, Feldman BJ Characterization of Cre recombinase activity for in vivo targeting of adipocyte precursor cells.  View on PubMed
  20. Zhang B, Kumar RB, Dai H, Feldman BJ A plasmonic chip for biomarker discovery and diagnosis of type 1 diabetes.  View on PubMed

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