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An intramolecular cyclization reaction is responsible for the in vivo inefficacy and apparent pH insensitive hydrolysis kinetics of hydrazone carboxylate derivatives of doxorubicin.

Author List
Lee CC, Cramer AT, Szoka FC, Fréchet JM
Publication
Bioconjugate chemistry
Publication ID (Profile URL)
https://researcherprofiles.org/profile/1451884
Publication Year
2006
PubMed ID
16984149
Publication Title
Lee CC, Cramer AT, Szoka FC, Fréchet JM. An intramolecular cyclization reaction is responsible for the in vivo inefficacy and apparent pH insensitive hydrolysis kinetics of hydrazone carboxylate derivatives of doxorubicin. Bioconjug Chem. 2006 Sep-Oct; 17(5):1364-8.