Drug modulation of water-heme interactions in low-spin P450 complexes of CYP2C9d and CYP125A1. Read more about Drug modulation of water-heme interactions in low-spin P450 complexes of CYP2C9d and CYP125A1.
Broad-spectrum allosteric inhibition of herpesvirus proteases. Read more about Broad-spectrum allosteric inhibition of herpesvirus proteases.
Deconstructing signaling in three dimensions. Read more about Deconstructing signaling in three dimensions.
Identification of minimal HDV-like ribozymes with unique divalent metal ion dependence in the human microbiome. Read more about Identification of minimal HDV-like ribozymes with unique divalent metal ion dependence in the human microbiome.
Strength of axial water ligation in substrate-free cytochrome P450s is isoform dependent. Read more about Strength of axial water ligation in substrate-free cytochrome P450s is isoform dependent.
The E3 ubiquitin ligase CHIP and the molecular chaperone Hsc70 form a dynamic, tethered complex. Read more about The E3 ubiquitin ligase CHIP and the molecular chaperone Hsc70 form a dynamic, tethered complex.
Peroxisome proliferation-activated receptor δ agonist GW0742 interacts weakly with multiple nuclear receptors, including the vitamin D receptor. Read more about Peroxisome proliferation-activated receptor δ agonist GW0742 interacts weakly with multiple nuclear receptors, including the vitamin D receptor.
Mapping inhibitor binding modes on an active cysteine protease via nuclear magnetic resonance spectroscopy. Read more about Mapping inhibitor binding modes on an active cysteine protease via nuclear magnetic resonance spectroscopy.
Covalent attachment of heme to the protein moiety in an insect E75 nitric oxide sensor. Read more about Covalent attachment of heme to the protein moiety in an insect E75 nitric oxide sensor.
Ultrafast ligand dynamics in the heme-based GAF sensor domains of the histidine kinases DosS and DosT from Mycobacterium tuberculosis. Read more about Ultrafast ligand dynamics in the heme-based GAF sensor domains of the histidine kinases DosS and DosT from Mycobacterium tuberculosis.