Biguanides antithetically regulate tumor properties by the dose-dependent mitochondrial reprogramming-driven c-Src pathway. Read more about Biguanides antithetically regulate tumor properties by the dose-dependent mitochondrial reprogramming-driven c-Src pathway.
Multi-platform biomarkers of response to an immune checkpoint inhibitor in the neoadjuvant I-SPY 2 trial for early-stage breast cancer. Read more about Multi-platform biomarkers of response to an immune checkpoint inhibitor in the neoadjuvant I-SPY 2 trial for early-stage breast cancer.
Artificial intelligence, ChatGPT, and other large language models for social determinants of health: Current state and future directions. Read more about Artificial intelligence, ChatGPT, and other large language models for social determinants of health: Current state and future directions.
Protein signaling and drug target activation signatures to guide therapy prioritization: Therapeutic resistance and sensitivity in the I-SPY 2 Trial. Read more about Protein signaling and drug target activation signatures to guide therapy prioritization: Therapeutic resistance and sensitivity in the I-SPY 2 Trial.
Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML. Read more about Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML.
High-throughput chemogenetic drug screening reveals PKC-RhoA/PKN as a targetable signaling vulnerability in GNAQ-driven uveal melanoma. Read more about High-throughput chemogenetic drug screening reveals PKC-RhoA/PKN as a targetable signaling vulnerability in GNAQ-driven uveal melanoma.
Tumor biology and immune infiltration define primary liver cancer subsets linked to overall survival after immunotherapy. Read more about Tumor biology and immune infiltration define primary liver cancer subsets linked to overall survival after immunotherapy.
Nucleic acid biomarkers of immune response and cell and tissue damage in children with COVID-19 and MIS-C. Read more about Nucleic acid biomarkers of immune response and cell and tissue damage in children with COVID-19 and MIS-C.
Development of an artificial intelligence-derived histologic signature associated with adjuvant gemcitabine treatment outcomes in pancreatic cancer. Read more about Development of an artificial intelligence-derived histologic signature associated with adjuvant gemcitabine treatment outcomes in pancreatic cancer.
A single-cell transcriptional gradient in human cutaneous memory T cells restricts Th17/Tc17 identity. Read more about A single-cell transcriptional gradient in human cutaneous memory T cells restricts Th17/Tc17 identity.
