SDHB knockout and succinate accumulation are insufficient for tumorigenesis but dual SDHB/NF1 loss yields SDHx-like pheochromocytomas. Read more about SDHB knockout and succinate accumulation are insufficient for tumorigenesis but dual SDHB/NF1 loss yields SDHx-like pheochromocytomas.
LGL1 binds to Integrin β1 and inhibits downstream signaling to promote epithelial branching in the mammary gland. Read more about LGL1 binds to Integrin β1 and inhibits downstream signaling to promote epithelial branching in the mammary gland.
Targetable HER3 functions driving tumorigenic signaling in HER2-amplified cancers. Read more about Targetable HER3 functions driving tumorigenic signaling in HER2-amplified cancers.
Extensive conformational and physical plasticity protects HER2-HER3 tumorigenic signaling. Read more about Extensive conformational and physical plasticity protects HER2-HER3 tumorigenic signaling.
Phage-delivered CRISPR-Cas9 for strain-specific depletion and genomic deletions in the gut microbiome. Read more about Phage-delivered CRISPR-Cas9 for strain-specific depletion and genomic deletions in the gut microbiome.
Targeting TREM2 on tumor-associated macrophages enhances immunotherapy. Read more about Targeting TREM2 on tumor-associated macrophages enhances immunotherapy.
CCR2 deficiency alters activation of microglia subsets in traumatic brain injury. Read more about CCR2 deficiency alters activation of microglia subsets in traumatic brain injury.
Brown adipocyte ATF4 activation improves thermoregulation and systemic metabolism. Read more about Brown adipocyte ATF4 activation improves thermoregulation and systemic metabolism.
Topoisomerase I inhibition and peripheral nerve injury induce DNA breaks and ATF3-associated axon regeneration in sensory neurons. Read more about Topoisomerase I inhibition and peripheral nerve injury induce DNA breaks and ATF3-associated axon regeneration in sensory neurons.
Selective deletion of human leukocyte antigens protects stem cell-derived islets from immune rejection. Read more about Selective deletion of human leukocyte antigens protects stem cell-derived islets from immune rejection.
