A farnesyltransferase inhibitor improves disease phenotypes in mice with a Hutchinson-Gilford progeria syndrome mutation. Read more about A farnesyltransferase inhibitor improves disease phenotypes in mice with a Hutchinson-Gilford progeria syndrome mutation.
Inhibition of T cell activation and autoimmune diabetes using a B cell surface-linked CTLA-4 agonist. Read more about Inhibition of T cell activation and autoimmune diabetes using a B cell surface-linked CTLA-4 agonist.
The A2B adenosine receptor protects against inflammation and excessive vascular adhesion. Read more about The A2B adenosine receptor protects against inflammation and excessive vascular adhesion.
Ligation of protease-activated receptor 1 enhances alpha(v)beta6 integrin-dependent TGF-beta activation and promotes acute lung injury. Read more about Ligation of protease-activated receptor 1 enhances alpha(v)beta6 integrin-dependent TGF-beta activation and promotes acute lung injury.
Neutrophils and their Fc gamma receptors are essential in a mouse model of transfusion-related acute lung injury. Read more about Neutrophils and their Fc gamma receptors are essential in a mouse model of transfusion-related acute lung injury.
Anti-CD3 and nasal proinsulin combination therapy enhances remission from recent-onset autoimmune diabetes by inducing Tregs. Read more about Anti-CD3 and nasal proinsulin combination therapy enhances remission from recent-onset autoimmune diabetes by inducing Tregs.
Harnessing preclinical mouse models to inform human clinical cancer trials. Read more about Harnessing preclinical mouse models to inform human clinical cancer trials.
Differential exoprotease activities confer tumor-specific serum peptidome patterns. Read more about Differential exoprotease activities confer tumor-specific serum peptidome patterns.
Integration of flow-dependent endothelial phenotypes by Kruppel-like factor 2. Read more about Integration of flow-dependent endothelial phenotypes by Kruppel-like factor 2.
TCR stimulation with modified anti-CD3 mAb expands CD8+ T cell population and induces CD8+CD25+ Tregs. Read more about TCR stimulation with modified anti-CD3 mAb expands CD8+ T cell population and induces CD8+CD25+ Tregs.
