Unbiased modifier screen reveals that signal strength determines the regulatory role murine TLR9 plays in autoantibody production. Read more about Unbiased modifier screen reveals that signal strength determines the regulatory role murine TLR9 plays in autoantibody production.
A novel model for IFN-γ-mediated autoinflammatory syndromes. Read more about A novel model for IFN-γ-mediated autoinflammatory syndromes.
Antigen recognition in the islets changes with progression of autoimmune islet infiltration. Read more about Antigen recognition in the islets changes with progression of autoimmune islet infiltration.
Restriction of IL-22-producing T cell responses and differential regulation of regulatory T cell compartments by zinc finger transcription factor Ikaros. Read more about Restriction of IL-22-producing T cell responses and differential regulation of regulatory T cell compartments by zinc finger transcription factor Ikaros.
Cutting edge: the UNC93B1 tyrosine-based motif regulates trafficking and TLR responses via separate mechanisms. Read more about Cutting edge: the UNC93B1 tyrosine-based motif regulates trafficking and TLR responses via separate mechanisms.
Zap70 is essential for long-term survival of naive CD8 T cells. Read more about Zap70 is essential for long-term survival of naive CD8 T cells.
Cutting edge: An antibody recognizing ancestral endogenous virus glycoproteins mediates antibody-dependent cellular cytotoxicity on HIV-1-infected cells. Read more about Cutting edge: An antibody recognizing ancestral endogenous virus glycoproteins mediates antibody-dependent cellular cytotoxicity on HIV-1-infected cells.
Human NKG2E is expressed and forms an intracytoplasmic complex with CD94 and DAP12. Read more about Human NKG2E is expressed and forms an intracytoplasmic complex with CD94 and DAP12.
Immune memory-boosting dose of rapamycin impairs macrophage vesicle acidification and curtails glycolysis in effector CD8 cells, impairing defense against acute infections. Read more about Immune memory-boosting dose of rapamycin impairs macrophage vesicle acidification and curtails glycolysis in effector CD8 cells, impairing defense against acute infections.
