A combined proteomics/genomics approach links hepatitis C virus infection with nonsense-mediated mRNA decay. Read more about A combined proteomics/genomics approach links hepatitis C virus infection with nonsense-mediated mRNA decay.
Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes. Read more about Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.
Innate antiviral host defense attenuates TGF-β function through IRF3-mediated suppression of Smad signaling. Read more about Innate antiviral host defense attenuates TGF-β function through IRF3-mediated suppression of Smad signaling.
Quantitative proteomics reveal a feedforward mechanism for mitochondrial PARKIN translocation and ubiquitin chain synthesis. Read more about Quantitative proteomics reveal a feedforward mechanism for mitochondrial PARKIN translocation and ubiquitin chain synthesis.
Structural asymmetry in the closed state of mitochondrial Hsp90 (TRAP1) supports a two-step ATP hydrolysis mechanism. Read more about Structural asymmetry in the closed state of mitochondrial Hsp90 (TRAP1) supports a two-step ATP hydrolysis mechanism.
Ubiquitin ligase trapping identifies an SCF(Saf1) pathway targeting unprocessed vacuolar/lysosomal proteins. Read more about Ubiquitin ligase trapping identifies an SCF(Saf1) pathway targeting unprocessed vacuolar/lysosomal proteins.
An MRAS, SHOC2, and SCRIB complex coordinates ERK pathway activation with polarity and tumorigenic growth. Read more about An MRAS, SHOC2, and SCRIB complex coordinates ERK pathway activation with polarity and tumorigenic growth.
The translational landscape of the mammalian cell cycle. Read more about The translational landscape of the mammalian cell cycle.
A lipid E-MAP identifies Ubx2 as a critical regulator of lipid saturation and lipid bilayer stress. Read more about A lipid E-MAP identifies Ubx2 as a critical regulator of lipid saturation and lipid bilayer stress.
Division of labor between the chromodomains of HP1 and Suv39 methylase enables coordination of heterochromatin spread. Read more about Division of labor between the chromodomains of HP1 and Suv39 methylase enables coordination of heterochromatin spread.
