Transcription and DNA replication collisions lead to large tandem duplications and expose targetable therapeutic vulnerabilities in cancer. Read more about Transcription and DNA replication collisions lead to large tandem duplications and expose targetable therapeutic vulnerabilities in cancer.
Targeting therapy-persistent residual disease. Read more about Targeting therapy-persistent residual disease.
Tumor-associated macrophages restrict CD8+ T cell function through collagen deposition and metabolic reprogramming of the breast cancer microenvironment. Read more about Tumor-associated macrophages restrict CD8+ T cell function through collagen deposition and metabolic reprogramming of the breast cancer microenvironment.
Targeting a lineage-specific PI3Kɣ-Akt signaling module in acute myeloid leukemia using a heterobifunctional degrader molecule. Read more about Targeting a lineage-specific PI3Kɣ-Akt signaling module in acute myeloid leukemia using a heterobifunctional degrader molecule.
PERCEPTION predicts patient response and resistance to treatment using single-cell transcriptomics of their tumors. Read more about PERCEPTION predicts patient response and resistance to treatment using single-cell transcriptomics of their tumors.
KRAS degradation averts PDAC chemoresistance. Read more about KRAS degradation averts PDAC chemoresistance.
Structural surfaceomics reveals an AML-specific conformation of integrin β2 as a CAR T cellular therapy target. Read more about Structural surfaceomics reveals an AML-specific conformation of integrin β2 as a CAR T cellular therapy target.
Understanding inequities in precision oncology diagnostics. Read more about Understanding inequities in precision oncology diagnostics.
