Overcoming resistance to HER2 inhibitors through state-specific kinase binding. Read more about Overcoming resistance to HER2 inhibitors through state-specific kinase binding.
Photoswitchable diacylglycerols enable optical control of protein kinase C. Read more about Photoswitchable diacylglycerols enable optical control of protein kinase C.
A reactivity-based probe of the intracellular labile ferrous iron pool. Read more about A reactivity-based probe of the intracellular labile ferrous iron pool.
Essential biphasic role for JAK3 catalytic activity in IL-2 receptor signaling. Read more about Essential biphasic role for JAK3 catalytic activity in IL-2 receptor signaling.
Parallel shRNA and CRISPR-Cas9 screens enable antiviral drug target identification. Read more about Parallel shRNA and CRISPR-Cas9 screens enable antiviral drug target identification.
Prolonged and tunable residence time using reversible covalent kinase inhibitors. Read more about Prolonged and tunable residence time using reversible covalent kinase inhibitors.
GSK-3 modulates cellular responses to a broad spectrum of kinase inhibitors. Read more about GSK-3 modulates cellular responses to a broad spectrum of kinase inhibitors.
Covalent docking of large libraries for the discovery of chemical probes. Read more about Covalent docking of large libraries for the discovery of chemical probes.
Unraveling the mechanism of cell death induced by chemical fibrils. Read more about Unraveling the mechanism of cell death induced by chemical fibrils.
Activation of Hsp70 reduces neurotoxicity by promoting polyglutamine protein degradation. Read more about Activation of Hsp70 reduces neurotoxicity by promoting polyglutamine protein degradation.
