Loss of MCU prevents mitochondrial fusion in G1-S phase and blocks cell cycle progression and proliferation. Read more about Loss of MCU prevents mitochondrial fusion in G1-S phase and blocks cell cycle progression and proliferation.
Specificity, versatility, and control of TGF-β family signaling. Read more about Specificity, versatility, and control of TGF-β family signaling.
Chronic TGF-β exposure drives stabilized EMT, tumor stemness, and cancer drug resistance with vulnerability to bitopic mTOR inhibition. Read more about Chronic TGF-β exposure drives stabilized EMT, tumor stemness, and cancer drug resistance with vulnerability to bitopic mTOR inhibition.
Inactivating mutations in Drosha mediate vascular abnormalities similar to hereditary hemorrhagic telangiectasia. Read more about Inactivating mutations in Drosha mediate vascular abnormalities similar to hereditary hemorrhagic telangiectasia.
IL-2Rβ abundance differentially tunes IL-2 signaling dynamics in CD4+ and CD8+ T cells. Read more about IL-2Rβ abundance differentially tunes IL-2 signaling dynamics in CD4+ and CD8+ T cells.
Evaluation of the selectivity and sensitivity of isoform- and mutation-specific RAS antibodies. Read more about Evaluation of the selectivity and sensitivity of isoform- and mutation-specific RAS antibodies.
Cancer-associated arginine-to-histidine mutations confer a gain in pH sensing to mutant proteins. Read more about Cancer-associated arginine-to-histidine mutations confer a gain in pH sensing to mutant proteins.
In silico modeling identifies CD45 as a regulator of IL-2 synergy in the NKG2D-mediated activation of immature human NK cells. Read more about In silico modeling identifies CD45 as a regulator of IL-2 synergy in the NKG2D-mediated activation of immature human NK cells.
Hyperactive locomotion in a Drosophila model is a functional readout for the synaptic abnormalities underlying fragile X syndrome. Read more about Hyperactive locomotion in a Drosophila model is a functional readout for the synaptic abnormalities underlying fragile X syndrome.
Chemoattractant concentration-dependent tuning of ERK signaling dynamics in migrating neutrophils. Read more about Chemoattractant concentration-dependent tuning of ERK signaling dynamics in migrating neutrophils.
