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For many common childhood cancers, radiation therapy can be an effective, even curative, treatment. However, long-term survivors are at risk for developing new, or secondary, cancers as a consequence of radiation, sometimes decades later. Children with cancers like medulloblastoma and

Human papillomavirus (HPV) is widely known to cause nearly all cases of cervical cancer. However, you might not know that HPV also causes 70 percent of oropharyngeal cancer, a subset of head and neck cancers that affect the mouth, tongue, and tonsils. Although vaccines that protect against HPV

Glioblastoma characterized by "palisading necrosis" (red). Credit: Costello Lab/UCSF. UC San Francisco researchers have discovered how a mutation in a gene regulator called the TERTpromoter — the third most common mutation among all human cancers and the most common mutation in the deadly brain

Genetic mutations in a form of non–small cell lung cancer (NSCLC) may drive tumor formation by blurring cells’ perception of key growth signals, according to a new laboratory study published Aug. 31, 2018, in Science. The research, led by UC San Francisco researchers, could have important

UCSF Benioff Children’s Hospitals are harnessing next-generation genomic technology to develop individualized drug cocktails in a new trial for children with a type of malignant brain tumor. This precision-medicine approach offers a new strategy in the treatment for high-grade glioma, an intractable

Each year, nearly 16,000 U.S. children and teens are diagnosed with cancer. But only 4 percent of federal cancer research funding is earmarked to develop new treatments and cures for children battling this heartbreaking disease – an amount that is far below what is actually needed. Just as pink has

In a study appearing Aug. 29, 2018, in JAMA Surgery, UCSF researchers found that 58 percent of women who resided in a nursing home for more than 90 days before breast cancer surgery experienced significant functional decline one year after surgery. The study found that women with functional