The American Association for Cancer Research (AACR) today released its Cancer Disparities Progress Report 2022. The publication raises awareness of the enormous toll that cancer exacts on racial and ethnic minorities and other medically underserved populations, while highlighting areas of recent progress in reducing cancer health disparities. The report also provides specific recommendations for achieving health equity, which is a basic human right for all people regardless of their race, ethnicity, sexual orientation, gender identity, socioeconomic status, or community in which they live. It is the second AACR report on this topic.