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  • Weak base pairing in both seed and 3' regions reduces RNAi off-targets and enhances si/shRNA designs.

Weak base pairing in both seed and 3' regions reduces RNAi off-targets and enhances si/shRNA designs.

Author List
Gu S, Zhang Y, Jin L, Huang Y, Zhang F, Bassik MC, Kampmann M, Kay MA
Publication
Nucleic acids research
Publication ID (Profile URL)
https://researcherprofiles.org/profile/1184092
Publication Year
2014
PubMed ID
25270879
Publication Title
Gu S, Zhang Y, Jin L, Huang Y, Zhang F, Bassik MC, Kampmann M, Kay MA. Weak base pairing in both seed and 3' regions reduces RNAi off-targets and enhances si/shRNA designs. Nucleic Acids Res. 2014 Oct 29; 42(19):12169-76.