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The primary mechanism of cytotoxicity of the chemotherapeutic agent CX-5461 is topoisomerase II poisoning.

Author List
Bruno PM, Lu M, Dennis KA, Inam H, Moore CJ, Sheehe J, Elledge SJ, Hemann MT, Pritchard JR
Publication
Proceedings of the National Academy of Sciences of the United States of America
Publication ID (Profile URL)
https://researcherprofiles.org/profile/392961535
Publication Year
2020
PubMed ID
32041867
Publication Title
Bruno PM, Lu M, Dennis KA, Inam H, Moore CJ, Sheehe J, Elledge SJ, Hemann MT, Pritchard JR. The primary mechanism of cytotoxicity of the chemotherapeutic agent CX-5461 is topoisomerase II poisoning. Proc Natl Acad Sci U S A. 2020 02 25; 117(8):4053-4060.