IL-13 and IL-17A activate β1 integrin through an NF-kB/Rho kinase/PIP5K1γ pathway to enhance force transmission in airway smooth muscle. Read more about IL-13 and IL-17A activate β1 integrin through an NF-kB/Rho kinase/PIP5K1γ pathway to enhance force transmission in airway smooth muscle.
Long noncoding RNA LIRIL2R modulates FOXP3 levels and suppressive function of human CD4+ regulatory T cells by regulating IL2RA. Read more about Long noncoding RNA LIRIL2R modulates FOXP3 levels and suppressive function of human CD4+ regulatory T cells by regulating IL2RA.
Tau fibrils induce nanoscale membrane damage and nucleate cytosolic tau at lysosomes. Read more about Tau fibrils induce nanoscale membrane damage and nucleate cytosolic tau at lysosomes.
CRISPRi screens identify the lncRNA, LOUP, as a multifunctional locus regulating macrophage differentiation and inflammatory signaling. Read more about CRISPRi screens identify the lncRNA, LOUP, as a multifunctional locus regulating macrophage differentiation and inflammatory signaling.
Modeling homologous chromosome recognition via nonspecific interactions. Read more about Modeling homologous chromosome recognition via nonspecific interactions.
Aire mediates tolerance to insulin through thymic trimming of high-affinity T cell clones. Read more about Aire mediates tolerance to insulin through thymic trimming of high-affinity T cell clones.
A general approach for selection of epitope-directed binders to proteins. Read more about A general approach for selection of epitope-directed binders to proteins.
The clustered gamma protocadherin PcdhγC4 isoform regulates cortical interneuron programmed cell death in the mouse cortex. Read more about The clustered gamma protocadherin PcdhγC4 isoform regulates cortical interneuron programmed cell death in the mouse cortex.
ENPP1 is an innate immune checkpoint of the anticancer cGAMP-STING pathway in breast cancer. Read more about ENPP1 is an innate immune checkpoint of the anticancer cGAMP-STING pathway in breast cancer.
Loss of PPARγ activity characterizes early protumorigenic stromal reprogramming and dictates the therapeutic window of opportunity. Read more about Loss of PPARγ activity characterizes early protumorigenic stromal reprogramming and dictates the therapeutic window of opportunity.
