Macrophages release neuraminidase and cleaved calreticulin for programmed cell removal. Read more about Macrophages release neuraminidase and cleaved calreticulin for programmed cell removal.
Blocking C-terminal processing of KRAS4b via a direct covalent attack on the CaaX-box cysteine. Read more about Blocking C-terminal processing of KRAS4b via a direct covalent attack on the CaaX-box cysteine.
Structural basis of disease mutation and substrate recognition by the human SLC2A9 transporter. Read more about Structural basis of disease mutation and substrate recognition by the human SLC2A9 transporter.
Mechanism-guided engineering of a minimal biological particle for genome editing. Read more about Mechanism-guided engineering of a minimal biological particle for genome editing.
Subcellular activation of β-adrenergic receptors using a spatially restricted antagonist. Read more about Subcellular activation of β-adrenergic receptors using a spatially restricted antagonist.
IL-13 and IL-17A activate β1 integrin through an NF-kB/Rho kinase/PIP5K1γ pathway to enhance force transmission in airway smooth muscle. Read more about IL-13 and IL-17A activate β1 integrin through an NF-kB/Rho kinase/PIP5K1γ pathway to enhance force transmission in airway smooth muscle.
A tandem activity-based sensing and labeling strategy reveals antioxidant response element regulation of labile iron pools. Read more about A tandem activity-based sensing and labeling strategy reveals antioxidant response element regulation of labile iron pools.
Long noncoding RNA LIRIL2R modulates FOXP3 levels and suppressive function of human CD4+ regulatory T cells by regulating IL2RA. Read more about Long noncoding RNA LIRIL2R modulates FOXP3 levels and suppressive function of human CD4+ regulatory T cells by regulating IL2RA.
Tau fibrils induce nanoscale membrane damage and nucleate cytosolic tau at lysosomes. Read more about Tau fibrils induce nanoscale membrane damage and nucleate cytosolic tau at lysosomes.
CRISPRi screens identify the lncRNA, LOUP, as a multifunctional locus regulating macrophage differentiation and inflammatory signaling. Read more about CRISPRi screens identify the lncRNA, LOUP, as a multifunctional locus regulating macrophage differentiation and inflammatory signaling.
