Blocking C-terminal processing of KRAS4b via a direct covalent attack on the CaaX-box cysteine. Read more about Blocking C-terminal processing of KRAS4b via a direct covalent attack on the CaaX-box cysteine.
IL-13 and IL-17A activate β1 integrin through an NF-kB/Rho kinase/PIP5K1γ pathway to enhance force transmission in airway smooth muscle. Read more about IL-13 and IL-17A activate β1 integrin through an NF-kB/Rho kinase/PIP5K1γ pathway to enhance force transmission in airway smooth muscle.
A tandem activity-based sensing and labeling strategy reveals antioxidant response element regulation of labile iron pools. Read more about A tandem activity-based sensing and labeling strategy reveals antioxidant response element regulation of labile iron pools.
Long noncoding RNA LIRIL2R modulates FOXP3 levels and suppressive function of human CD4+ regulatory T cells by regulating IL2RA. Read more about Long noncoding RNA LIRIL2R modulates FOXP3 levels and suppressive function of human CD4+ regulatory T cells by regulating IL2RA.
Tau fibrils induce nanoscale membrane damage and nucleate cytosolic tau at lysosomes. Read more about Tau fibrils induce nanoscale membrane damage and nucleate cytosolic tau at lysosomes.
CRISPRi screens identify the lncRNA, LOUP, as a multifunctional locus regulating macrophage differentiation and inflammatory signaling. Read more about CRISPRi screens identify the lncRNA, LOUP, as a multifunctional locus regulating macrophage differentiation and inflammatory signaling.
Modeling homologous chromosome recognition via nonspecific interactions. Read more about Modeling homologous chromosome recognition via nonspecific interactions.
Aire mediates tolerance to insulin through thymic trimming of high-affinity T cell clones. Read more about Aire mediates tolerance to insulin through thymic trimming of high-affinity T cell clones.
A general approach for selection of epitope-directed binders to proteins. Read more about A general approach for selection of epitope-directed binders to proteins.
Vulnerability to APOBEC3G linked to the pathogenicity of deltaretroviruses. Read more about Vulnerability to APOBEC3G linked to the pathogenicity of deltaretroviruses.