Leucine aminopeptidase LyLAP enables lysosomal degradation of membrane proteins. | UCSF Helen Diller Family Comprehensive Cancer Center

Author List

Jain A, Heremans I, Rademaker G, Detomasi TC, Rohweder P, Anderson D, Zhang J, Hernandez GA, Gupta S, von Linde T, Lange M, Spacci M, Luo J, Citron YR, Olzmann JA, Dawson DW, Craik CS, Bommer G, Perera RM, Zoncu R

Publication

Science (New York, N.Y.)

Publication ID (Profile URL)

https://researcherprofiles.org/profile/613166817

Publication Year

2025

PubMed ID

40146846

Publication Title

Jain A, Heremans I, Rademaker G, Detomasi TC, Rohweder P, Anderson D, Zhang J, Hernandez GA, Gupta S, von Linde T, Lange M, Spacci M, Luo J, Citron YR, Olzmann JA, Dawson DW, Craik CS, Bommer G, Perera RM, Zoncu R. Leucine aminopeptidase LyLAP enables lysosomal degradation of membrane proteins. Science. 2025 Mar 28; 387(6741):eadq8331.