Derepressing nuclear pyruvate dehydrogenase induces therapeutic cancer cell reprogramming.

Zhao T, He L, Wong LP, Mei S, Xia J, Xu Y, Van Vranken JG, Mazzola M, Chen L, Rhee C, Fang T, Fukushima T, Sayles LC, Diaz M, Gibbons JAB, Mostoslavsky R, Gygi SP, Dou Z, Sykes DB, Sadreyev RI, Sweet-Cordero EA, Scadden DT