Research Funding

  • September 1, 2016 - June 30, 2026 - Clinical & Immunological Study of Treatment Withdrawal in E-Ag Negative Hepatitis B , Co-Principal Investigator . Sponsor: NIH, Sponsor Award ID: R01DK103735
  • August 16, 2018 - July 31, 2022 - Identifying and modulating therapeutic targets in a model of hepatitis B , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R01AI139762
  • August 24, 2012 - August 31, 2018 - Identifying and modulating therapeutic targets in a model of hepatitis B , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R56DK093646
  • August 24, 2012 - September 19, 2017 - Identifying and modulating therapeutic targets in a model of hepatitis B , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R01DK093646


Swarthmore College, Swarthmore, PA, 1984-85 Rice University, Houston, Texas, BA, 1986, Biology & Philosophy
Yale University, MD 1993, Medicine
Yale University, PhD, 1994, Immunobiology
Stanford University, Residency, 1993-95 Internal Medicine
University of California, San Francisco, Clinical Fellow, 1995-96, Infectious Diseases
University of California, San Francisco, Fellowship, 1996-2000, Microbiol & Immunology

Honors & Awards

  • 1982
    Westinghouse Science Talent Search honors group
  • 1992
    NIH Resident research award
  • 1986-1992
    NIH Fellowship -Medical Scientist Training Program Yale University
  • 1992
    Molecular Medicine Fellowship, University of California at San Francisco
  • 1997-2002
    Howard Hughes Postdoctoral Research Fellowship for Physicians
  • 1992
    UCSF Liver center pilot research grant
  • 2000-2002
    Pfizer Postdoctoral Fellowship in Infectious Diseases
  • 2003-2002
    Burroughs Wellcome Career Award in the Biomedical Sciences
  • 2002
    HHMI/BWF Leadership Coaching Award
  • 2002
    American Gastroenterological Association Fiterman Basic Science Award
  • 2004-2002
    American Liver Foundation Liver Scholar Award
  • 2005-2002
    Cancer Research Institute Investigator award
  • 2006-2011
    Burroughs Wellcome Fund Investigator in Pathogenesis of Infectious Disease
  • 2011-2013
    UCSF Program in Breakthrough Biomedical Research Award

Selected Publications

  1. Patel RK, Jaszczak RG, Im K, Carey ND, Courau T, Bunis DG, Samad B, Avanesyan L, Chew NW, Stenske S, Jespersen JM, Publicover J, Edwards AW, Naser M, Rao AA, Lupin-Jimenez L, Krummel MF, Cooper S, Baron JL, Combes AJ, Fragiadakis GK. Cyclone: an accessible pipeline to analyze, evaluate, and optimize multiparametric cytometry data. Front Immunol. 2023; 14:1167241.  View on PubMed
  2. Natarajan V, Simoneau CR, Erickson AL, Meyers NL, Baron JL, Cooper S, McDevitt TC, Ott M. Modelling T-cell immunity against hepatitis C virus with liver organoids in a microfluidic coculture system. Open Biol. 2022 03; 12(3):210320.  View on PubMed
  3. Seed RI, Kobayashi K, Ito S, Takasaka N, Cormier A, Jespersen JM, Publicover J, Trilok S, Combes AJ, Chew NW, Chapman J, Krummel MF, Lou J, Marks J, Cheng Y, Baron JL, Nishimura SL. A tumor-specific mechanism of Treg enrichment mediated by the integrin αvβ8. Sci Immunol. 2021 03 26; 6(57).  View on PubMed
  4. Campbell MG, Cormier A, Ito S, Seed RI, Bondesson AJ, Lou J, Marks JD, Baron JL, Cheng Y, Nishimura SL. Cryo-EM Reveals Integrin-Mediated TGF-β Activation without Release from Latent TGF-β. Cell. 2020 02 06; 180(3):490-501.e16.  View on PubMed
  5. Melody G. Campbell, Anthony Cormier, Saburo Ito, Shenping Wu, Jianlong Lou, James Marks, Jody L. Baron, Stephen L. Nishimura, Yifan Cheng. Structural Studies avß8 Integrin by Single Particle Cryo-EM. Microscopy and Microanalysis. 2019 Aug 1; 25(S2):1312-1313.  View on PubMed
  6. Takasaka N, Seed RI, Cormier A, Bondesson AJ, Lou J, Elattma A, Ito S, Yanagisawa H, Hashimoto M, Ma R, Levine MD, Publicover J, Potts R, Jespersen JM, Campbell MG, Conrad F, Marks JD, Cheng Y, Baron JL, Nishimura SL. Integrin αvβ8-expressing tumor cells evade host immunity by regulating TGF-β activation in immune cells. JCI Insight. 2018 10 18; 3(20).  View on PubMed
  7. Cormier A, Campbell MG, Ito S, Wu S, Lou J, Marks J, Baron JL, Nishimura SL, Cheng Y. Cryo-EM structure of the αvβ8 integrin reveals a mechanism for stabilizing integrin extension. Nat Struct Mol Biol. 2018 08; 25(8):698-704.  View on PubMed
  8. Publicover J, Gaggar A, Jespersen JM, Halac U, Johnson AJ, Goodsell A, Avanesyan L, Nishimura SL, Holdorf M, Mansfield KG, Judge JB, Koshti A, Croft M, Wakil AE, Rosenthal P, Pai E, Cooper S, Baron JL. An OX40/OX40L interaction directs successful immunity to hepatitis B virus. Sci Transl Med. 2018 03 21; 10(433).  View on PubMed
  9. Pierce AA, Duwaerts CC, Siao K, Mattis AN, Goodsell A, Baron JL, Maher JJ. CD18 deficiency improves liver injury in the MCD model of steatohepatitis. PLoS One. 2017; 12(9):e0183912.  View on PubMed
  10. Duwaerts CC, Amin AM, Siao K, Her C, Fitch M, Beysen C, Turner SM, Goodsell A, Baron JL, Grenert JP, Cho SJ, Maher JJ. Specific Macronutrients Exert Unique Influences on the Adipose-Liver Axis to Promote Hepatic Steatosis in Mice. Cell Mol Gastroenterol Hepatol. 2017 Sep; 4(2):223-236.  View on PubMed
  11. Yanagisawa H, Hashimoto M, Minagawa S, Takasaka N, Ma R, Moermans C, Ito S, Araya J, Budelsky A, Goodsell A, Baron JL, Nishimura SL. Role of IL-17A in murine models of COPD airway disease. Am J Physiol Lung Cell Mol Physiol. 2017 01 01; 312(1):L122-L130.  View on PubMed
  12. Publicover J, Jespersen JM, Johnson AJ, Nishimura SL, Goodsell A, Wakil AE, Rosenthal P, Pai E, Avanesyan L, Cooper S, Baron JL. Liver capsule: Age-influenced hepatic immune priming determines HBV infection fate: Implications from mouse to man. Hepatology. 2016 Jan; 63(1):260.  View on PubMed
  13. Hashimoto M, Yanagisawa H, Minagawa S, Sen D, Ma R, Murray LA, Tsui P, Lou J, Marks JD, Baron JL, Krummel MF, Nishimura SL. TGF-β-Dependent Dendritic Cell Chemokinesis in Murine Models of Airway Disease. J Immunol. 2015 Aug 01; 195(3):1182-90.  View on PubMed
  14. Brand OJ, Somanath S, Moermans C, Yanagisawa H, Hashimoto M, Cambier S, Markovics J, Bondesson AJ, Hill A, Jablons D, Wolters P, Lou J, Marks JD, Baron JL, Nishimura SL. Transforming Growth Factor-β and Interleukin-1β Signaling Pathways Converge on the Chemokine CCL20 Promoter. J Biol Chem. 2015 Jun 05; 290(23):14717-28.  View on PubMed
  15. Hashimoto M, Yanagisawa H, Minagawa S, Sen D, Goodsell A, Ma R, Moermans C, McKnelly KJ, Baron JL, Krummel MF, Nishimura SL. A critical role for dendritic cells in the evolution of IL-1β-mediated murine airway disease. J Immunol. 2015 Apr 15; 194(8):3962-9.  View on PubMed
  16. Minagawa S, Lou J, Seed RI, Cormier A, Wu S, Cheng Y, Murray L, Tsui P, Connor J, Herbst R, Govaerts C, Barker T, Cambier S, Yanagisawa H, Goodsell A, Hashimoto M, Brand OJ, Cheng R, Ma R, McKnelly KJ, Wen W, Hill A, Jablons D, Wolters P, Kitamura H, Araya J, Barczak AJ, Erle DJ, Reichardt LF, Marks JD, Baron JL, Nishimura SL. Selective targeting of TGF-β activation to treat fibroinflammatory airway disease. Sci Transl Med. 2014 Jun 18; 6(241):241ra79.  View on PubMed
  17. Fomin ME, Zhou Y, Beyer AI, Publicover J, Baron JL, Muench MO. Production of factor VIII by human liver sinusoidal endothelial cells transplanted in immunodeficient uPA mice. PLoS One. 2013; 8(10):e77255.  View on PubMed
  18. Jean Publicover, Anuj Gaggar, Stephen Nishimura, Christine M. Van Horn, Amanda Goodsell, Marcus O. Muench, R. Lee Reinhardt, Nico van Rooijen, Adil E. Wakil Marion Peters, Jason G. Cyster, David J. Erle, Philip Rosenthal, Lia Avanesyan, Rosanne Spolski, Warren J. Leonard, Stewart Cooper, Jody L. Baron. S-3 Age-dependent hepatic lymphoid organization directs immune priming, cytokine production, and successful immunity to Hepatitis B virus. Cytokine. 2013 Sep 1; 63(3):241.  View on PubMed
  19. Publicover J, Gaggar A, Nishimura S, Van Horn CM, Goodsell A, Muench MO, Reinhardt RL, van Rooijen N, Wakil AE, Peters M, Cyster JG, Erle DJ, Rosenthal P, Cooper S, Baron JL. Age-dependent hepatic lymphoid organization directs successful immunity to hepatitis B. J Clin Invest. 2013 Sep; 123(9):3728-39.  View on PubMed
  20. Zeissig S, Murata K, Sweet L, Publicover J, Hu Z, Kaser A, Bosse E, Iqbal J, Hussain MM, Balschun K, Röcken C, Arlt A, Günther R, Hampe J, Schreiber S, Baron JL, Moody DB, Liang TJ, Blumberg RS. Hepatitis B virus-induced lipid alterations contribute to natural killer T cell-dependent protective immunity. Nat Med. 2012 Jul; 18(7):1060-8.  View on PubMed

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