Research Summary

Dr. Hala Borno is faculty at UCSF and an Assistant Professor in the Department of Medicine and Division of Hematology/Oncology and co-Medical Director of the Genitourinary Medical Oncology Clinic at the Helen Diller Family Comprehensive Cancer Center (HDFCCC) at the University of California San Francisco (UCSF). Dr. Borno is a medical oncologist with clinical expertise in the management of advanced urologic malignancies such as prostate, kidney, bladder, and testicular cancers. At HDFCCC, Dr. Borno serves on the executive leadership committee for the Prostate Cancer Program and the Liaison to the Office of Community Engagement. She is also a member of the American Society of Clinical Oncology Social Determinants of Health working group, and GU committee for NRG oncology. She serves as the Vice Chair of the Health Disparities Committee for Alliance for Clinical Trials in Oncology.

Dr. Borno's research program consists of prostate cancer therapeutic development and cancer disparities. She serves as medical oncology co-chair for phase III clinical trials and is the principal investigator for clinical trials conducted at HDFCCC in advanced prostate cancer. Dr. Borno has an extensive research program on the promotion of equity in cancer precision medicine.

She has developed novel recruitment technologies that are clinician and patient facing to promote diversity and inclusion of racial/ethnic minorities in clinical trials. Dr. Borno used human-centered design to develop Trial LibraryTM, a patient facing clinical trial matching tool. Dr. Borno's research has been featured in peer-reviewed journals such JAMA Oncology, Cancer, and Nature. Her work has been covered by national news outlets such as NPR, Washington Post, CBS News, Bloomberg News, and STAT News.

Dr. Borno graduated with honors in biochemistry and received her medical degree from the University of North Carolina at Chapel Hill where she was a Medical Alumni Loyalty Fund Scholar. She completed her internal medicine residency and medical oncology fellowship training at UCSF. She served as chief oncology fellow at UCSF and was a National Institute on Aging T32 research fellow in the Division of Geriatrics.

Education

University of North Carolina at Chapel Hill, B.S., 05/2008, Biochemistry
University of North Carolina at Chapel Hill, M.D., 05/2013, Medicine
University of California, San Francisco, Intern, 06/2014, Internal Medicine
University of California, San Francisco, Resident, 06/2016, Internal Medicine

Honors & Awards

  • 2009
    Foreign Language Area Studies Fellowship
  • 2011-2012
    Furlow Fund Global Health Research Fellowship, University of North Carolina at Chapel Hill
  • 2009-2013
    Medical Alumni Loyalty Fund Scholarship
  • 2013
    Arnold P. Gold Foundation
  • 2013
    Daniel T. Young Peace and Social Justice Award
  • 2017-present
    Geriatrics T32 NIH Grant
  • 2017-present
    Inside Out Accelerator Grant from the Clinical Innovation Center

Selected Publications

  1. Hala T. Borno, Tracy Kuo Lin, Sylvia Zhang, Andrea Skafel, Alyssa Lalanne, Dana Dornsife, Robert Johnson, Darcy Spicer, Eric J. Small, Kim F. Rhoads. Accelerating cancer clinical trial recruitment through a financial reimbursement program integrated with patient navigation: an interrupted time series analysis. Journal of Cancer Policy. 2021 Dec 1; 30:100305.  View on PubMed
  2. Abel MK, Melisko ME, Rugo HS, Chien AJ, Diaz I, Levine JK, Griffin A, McGuire J, Esserman LJ, Borno HT, Mukhtar RA. Decreased enrollment in breast cancer trials by histologic subtype: does invasive lobular carcinoma resist RECIST? NPJ Breast Cancer. 2021 Oct 25; 7(1):139.  View on PubMed
  3. Natsuhara KH, Borno HT. The Distance Between Us: the COVID-19 Pandemic's Effects on Burnout Among Resident Physicians. Med Sci Educ. 2021 Oct 15; 1-5.  View on PubMed
  4. Kenfield SA, Van Blarigan EL, Panchal N, Bang A, Zhang L, Graff RE, Chen YH, Ryan CJ, Luke A, Newton RU, Tenggara I, Schultz B, Wang E, Lavaki E, Zuniga K, Pinto N, Borno H, Aggarwal R, Friedlander T, Koshkin VS, Harzstark A, Small E, Chan JM. Feasibility, safety, and acceptability of a remotely monitored exercise pilot CHAMP: A Clinical trial of High-intensity Aerobic and resistance exercise for Metastatic castrate-resistant Prostate cancer. Cancer Med. 2021 Oct 12.  View on PubMed
  5. Meera Vimala Ragavan, Alyssa LaLanne, Andrea Skafel, Julian C. Hong, Anobel Y. Odisho, Sasha Yousefi, Eric Jay Small, Hala Borno. Evaluating changes in “good safety monitoring” for cancer clinical trial participants during the COVID-19 pandemic. Journal of Clinical Oncology. 2021 Oct 1; 39(28_suppl):217-217.  View on PubMed
  6. Meera Vimala Ragavan, Rosie Cunningham, Andrea Incudine, Hala Borno, Thomas Stivers. Predictors of high financial distress in a national, multiethnic sample of patients with cancer. Journal of Clinical Oncology. 2021 Oct 1; 39(28_suppl):149-149.  View on PubMed
  7. J. Hong, H.T. Borno, O. Harismendy, S. Yousefi, P. Cinar, H.S. Rugo, M-O. Kim, V.S. Koshkin, A. Bailey, R.R. McKay, E.J. Small. 1571P COVID-19 positivity rates in patients with an active cancer diagnosis in the University of California Cancer Consortium. Annals of Oncology. 2021 Sep 21; 32:s1135.  View on PubMed
  8. Hala T. Borno, Sylvia Zhang, Elena Nieves, Dana Dornsife, Robert Johnson, Darcy Spicer, Tracy K. Lin. Broad inclusion leads to maximal value – examining travel costs associated with clinical trial participation. . 2021 Aug 26.  View on PubMed
  9. Hala T. Borno, Nichole Legaspi, Sam Brondfield, Errol Philip, Pelin Cinar, Li Zhang. Implementation of a medical oncology fellow-initiated financial toxicity screening program in outpatient medical oncology clinics. . 2021 Aug 25.  View on PubMed
  10. Palmer NR, Borno HT, Gregorich SE, Livaudais-Toman J, Kaplan CP. Prostate cancer patients' self-reported participation in research: an examination of racial/ethnic disparities. Cancer Causes Control. 2021 Oct; 32(10):1161-1172.  View on PubMed
  11. Mary Kathryn Abel, Michelle E. Melisko, Hope S. Rugo, Amy Jo Chien, Italia Diaz, Julia K. Levine, Ann Griffin, Joseph McGuire, Laura Esserman, Hala Borno, Rita A. Mukhtar. Decreased enrollment of patients with advanced lobular breast cancer compared to ductal breast cancer in interventional clinical trials. Journal of Clinical Oncology. 2021 May 20; 39(15_suppl):1092-1092.  View on PubMed
  12. Rahul Raj Aggarwal, Srey Luch Sam, Vadim S Koshkin, Eric Jay Small, Felix Y Feng, Ivan de Kouchkovsky, Daniel H Kwon, Terence W. Friedlander, Hala Borno, Rohit Bose, Jonathan Chou, Arpita Desai, Tammy J. Rodvelt, Maya Aslam, Medini Rastogi, Lawrence Fong, Thomas A Hope. Immunogenic priming with 177 Lu-PSMA-617 plus pembrolizumab in metastatic castration resistant prostate cancer (mCRPC): A phase 1b study. Journal of Clinical Oncology. 2021 May 20; 39(15_suppl):5053-5053.  View on PubMed
  13. Michael Glover, Julie Wu, Daniel H Kwon, Sylvia Zhang, Solomon Henry, Douglas Wood, Daniel Rubin, Hala Borno, Eric Jay Small, Lidia Schapira, Vadim S Koshkin, Sumit Shah. Patterns in cancer management changes for patients with COVID-19 in northern California. Journal of Clinical Oncology. 2021 May 20; 39(15_suppl):1535-1535.  View on PubMed
  14. Daniel H Kwon, Alan Paciorek, Li Zhang, Hala Borno, Arpita Desai, Rohit Bose, Jonathan Chou, Lawrence Fong, Terence W. Friedlander, Franklin W. Huang, Vadim S Koshkin, Eric Jay Small, Rahul Raj Aggarwal. Rate of skeletal-related events (SREs) for abiraterone acetate (AA) versus enzalutamide (ENZ) in prostate cancer: A population-based study using the SEER-Medicare database. Journal of Clinical Oncology. 2021 May 20; 39(15_suppl):e17038-e17038.  View on PubMed
  15. Divya V Natesan, Li Zhang, David Yoonsuk Oh, Sima P. Porten, Maxwell Meng, Raj Pruthi, Matthew R. Cooperberg, Peter Carroll, Jonathan Chou, Hala Borno, Rohit Bose, Arpita Desai, Daniel H Kwon, Anthony C. Wong, Felix Y Feng, Rahul Raj Aggarwal, Eric Jay Small, Lawrence Fong, Terence W. Friedlander, Vadim S Koshkin. Updated results of phase II trial using escalating doses of neoadjuvant atezolizumab for cisplatin-ineligible patients with nonmetastatic urothelial cancer (NCT02451423). Journal of Clinical Oncology. 2021 May 20; 39(15_suppl):e16510-e16510.  View on PubMed
  16. Borno HT, Andemeskel G, Palmer NR. Redefining Attribution From Patient to Health System-How the Notion of "Mistrust" Places Blame on Black Patients. JAMA Oncol. 2021 May 01; 7(5):780.  View on PubMed
  17. Miaskowski C, Paul SM, Snowberg K, Abbott M, Borno HT, Chang SM, Chen LM, Cohen B, Cooper BA, Hammer MJ, Kenfield SA, Kober KM, Laffan A, Levine JD, Pozzar R, Rhoads K, Tsai KK, Van Blarigan EL, Van Loon K. Loneliness and symptom burden in oncology patients during the COVID-19 pandemic. Cancer. 2021 09 01; 127(17):3246-3253.  View on PubMed
  18. Kelsey H Natsuhara, Li Zhang, Christopher A Carlos, Hala T Borno. Evaluating predictors of renal injury with sorafenib in hepatocellular carcinoma: A multi-ethnic cohort study. Journal of Onco-Nephrology. 2021 Apr 19; 239936932110092.  View on PubMed
  19. Kwon DH, Chou J, Yip SM, Reimers MA, Zhang L, Wright F, Dhawan MS, Borno HT, Desai A, Aggarwal RR, Wyatt AW, Small EJ, Alva AS, Chi KN, Feng FY, Koshkin VS. Differential treatment outcomes in BRCA1/2-, CDK12-, and ATM-mutated metastatic castration-resistant prostate cancer. Cancer. 2021 Jun 15; 127(12):1965-1973.  View on PubMed
  20. Stacy Loeb, Rada Mihalcea, Veronica Perez-Rosas, Alex Xu, Jacob Taylor, Nataliya Byrne, Dawn Walter, Marina Ness, Rebecca Robbins, Sylvia Zhang, Trevor Killeen, Divya Natesan, Hala T. Borno. Leveraging Social Media as a Thermometer to Gauge Patient and Caregiver Concerns: COVID-19 and Prostate Cancer. European Urology Open Science. 2021 Mar 1; 25:1-4.  View on PubMed

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