Research Summary

Dr. Braunstein is a radiation oncologist with a clinical interest in the treatment of pediatric, central nervous system, and soft tissue malignancies. He has expertise in modern radiation therapy techniques including stereotactic radiotherapy (Gamma Knife, Cyberknife, Linac-based SBRT), intraoperative radiotherapy, and intensity modulated radiation therapy.

Dr. Braunstein earned his M.D. at New York University School of Medicine where he also obtained a Ph.D. studying molecular pathways by which cancer cells mediate response to radiation. He currently serves as Vice Chair and Clinical Director of Radiation Oncology. His research focus includes mitigation of early and late toxicity in treatment of pediatric malignancies as well as optimizing combination of immuno- and targeted-therapies in the management of primary and metastatic central nervous system malignancies.

Education

University of California, San Francisco, 06/14, Radiation Oncology
Brighman and Women's Hospital, 06/10, Internal Medicine
New York University School of Medicine, M.D., Ph.D., 06/09

Honors & Awards

  • 2020
    UCSF Rap Award
  • 2019
    ARRO Teacher of the Year Award
  • 2018
    UCSF Rap Award
  • 2017
    UCSF Radiation Oncology-Radiology Award
  • 2016
    ARRO Teacher of the Year Award
  • 2015
    UCSF Patient Care Fund Award
  • 2014
    RSNA Roetgen Research Award
  • 2013
    UCSF Exceptional Physician Award

Selected Publications

  1. Thomas NJ, Myall NJ, Sun F, Patil T, Mushtaq R, Yu C, Sinha S, Pollom EL, Nagpal S, Camidge DR, Rusthoven CG, Braunstein SE, Wakelee HA, McCoach CE. Brain Metastases in EGFR- and ALK-positive Non-Small Cell Lung Cancer: Outcomes of CNS Penetrant Tyrosine Kinase Inhibitors (TKIs) Alone versus in Combination with Radiation. J Thorac Oncol. 2021 Aug 26.  View on PubMed
  2. Chen WC, Baal UH, Baal JD, Pai JS, Boreta L, Braunstein SE, Raleigh DR. Efficacy and Safety of Stereotactic Radiosurgery for Brainstem Metastases: A Systematic Review and Meta-analysis. JAMA Oncol. 2021 Jul 01; 7(7):1033-1040.  View on PubMed
  3. Wu SY, Yee E, Vasudevan HN, Fogh SE, Boreta L, Braunstein SE, Hong JC. Risk Stratification for Imminent Risk of Death at the Time of Palliative Radiotherapy Consultation. JAMA Netw Open. 2021 Jul 01; 4(7):e2115641.  View on PubMed
  4. Ni L, Thomas HR, Raleigh DR, Boreta LC, Park CC, Braunstein SE. Residents-as-Teachers Curriculum for Radiation Oncology: A Targeted Needs Assessment. Int J Radiat Oncol Biol Phys. 2021 Jun 18.  View on PubMed
  5. Susko MS, Chen WC, Vasudevan HN, Magill ST, Lucas CG, Oberheim Bush NA, Solomon DA, Theodosopoulos PV, McDermott MW, Villanueva-Meyer JE, Boreta L, Nakamura JL, Sneed PK, Braunstein SE, Raleigh DR. Letter: Patterns of Intermediate- and High-Risk Meningioma Recurrence After Treatment With Postoperative External Beam Radiotherapy. Neurosurgery. 2021 06 15; 89(1):E99-E101.  View on PubMed
  6. Bush NAO, Young JS, Zhang Y, Dalle Ore CL, Molinaro AM, Taylor J, Clarke J, Prados M, Braunstein SE, Raleigh DR, Chang SM, Berger MS, Butowski NA. A single institution retrospective analysis on survival based on treatment paradigms for patients with anaplastic oligodendroglioma. J Neurooncol. 2021 Jul; 153(3):447-454.  View on PubMed
  7. Vargas E, Lockney DT, Mummaneni PV, Haddad AF, Rivera J, Tan X, Jamieson A, Mahmoudieh Y, Berven S, Braunstein SE, Chou D. An analysis of tumor-related potential spinal column instability (Spine Instability Neoplastic Scores 7-12) eventually requiring surgery with a 1-year follow-up. Neurosurg Focus. 2021 05; 50(5):E6.  View on PubMed
  8. Avadiappan S, Morrison MA, Jakary A, Felton E, Stoller S, Hess CP, Molinaro AM, Braunstein SE, Mueller S, Lupo JM. Relationship between 7T MR-angiography features of vascular injury and cognitive decline in young brain tumor patients treated with radiation therapy. J Neurooncol. 2021 May; 153(1):143-152.  View on PubMed
  9. Feng CH, Braunstein SE, MacEwan I. Utility of Multi-institutional Pediatric Chart Rounds in the Age of Telemedicine. Int J Radiat Oncol Biol Phys. 2021 Aug 01; 110(5):1272-1273.  View on PubMed
  10. Rosenberg DM, Braunstein SE, Fields EC, Gillespie EF, Gunther JR, Jimenez RB, Yechieli RL, Golden DW. Radiation Oncology Education Collaborative Study Group Annual Spring Symposium: Initial Impact and Feedback. J Cancer Educ. 2021 Mar 16.  View on PubMed
  11. Rudie JD, Weiss DA, Colby JB, Rauschecker AM, Laguna B, Braunstein S, Sugrue LP, Hess CP, Villanueva-Meyer JE. Three-dimensional U-Net Convolutional Neural Network for Detection and Segmentation of Intracranial Metastases. Radiol Artif Intell. 2021 May; 3(3):e200204.  View on PubMed
  12. Wu SY, Yee E, Chan JW, Chapman CH, Boreta L, Braunstein SE. Timing of Urgent Inpatient Palliative Radiation Therapy. Adv Radiat Oncol. 2021 May-Jun; 6(3):100670.  View on PubMed
  13. Zelefsky MJ, Yamada Y, Greco C, Lis E, Schöder H, Lobaugh S, Zhang Z, Braunstein S, Bilsky MH, Powell SN, Kolesnick R, Fuks Z. Phase 3 Multi-Center, Prospective, Randomized Trial Comparing Single-Dose 24 Gy Radiation Therapy to a 3-Fraction SBRT Regimen in the Treatment of Oligometastatic Cancer. Int J Radiat Oncol Biol Phys. 2021 Jul 01; 110(3):672-679.  View on PubMed
  14. Cheung JP, Morin O, Braunstein SE, Sneed PK, Theodosopoulos PV, McDermott MW, Ma L. Feasibility and Significance of Dose Adaptation via Linear Couch Translations to Correct for Rotational Shifts During Frameless Brain Radiosurgery with the Gamma Knife Icon™. Acta Neurochir Suppl. 2021; 128:145-150.  View on PubMed
  15. Ma L, Fogh S, Braunstein SE, Auguste K, Theodosopoulos PV, McDermott MW, Sneed PK. Impact of the Skull Size on the Normal Brain Radiation Dose During Gamma Knife Radiosurgery: Results of a Pilot Study. Acta Neurochir Suppl. 2021; 128:151-155.  View on PubMed
  16. Ma L, Braunstein SE, Golden E, Fogh S, Nakamura J, McDermott MW, Sneed PK. Redistributing Central Target Dose Hot Spots for Hypofractionated Radiosurgery of Large Brain Tumors: A Proof-of-Principle Study. Acta Neurochir Suppl. 2021; 128:101-106.  View on PubMed
  17. Nelson BA, Lapen K, Schultz O, Nangachiveettil J, Braunstein SE, Fernandez C, Fields EC, Gunther JR, Jeans E, Jimenez RB, Kharofa JR, Laucis A, Yechieli RL, Gillespie EF, Golden DW. The Radiation Oncology Education Collaborative Study Group 2020 Spring Symposium: Is Virtual the New Reality? Int J Radiat Oncol Biol Phys. 2021 06 01; 110(2):315-321.  View on PubMed
  18. Chen WC, Vasudevan HN, Choudhury A, Pekmezci M, Lucas CG, Phillips J, Magill ST, Susko MS, Braunstein SE, Oberheim Bush NA, Boreta L, Nakamura JL, Villanueva-Meyer JE, Sneed PK, Perry A, McDermott MW, Solomon DA, Theodosopoulos PV, Raleigh DR. A Prognostic Gene-Expression Signature and Risk Score for Meningioma Recurrence After Resection. Neurosurgery. 2020 12 15; 88(1):202-210.  View on PubMed
  19. Tinkle CL, Singh C, Lloyd S, Guo Y, Li Y, Pappo AS, DuBois SG, Lucas JT, Haas-Kogan DA, Terezakis SA, Braunstein SE, Krasin MJ. Stereotactic Body Radiation Therapy for Metastatic and Recurrent Solid Tumors in Children and Young Adults. Int J Radiat Oncol Biol Phys. 2021 04 01; 109(5):1396-1405.  View on PubMed
  20. Liu KX, Ioakeim-Ioannidou M, Susko MS, Rao AD, Yeap BY, Snijders AM, Ladra MM, Vogel J, Zaslowe-Dude C, Marcus KJ, Yock TI, Grassberger C, Braunstein SE, Haas-Kogan DA, Terezakis SA, MacDonald SM. A Multi-institutional Comparative Analysis of Proton and Photon Therapy-Induced Hematologic Toxicity in Patients With Medulloblastoma. Int J Radiat Oncol Biol Phys. 2021 03 01; 109(3):726-735.  View on PubMed

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