Research Summary

Dr. Braunstein is a radiation oncologist with a clinical interest in the treatment of pediatric, central nervous system, and soft tissue malignancies. He has expertise in modern radiation therapy techniques including stereotactic radiotherapy (Gamma Knife, Cyberknife, Linac-based SBRT), intraoperative radiotherapy, and intensity modulated radiation therapy.

Dr. Braunstein earned his M.D. at New York University School of Medicine where he also obtained a Ph.D. studying molecular pathways by which cancer cells mediate response to radiation. He currently serves as Vice Chair and Clinical Director of Radiation Oncology. His research focus includes mitigation of early and late toxicity in treatment of pediatric malignancies as well as optimizing combination of immuno- and targeted-therapies in the management of primary and metastatic central nervous system malignancies.

Education

University of California, San Francisco, 06/14, Radiation Oncology
Brighman and Women's Hospital, 06/10, Internal Medicine
New York University School of Medicine, M.D., Ph.D., 06/09

Honors & Awards

  • 2020
    UCSF Rap Award
  • 2019
    ARRO Teacher of the Year Award
  • 2018
    UCSF Rap Award
  • 2017
    UCSF Radiation Oncology-Radiology Award
  • 2016
    ARRO Teacher of the Year Award
  • 2015
    UCSF Patient Care Fund Award
  • 2014
    RSNA Roetgen Research Award
  • 2013
    UCSF Exceptional Physician Award

Selected Publications

  1. Zelefsky MJ, Yamada Y, Greco C, Lis E, Schöder H, Lobaugh S, Zhang Z, Braunstein S, Bilsky MH, Powell SN, Kolesnick R, Fuks Z Phase III Multi-Center, Prospective, Randomized Trial Comparing Single Dose 24 Gy Radiotherapy to a 3-Fraction SBRT Regimen in the Treatment of Oligometastatic Cancer.  View on PubMed
  2. Nelson BA, Lapen K, Schultz O, Nangachiveettil J, Braunstein SE, Fernandez C, Fields EC, Gunther JR, Jeans E, Jimenez RB, Kharofa JR, Laucis A, Yechieli RL, Gillespie EF, Golden DW The Radiation Oncology Education Collaborative Study Group 2020 Spring Symposium: Is Virtual the New Reality?  View on PubMed
  3. Chen WC, Vasudevan HN, Choudhury A, Pekmezci M, Lucas CG, Phillips J, Magill ST, Susko MS, Braunstein SE, Oberheim Bush NA, Boreta L, Nakamura JL, Villanueva-Meyer JE, Sneed PK, Perry A, McDermott MW, Solomon DA, Theodosopoulos PV, Raleigh DR A Prognostic Gene-Expression Signature and Risk Score for Meningioma Recurrence After Resection.  View on PubMed
  4. Tinkle CL, Singh C, Lloyd S, Guo Y, Li Y, Pappo AS, DuBois SG, Lucas JT, Haas-Kogan DA, Terezakis SA, Braunstein SE, Krasin MJ Stereotactic body radiotherapy for metastatic and recurrent solid tumors in children and young adults.  View on PubMed
  5. Liu KX, Ioakeim-Ioannidou M, Susko MS, Rao AD, Yeap BY, Snijders AM, Ladra MM, Vogel J, Zaslowe-Dude C, Marcus KJ, Yock TI, Grassberger C, Braunstein SE, Haas-Kogan DA, Terezakis SA, MacDonald SM A Multi-institutional Comparative Analysis of Proton and Photon Therapy-Induced Hematologic Toxicity in Patients With Medulloblastoma.  View on PubMed
  6. Lavergne V, Sabnis A, Tupule A, Davidson PR, Kline C, Matthay K, Nicolaides T, Goldsby R, Braunstein S, Fogh SE, Sneed PK, Menzel P, Nakamura A, DuBois SG, Haas-Kogan DA, Nakamura JL Germline MUTYH Mutation in a Pediatric Cancer Survivor Developing a Secondary Malignancy.  View on PubMed
  7. Sperduto PW, Mesko S, Li J, Cagney D, Aizer A, Lin NU, Nesbit E, Kruser TJ, Chan J, Braunstein S, Lee J, Kirkpatrick JP, Breen W, Brown PD, Shi D, Shih HA, Soliman H, Sahgal A, Shanley R, Sperduto W, Lou E, Everett A, Boggs DH, Masucci L, Roberge D, Remick J, Plichta K, Buatti JM, Jain S, Gaspar LE, Wu CC, Wang TJC, Bryant J, Chuong M, Yu J, Chiang V, Nakano T, Aoyama H, Mehta MP Estrogen/progesterone receptor and HER2 discordance between primary tumor and brain metastases in breast cancer and its effect on treatment and survival.  View on PubMed
  8. Gonzalez-Junca A, Reiners O, Borrero-Garcia LD, Beckford-Vera D, Lazar AA, Chou W, Braunstein S, VanBrocklin H, Franc BL, Barcellos-Hoff MH Positron Emission Tomography Imaging of Functional Transforming Growth Factor ß (TGFß) Activity and Benefit of TGFß Inhibition in Irradiated Intracranial Tumors.  View on PubMed
  9. Magill ST, Vasudevan HN, Seo K, Villanueva-Meyer JE, Choudhury A, John Liu S, Pekmezci M, Findakly S, Hilz S, Lastella S, Demaree B, Braunstein SE, Bush NAO, Aghi MK, Theodosopoulos PV, Sneed PK, Abate AR, Berger MS, McDermott MW, Lim DA, Ullian EM, Costello JF, Raleigh DR Multiplatform genomic profiling and magnetic resonance imaging identify mechanisms underlying intratumor heterogeneity in meningioma.  View on PubMed
  10. Aridgides P, Janssens GO, Braunstein S, Campbell S, Poppe M, Murphy E, MacDonald S, Ladra M, Alapetite C, Haas-Kogan D Gliomas, germ cell tumors, and craniopharyngioma.  View on PubMed
  11. Morrison MA, Mueller S, Felton E, Jakary A, Stoller S, Avadiappan S, Yuan J, Molinaro AM, Braunstein S, Banerjee A, Hess CP, Lupo JM Rate of radiation-induced microbleed formation on 7T MRI relates to cognitive impairment in young patients treated with radiation therapy for a brain tumor.  View on PubMed
  12. Sperduto PW, Mesko S, Li J, Cagney D, Aizer A, Lin NU, Nesbit E, Kruser TJ, Chan J, Braunstein S, Lee J, Kirkpatrick JP, Breen W, Brown PD, Shi D, Shih HA, Soliman H, Sahgal A, Shanley R, Sperduto WA, Lou E, Everett A, Boggs DH, Masucci L, Roberge D, Remick J, Plichta K, Buatti JM, Jain S, Gaspar LE, Wu CC, Wang TJC, Bryant J, Chuong M, An Y, Chiang V, Nakano T, Aoyama H, Mehta MP Survival in Patients With Brain Metastases: Summary Report on the Updated Diagnosis-Specific Graded Prognostic Assessment and Definition of the Eligibility Quotient.  View on PubMed
  13. Vargas E, Susko MS, Mummaneni PV, Braunstein SE, Chou D Vertebral body fracture rates after stereotactic body radiation therapy compared with external-beam radiation therapy for metastatic spine tumors.  View on PubMed
  14. Rusthoven CG, Yamamoto M, Bernhardt D, Smith DE, Gao D, Serizawa T, Yomo S, Aiyama H, Higuchi Y, Shuto T, Akabane A, Sato Y, Niranjan A, Faramand AM, Lunsford LD, McInerney J, Tuanquin LC, Zacharia BE, Chiang V, Singh C, Yu JB, Braunstein S, Mathieu D, Touchette CJ, Lee CC, Yang HC, Aizer AA, Cagney DN, Chan MD, Kondziolka D, Bernstein K, Silverman JS, Grills IS, Siddiqui ZA, Yuan JC, Sheehan JP, Cordeiro D, Nosaki K, Seto T, Deibert CP, Verma V, Day S, Halasz LM, Warnick RE, Trifiletti DM, Palmer JD, Attia A, Li B, Cifarelli CP, Brown PD, Vargo JA, Combs SE, Kessel KA, Rieken S, Patel S, Guckenberger M, Andratschke N, Kavanagh BD, Robin TP Evaluation of First-line Radiosurgery vs Whole-Brain Radiotherapy for Small Cell Lung Cancer Brain Metastases: The FIRE-SCLC Cohort Study.  View on PubMed
  15. Wu SY, Braunstein SE In Reply to Leung.  View on PubMed
  16. Liu KX, Naranjo A, Zhang FF, DuBois SG, Braunstein SE, Voss SD, Khanna G, London WB, Doski JJ, Geiger JD, Kreissman SG, Grupp SA, Diller LR, Park JR, Haas-Kogan DA Prospective Evaluation of Radiation Dose Escalation in Patients With High-Risk Neuroblastoma and Gross Residual Disease After Surgery: A Report From the Children's Oncology Group ANBL0532 Study.  View on PubMed
  17. Rooney MK, Rosenberg DM, Braunstein S, Cunha A, Damato AL, Ehler E, Pawlicki T, Robar J, Tatebe K, Golden DW Three-dimensional printing in radiation oncology: A systematic review of the literature.  View on PubMed
  18. Morshed RA, Winkler EA, Kim H, Braunstein S, Cooke DL, Hetts SW, Abla AA, Fullerton HJ, Gupta N High-Flow Vascular Malformations in Children.  View on PubMed
  19. Sloan EA, Hilz S, Gupta R, Cadwell C, Ramani B, Hofmann J, Kline CN, Banerjee A, Reddy A, Oberheim Bush NA, Chang S, Braunstein S, Chang EF, Raffel C, Gupta N, Sun PP, Kim JYH, Moes G, Alva E, Li R, Bruggers CS, Alashari M, Wetmore C, Garg S, Dishop M, Van Ziffle J, Onodera C, Devine P, Grenert JP, Lee JC, Phillips JJ, Pekmezci M, Tihan T, Bollen AW, Berger MS, Costello JF, Perry A, Solomon DA Gliomas arising in the setting of Li-Fraumeni syndrome stratify into two molecular subgroups with divergent clinicopathologic features.  View on PubMed
  20. Sperduto PW, Mesko S, Li J, Cagney D, Aizer A, Lin NU, Nesbit E, Kruser TJ, Chan J, Braunstein S, Lee J, Kirkpatrick JP, Breen W, Brown PD, Shi D, Shih HA, Soliman H, Sahgal A, Shanley R, Sperduto W, Lou E, Everett A, Boggs DH, Masucci L, Roberge D, Remick J, Plichta K, Buatti JM, Jain S, Gaspar LE, Wu CC, Wang TJC, Bryant J, Chuong M, Yu J, Chiang V, Nakano T, Aoyama H, Mehta MP Beyond an Updated Graded Prognostic Assessment (Breast GPA): A Prognostic Index and Trends in Treatment and Survival in Breast Cancer Brain Metastases From 1985 to Today.  View on PubMed

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