Education
University of California, Berkeley, B.A., 01/2006, Molecular and Cell Biology
New York University School of Medicine, M.D., 01/2015, Medicine
New York University Sackler Institute, Ph.D., 01/2013, Developmental Genetics
University of California, San Francisco, Resident, 01/2018, Anatomic Pathology
University of California, San Francisco, Fellow, 01/2018, Surgical Pathology
Honors & Awards
- 2002
Regents' Scholarship, University of California, Berkeley - 2005
Biology Fellows Program Semester Research Grant (Mentor: John Coates), University of California, Berkeley - 2007
Summer Scholarship for Medical Students (Mentor: Joel Ernst), Infectious Diseases Society of America - 2008
Award for Academic Excellence and Achievement, American Society of Clinical Pathology - 2011
3rd place poster prize, 18th International C. elegans Meeting, Genetics Society of America - 2016
Chief Resident, Department of Pathology, San Francisco VA Medical Center - 2016
Pathologist in Training Travel Award, 92nd Annual AANP Meeting, American Association of Neuropathologists - 2017
Chief Resident, Department of Pathology, San Francisco General Hospital - 2017
Pathologist in Training Travel Award, USCAP Annual Meeting, United States and Canadian Academy of Pathology - 2017
Visiting scholar. Genitourinary pathology. Mentor: Victor Reuter. 1 month., Memorial Sloan Kettering Cancer Center - 2018
Visiting scholar. Genitourinary pathology. Mentor Jesse McKenney. 1 month., Cleveland Clinic
Selected Publications
- Papanicolau-Sengos A, Singh O, Park K, Snuderl M, Tretiakova M, Merino M, Stohr B, Simko J, Deng FM, Chan E, Wu J, Barreto J, Gupta R, Park B, Turakulov R, Abdullaev Z, Solomon D, Aldape K DNA methylation-based classification of kidney neoplasms. View on PubMed
- Chang K, Delavan HM, Yip E, Kasap C, Zhu J, Lodha R, Liao SY, Berman SC, Carretero-Gonzalez A, Basar M, Gokturk Ozcan G, Teo MY, Solit DB, Rosenberg JE, Al-Ahmadie H, Ding CCK, Chan E, Steri V, Porten SP, Koshkin VS, Friedlander TW, Feng FY, Lee JK, Wiita AP, Chu CE, Chou J Modulating the PPAR? pathway upregulates NECTIN4 and enhances chimeric antigen receptor (CAR) T cell therapy in bladder cancer. View on PubMed
- Sirohi D, Cornelia Ding CK, Stohr BA, Balassanian R, Vohra P, Aggarwal R, Chan E, Greenland NY The utility of next-generation sequencing in metastatic prostate cancer FNA biopsies. View on PubMed
- Rizkalla CN, Tretiakova M, Suarez CJ, Williamson SR, Al-Obaidy KI, Acosta AM, Idrees MT, Chan E, Potterveld S, Sangoi AR Urothelial carcinoma with osteoclast-like giant cells: An expanded immunohistochemical and molecular profile. View on PubMed
- Rizkalla CN, Tretiakova M, Williamson SR, Akgul M, Al-Obaidy KI, Acosta AM, Idrees MT, Chan E, Sangoi AR Overlapping Morphologic and Immunophenotypic Features of Plasmacytoid Urothelial Carcinoma and Urothelial Carcinoma With Osteoclast-Like Giant Cells. View on PubMed
- Modest DP, Fakih M, Salvatore L, Esaki T, Lopez-Bravo DP, Taieb J, Karamouzis M, Ruiz-Garcia E, Kim TW, Kuboki Y, Meriggi F, Cunningham D, Yeh KH, Cremolini C, Tran Q, Chan E, Chao J, Majer IM, Pietrantonio F Health-related quality of life in patients with KRASG12C-mutated chemorefractory metastatic colorectal cancer treated with sotorasib plus panitumumab or standard of care (CodeBreaK 300): results from a phase 3, randomised clinical trial. View on PubMed
- Gao H, Ren D, Giannico GA, Akgul M, Khani F, Galea LA, Al-Obaidy KI, Falzarano SM, Wobker SE, Barry-Holson KQ, Chan E, McHenry AJ, Sangoi AR Do urinary bladder smooth muscle neoplasms show morphologic and immunophenotypic features of their uterine fumarate hydratase-deficient counterparts? View on PubMed
- Chan E, Stohr BA, Sangoi AR, Sirohi D Invasive urothelial carcinoma with chordoid and myxoid features shows increased RAS/RAF pathway alterations. View on PubMed
- Sangoi AR, Akgul M, Mubeen A, Humble R, Wu DJ, Pacheco R, Acosta A, Amin M, Aron M, Brimo F, Chan E, Cheng L, Cheville J, Collins K, Cornejo K, Dhillon J, Downes MR, Epstein JI, Hirsch M, Kapur P, Lobo A, Mehra R, Mohanty S, Netto G, Osunkoya AO, Paner G, Rao P, Saleeb R, Shah RB, Shen S, Smith S, Tickoo S, Tretiakova M, Trpkov K, Wobker S, Tamboli P, Zynger D, Williamson SR Interobserver Reproducibility of Pelvicalyceal Invasion in Renal Cell Carcinoma Nephrectomies Among Genitourinary Pathologists. View on PubMed
- Chan E, Pugh SL, Simko JP, Feng F, Shipley WU, Lukka HR, Bahary JP, Pisansky TM, Zeitzer KL, Gore E, Efstathiou JA, Rosenthal SA, Balogh AG, Lovett RD, Wong A, Dess RT, McGinnis LS, Kuettel M, DeMora L, Sandler HM Prognostic Impact of Lymph Node Yield in a Phase III Clinical Trial (NRG/RTOG 9601) of Prostate Cancer Patients Treated With Salvage Radiation Following Prostatectomy. View on PubMed
- Shahabi A, Konstantinov A, McKenney JK, Lane J, Kao CS, Williamson SR, Alaghehbandan R, Cheng L, Sangoi AR, Chan E, Cornejo KM, Przybycin CG Serous Borderline Tumors of the Testis and Paratestis: A Clinicopathologic Study of 19 Tumors Emphasizing Morphologic Spectrum and Clinical Outcome. View on PubMed
- Nourbakshs M, Du L, Acosta AM, Alaghehbandan R, Amin A, Amin MB, Aron M, Berney D, Brimo F, Chan E, Cheng L, Colecchia M, Dhillon J, Downes MR, Evans AJ, Harik LR, Hassan O, Haider A, Humphrey PA, Jha S, Kandukuri S, Kao CS, Kaushal S, Khani F, Kryvenko ON, Kweldam C, Lal P, Lobo A, Maclean F, Magi-Galluzzi C, Mehra R, Miyamoto H, Mohanty SK, Montironi R, Nesi G, Netto GJ, Nguyen JK, Nourieh M, Osunkoya AO, Paner GP, Sangoi AR, Shah RB, Srigley JR, Tretiakova M, Troncoso P, Trpkov K, Van Der Kwast TH, Zhang M, Zynger DL, Williamson SR, Giannico GA Current practices in prostate pathology reporting: results from a survey of genitourinary and general pathologists. View on PubMed
- Koshkin VS, Schafer JM, Scherrer E, Boyiddle C, Schwartz NRM, Yu H, Fang Q, Baker AF, Sayedian FH, Chan E Testing and Interpretation of Human Epidermal Growth Factor Receptor 2 Protein Expression and ERBB2 Gene Amplification in Advanced Urothelial Carcinoma. View on PubMed
- Pietrantonio F, Salvatore L, Esaki T, Modest DP, Lopez-Bravo DP, Taieb J, Karamouzis MV, Ruiz-Garcia E, Kim TW, Kuboki Y, Meriggi F, Cunningham D, Yeh KH, Chan E, Chao J, Tran Q, Cremolini C, Fakih M Overall Survival Analysis of the Phase III CodeBreaK 300 Study of Sotorasib Plus Panitumumab Versus Investigator's Choice in Chemorefractory KRAS G12C Colorectal Cancer. View on PubMed
- Glover M, Beshar I, McHenry A, Ding C, Dorigo O, Chan E, Shah SA Clinical Response to Enfortumab Vedotin and Pembrolizumab in a Patient with Vaginal Squamous Cell Carcinoma: A Case Report. View on PubMed
- Cheng AV, Wu DJ, Friedman LA, Chan E, Williamson SR, Galea LA, Sangoi AR. MAPK1IP1L::TFE3-rearranged renal cell carcinoma: a novel fusion adding to the differential diagnosis of oncocytic renal neoplasms. Virchows Arch. 2025 Jan 25. View on PubMed
- Theparee T, Umetsu SE, Chan E Pancreatic Serous Neoplasm and Metastatic Clear Cell Renal Cell Carcinoma: Diagnostic Pitfalls Resolvable by a Panel of Immunohistochemical Stains to Include PAX8 and CK7 But Not CAIX. View on PubMed
- Mubeen A, Pacheco R, Akgul M, Williamson SR, Collins K, Chan E, Sangoi AR. Gamna-Gandy bodies in renal neoplasms: A multi-institutional clinicopathologic study of 350 consecutive nephrectomies. Ann Diagn Pathol. 2025 Jan 14; 75:152440. View on PubMed
- Kayraklioglu N, Stohr BA, Chan E. Clinicopathologic and Molecular Characterization of High-Risk Human Papillomavirus-Positive Carcinomas of the Urinary Tract. Arch Pathol Lab Med. 2025 Jan 01; 149(1):30-38. View on PubMed
- Bernhardt M, Weinhold L, Bremmer F, Chan E, Cheng L, Collins K, Downes M, Greenland N, Hommerding O, Iczkowski KA, Jufe L, Kreft T, van Leenders G, Oxley J, Perry-Keene J, Reis H, Schmid M, Tsuzuki T, Wobker S, Wiliamson SR, Kweldam C, Kristiansen G. Unexpectedly high variability in determining tumour extent in prostatic biopsies: implications for active surveillance. Histopathology. 2025 Mar; 86(4):627-639. View on PubMed