John de Groot, MD
Professor and Chief, Division of Neuro-Oncology, Department of Neurosurgery, UCSF
Dr. John de Groot is a neuro-oncologist specializing in the diagnosis and management of patients with primary brain and spine tumors. Dr. de Groot comes to UCSF from MD Anderson Cancer Center in Houston, Texas, where he served as director of clinical research in neuro-oncology (2013-2021) and interim chair of the Department of Neuro-Oncology (2015-2020). He joined the faculty at MD Anderson in 2004 after completing a neuro-oncology fellowship there. Dr. de Groot completed his neurology residency at Johns Hopkins University and received his medical degree from the University of Texas Medical Branch at Galveston.
Dr. de Groot is experienced in bringing new therapies from the laboratory into the clinic for treating patients with brain cancer. He has contributed to the clinical development of antiangiogenic, molecularly targeted and immunotherapy treatments for glioblastoma, and he regularly advises and collaborates with other researchers on new and developing therapies. Dr. de Groot is especially interested in the use of blood, imaging and other indirect biomarkers to evaluate the efficacy of novel therapies and is studying new approaches to overcome limitations in drug delivery to brain tumors such as through use of focused ultrasound.