Research Summary

Dr. Shawn Hervey-Jumper is a neurosurgeon with subspecialty focus on neuro-oncology. His clinical practice is focused on the surgical management of patients with brain cancer within functional areas using physiological mapping. Dr. Hervey-Jumper's research focuses on the mechanisms by which intrinsic brain tumors, such as low- and high-grade gliomas, interface with neural networks and how repair of these networks impacts cognition. Though the survival of some may be short, it is increasingly understood that many glioma patients will survive for years with extensive language, motor, and cognitive disabilities that impact the quality of their lives. Despite the prevailing assumption that gliomas represent an ablative process, we now know that interactions between glioma cells and the neuronal microenvironment influence tumor growth, invasiveness, and potentially cognition. In his research laboratory he uses neurophysiology in order to address questions in human cognition as well as tumor-network dynamics.

Research Funding

  • May 1, 2019 - April 30, 2024 - Intratumoral functional connectivity with implications on synaptogenesis and aphasia recovery in adult astrocytic WHO II-III glioma, Principal Investigator. Sponsor: NINDS, Sponsor Award ID: 1K08NS110919-01
  • February 1, 2018 - February 28, 2023 - IDH1 Mutant Glioma Model: Tumor Progression and Impact on Therapeutics, Co-Investigator. Sponsor: NINDS, Sponsor Award ID: P0523121
  • July 1, 2017 - July 1, 2021 - The consequences of brain irradiation on white matter repair and language pathways reorganization in adult glioma, Principal Investigator. Sponsor: Robert Wood Johnson Foundation, Sponsor Award ID: 74259
  • July 1, 2017 - June 30, 2020 - Neurogenesis mediated Aphasia Recovery in Adult High Grade Glioma, Principal Investigator. Sponsor: University of California San Francisco, Sponsor Award ID: Dean's Diversity Fund

Education

Oakwood College, Huntsville, AL, B.S., 05/2001, Biology
The Ohio State University, Columbus, OH, M.D., 06/2006,Medicine
University of Michigan, Ann Arbor, MI, Internship, 06/2007, Transitional
University of Michigan, Ann Arbor, MI, Research Fellowship, 01/2012, Neuro-Oncology
University of Michigan, Ann Arbor, MI, Resident, 06/2012, Neurosurgery
University of Michigan, Ann Arbor, MI, Chief Resident, 06/2013, Neurosurgery
University of California San Francisco, SF, CA, Clinical Fellowship, 06/2014, Neuro-Oncology

Honors & Awards

  • 2005
    Alpha Omega Alpha Medical Honors Society, Ohio State University
  • 2005
    Gold Humanism Honor Society, The Ohio State University
  • 2006
    Landacre Research Honors Society, Ohio State University
  • 2006
    Watchman Achievement Award, Alpha Omega Alpha Medical Honors Society
  • 2007
    National Scholars Honor Society, The Ohio State University
  • 2007
    Arnold G. Coran Teaching Award, University of Michigan
  • 2010
    Health Policy Scholar, Ruben J Williams (RJW) Foundation
  • 2011
    Wilder Penfield Award, Congress of Neurological Surgeons
  • 2011
    NREF/AAcNS Research Award
  • 2013
    Chandler-McGillicuddy leadership award, University of Michigan
  • 2013
    Max Peet Teaching Award, University of Michigan
  • 2014
    Ronald L. Bittner Award in Brain Tumor Research, AANS/CNS Section on Tumors
  • 2016
    Alfred Taubman Medical Research Institute Emerging Scholar
  • 2017
    Robert Wood Johnson Foundation Harold Amos Fellow
  • 2017
    John A. Watson Faculty Scholar

Selected Publications

  1. Ammanuel SG, Edwards CS, Chan AK, Mummaneni PV, Kidane J, Vargas E, D'Souza S, Nichols AD, Sankaran S, Abla AA, Aghi MK, Chang EF, Hervey-Jumper SL, Kunwar S, Larson PS, Lawton MT, Starr PA, Theodosopoulos PV, Berger MS, McDermott MW Are preoperative chlorhexidine gluconate showers associated with a reduction in surgical site infection following craniotomy? A retrospective cohort analysis of 3126 surgical procedures.  View on PubMed
  2. Aabedi AA, Kakaizada S, Young JS, Kaur J, Wiese O, Valdivia C, Krishna S, Weyer-Jamora C, Berger MS, Weissman DH, Brang D, Hervey-Jumper SL Convergence of heteromodal lexical retrieval in the lateral prefrontal cortex.  View on PubMed
  3. Porter AB, Chukwueke UN, Mammoser AG, Friday B, Hervey-Jumper S Delivering Equitable Care to Underserved Neuro-oncology Populations.  View on PubMed
  4. Przybylowski CJ, Hervey-Jumper SL, Sanai N Surgical strategy for insular glioma.  View on PubMed
  5. Weyer-Jamora C, Brie MS, Luks TL, Smith EM, Hervey-Jumper SL, Taylor JW Postacute Cognitive Rehabilitation for Adult Brain Tumor Patients.  View on PubMed
  6. Mischkulnig M, Kiesel B, Lötsch D, Roetzer T, Borkovec M, Wadiura LI, Roessler K, Hervey-Jumper S, Penninger JM, Berger MS, Widhalm G, Erhart F Heme Biosynthesis mRNA Expression Signature: Towards a Novel Prognostic Biomarker in Patients with Diffusely Infiltrating Gliomas.  View on PubMed
  7. De Witt Hamer PC, De Witt Hamer PC, Klein M, Hervey-Jumper SL, Wefel JS, Berger MS Functional Outcomes and Health-Related Quality of Life Following Glioma Surgery.  View on PubMed
  8. Krishna S, Kakaizada S, Almeida N, Brang D, Hervey-Jumper S Central Nervous System Plasticity Influences Language and Cognitive Recovery in Adult Glioma.  View on PubMed
  9. Morshed RA, Young JS, Hervey-Jumper SL Commentary: Planning Brain Tumor Resection Using a Probabilistic Atlas of Cortical and Subcortical Structures Critical for Functional Processing: A Proof of Concept.  View on PubMed
  10. Young JS, Gogos AJ, Pereira MP, Morshed RA, Li J, Barkovich MJ, Hervey-Jumper SL, Berger MS Effects of ventricular entry on patient outcome during glioblastoma resection.  View on PubMed
  11. Morshed RA, Young JS, Kroliczek AA, Berger MS, Brang D, Hervey-Jumper SL A Neurosurgeon's Guide to Cognitive Dysfunction in Adult Glioma.  View on PubMed
  12. Morshed RA, Young JS, Lee AT, Berger MS, Hervey-Jumper SL Clinical Pearls and Methods for Intraoperative Awake Language Mapping.  View on PubMed
  13. Muster RH, Young JS, Woo PYM, Morshed RA, Warrier G, Kakaizada S, Molinaro AM, Berger MS, Hervey-Jumper SL The Relationship Between Stimulation Current and Functional Site Localization During Brain Mapping.  View on PubMed
  14. Morshed RA, Young JS, Lee AT, Hervey-Jumper SL Functional Mapping for Glioma Surgery, Part 2: Intraoperative Mapping Tools.  View on PubMed
  15. Weyer-Jamora C, Brie MS, Luks TL, Smith EM, Braunstein SE, Villanueva-Meyer JE, Bracci PM, Chang S, Hervey-Jumper SL, Taylor JW Cognitive impact of lower-grade gliomas and strategies for rehabilitation.  View on PubMed
  16. Schulte JD, Buerki RA, Lapointe S, Molinaro AM, Zhang Y, Villanueva-Meyer JE, Perry A, Phillips JJ, Tihan T, Bollen AW, Pekmezci M, Butowski N, Oberheim Bush NA, Taylor JW, Chang SM, Theodosopoulos P, Aghi MK, Hervey-Jumper SL, Berger MS, Solomon DA, Clarke JL Clinical, radiologic, and genetic characteristics of histone H3 K27M-mutant diffuse midline gliomas in adults.  View on PubMed
  17. Gogos AJ, Young JS, Pereira MP, Morshed RA, Potts MB, Hervey-Jumper SL, Berger MS Surgical management of incidentally discovered low-grade gliomas.  View on PubMed
  18. Eijgelaar RS, Visser M, Müller DMJ, Barkhof F, Vrenken H, van Herk M, Bello L, Conti Nibali M, Rossi M, Sciortino T, Berger MS, Hervey-Jumper S, Kiesel B, Widhalm G, Furtner J, Robe PAJT, Mandonnet E, De Witt Hamer PC, de Munck JC, Witte MG Robust Deep Learning-based Segmentation of Glioblastoma on Routine Clinical MRI Scans Using Sparsified Training.  View on PubMed
  19. Zhang JJY, Lee KS, Voisin MR, Hervey-Jumper SL, Berger MS, Zadeh G Awake craniotomy for resection of supratentorial glioblastoma: a systematic review and meta-analysis.  View on PubMed
  20. Kim EE, Klein AL, Lartigue JW, Hervey-Jumper SL, Rosseau G Diversity in Neurosurgery.  View on PubMed

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