Research Summary

Gerald Hsu, MD PhD is an Associate Clinical Professor of Medicine in the Department of Medicine at UCSF. He practices Hematology/Oncology at the San Francisco VA Medical Center and is active in medical education of Medicine Residents. Dr. Hsu is the Hematology/Oncology Fellowship Program Director.

Education

University of Toronto, Toronto, Canada Hons. BSc. 06/1997 Physiology Duke University School of Medicine M.D 06/2005 Duke University School of Medicine Ph.D. 06/2005 Biochemistry (Lorena Beese, PhD) Brigham & Women's Hospital, Boston, MA Intern 06/2006 Medicine Brigham & Women's Hospital, Boston, MA Resident 06/2008 Medicine University of California, San Francisco Fellow 06/2011 Medical Oncology Brigham & Women's Hospital, Boston, MA Chief Resident 06/2012 Medicine

Honors & Awards

  • 2008
    Resident Mentor Award, Brigham & Women's Hospital, Department of Medicine
  • 2014
    Hematology and Oncology Teaching Award, Department of Medicine, Division of Hematology/Oncology
  • 2015
    Excellence in Teaching Award, Academy of Medical Educators, University of California, San Francisco
  • 2016
    Essential Core Teaching Award - Excellence in Small Group Instruction, School of Medicine, University of California San Francisco
  • 2016
    Haile T. Debas Academy of Medical Educators - Inductee, University of California San Francisco

Selected Publications

  1. Wiita AP, Hsu GW, Lu CM, Esensten JH, Wells JA. Circulating proteolytic signatures of chemotherapy-induced cell death in humans discovered by N-terminal labeling. Proc Natl Acad Sci U S A. 2014 May 27; 111(21):7594-9.  View on PubMed
  2. Crawford ED, Seaman JE, Agard N, Hsu GW, Julien O, Mahrus S, Nguyen H, Shimbo K, Yoshihara HA, Zhuang M, Chalkley RJ, Wells JA. The DegraBase: a database of proteolysis in healthy and apoptotic human cells. Mol Cell Proteomics. 2013 Mar; 12(3):813-24.  View on PubMed
  3. Shimbo K, Hsu GW, Nguyen H, Mahrus S, Trinidad JC, Burlingame AL, Wells JA. Quantitative profiling of caspase-cleaved substrates reveals different drug-induced and cell-type patterns in apoptosis. Proc Natl Acad Sci U S A. 2012 Jul 31; 109(31):12432-7.  View on PubMed
  4. Büsch F, Pieck JC, Ober M, Gierlich J, Hsu GW, Beese LS, Carell T. Dissecting the differences between the alpha and beta anomers of the oxidative DNA lesion FaPydG. Chemistry. 2008; 14(7):2125-32.  View on PubMed
  5. Hsu GW, Huang X, Luneva NP, Geacintov NE, Beese LS. Structure of a high fidelity DNA polymerase bound to a benzo[a]pyrene adduct that blocks replication. J Biol Chem. 2005 Feb 04; 280(5):3764-70.  View on PubMed
  6. Hsu GW, Kiefer JR, Burnouf D, Becherel OJ, Fuchs RP, Beese LS. Observing translesion synthesis of an aromatic amine DNA adduct by a high-fidelity DNA polymerase. J Biol Chem. 2004 Nov 26; 279(48):50280-5.  View on PubMed
  7. Hsu GW, Ober M, Carell T, Beese LS. Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase. Nature. 2004 Sep 09; 431(7005):217-21.  View on PubMed

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