Laura Huppert, MD

Assistant Professor, Division of Hematology/Oncology, Department of Medicine, UCSF

Cancer Center Program Membership

Breast Oncology


  • Harvard College B.A. 09/2006 05/2010 Molecular and Cellular Biology
  • Harvard Medical School M.D. 09/2011 05/2015 Medicine
  • University of California, San Francisco Residency 07/2015 06/2018 Internal Medicine
  • University of California, San Francisco Fellowship 07/2019 06/2022 Medical Hematology and Oncology

Honors & Awards

  • 2022 ASCO Merit Award
  • 2021 UCSF Internal Medicine Residency Fellow of the Year Award
  • 2021 UCSF Graduate Medical Education Excellence and Innovation Award
  • 2020 UCSF Hematology/Oncology Clinical Fellow of the Year Award  

Selected Publications

  1. Huppert LA, Daud AI. Intratumoral therapies and in-situ vaccination for melanoma. Hum Vaccin Immunother. 2022 05 31; 18(3):1890512.  View on PubMed
  2. Huppert LA, Gumusay O, Rugo HS. Emerging treatment strategies for metastatic triple-negative breast cancer. Ther Adv Med Oncol. 2022; 14:17588359221086916.  View on PubMed
  3. Gumusay O, Huppert LA, Behr SC, Rugo HS. The role of percutaneous vertebral augmentation in patients with metastatic breast cancer: Literature review including report of two cases. Breast. 2022 Jun; 63:149-156.  View on PubMed
  4. Isaza E, Huppert LA, Lai AR, Brondfield S. Tumor Fever Due to Metastatic Esophageal Squamous Cell Carcinoma. Am J Med. 2022 08; 135(8):e294-e295.  View on PubMed
  5. Huppert LA, Babik JM. Development and Evaluation of a Five-Component Toolkit for Internal Medicine Residents Applying for Subspecialty Fellowships. MedEdPORTAL. 2022; 18:11228.  View on PubMed
  6. Huppert LA, Hsu G, Elnachef N, Flint L, Frank JA, Gensler LS, Hsiao EC, Khanna RR, Qasim A, Schwartz BS, Widera E, Zapata C, Babik JM. A single center evaluation of applicant experiences in virtual interviews across eight internal medicine subspecialty fellowship programs. Med Educ Online. 2021 Dec; 26(1):1946237.  View on PubMed
  7. Huppert LA, Mariotti V, Chien AJ, Soliman HH. Emerging immunotherapeutic strategies for the treatment of breast cancer. Breast Cancer Res Treat. 2022 Jan; 191(2):243-255.  View on PubMed
  8. Roberts HJ, Huppert LA. Reply to Letter to the Editor: The Effect of COVID-19 on the Orthopaedic Surgery Residency Application Process. J Am Acad Orthop Surg. 2021 Sep 16.  View on PubMed
  9. Huppert LA, Green MD, Kim L, Chow C, Leyfman Y, Daud AI, Lee JC. Tissue-specific Tregs in cancer metastasis: opportunities for precision immunotherapy. Cell Mol Immunol. 2022 01; 19(1):33-45.  View on PubMed
  10. Lee JC, Green MD, Huppert LA, Chow C, Pierce RH, Daud AI. The Liver-Immunity Nexus and Cancer Immunotherapy. Clin Cancer Res. 2022 01 01; 28(1):5-12.  View on PubMed
  11. Huppert LA, Daud AI. Pembrolizumab and Ipilimumab as Second-Line Therapy for Advanced Melanoma. J Clin Oncol. 2021 08 20; 39(24):2637-2639.  View on PubMed
  12. Rugo HS, Huppert L. Answers Are in the Blood: cfDNA to Enhance Precision Medicine for Breast Cancer. Clin Cancer Res. 2021 06 15; 27(12):3275-3277.  View on PubMed
  13. Huppert LA, Santhosh L, Babik JM. Trends in US Internal Medicine Residency and Fellowship Applications During the COVID-19 Pandemic vs Previous Years. JAMA Netw Open. 2021 04 01; 4(4):e218199.  View on PubMed
  14. Huppert LA, Hsiao EC, Cho KC, Marquez C, Chaudhry RI, Frank J, Goglin SE, Hsu G, Kathpalia P, Khanna R, Kompala T, Rao MN, Bower BA, Trafas V, Santhosh L, Schwartz BS, Babik JM. Virtual Interviews at Graduate Medical Education Training Programs: Determining Evidence-Based Best Practices. Acad Med. 2021 08 01; 96(8):1137-1145.  View on PubMed
  15. Huppert LA, Babik JM. Best Practices to Successfully Navigate a Virtual Interview: a Five-Step Guide for Hematology/Oncology Fellowship Applicants. J Cancer Educ. 2020 10; 35(5):860-861.  View on PubMed
  16. Huppert LA, Melisko ME, Glastonbury CM, Khanafshar E, Daud AI. Treatment of Metastatic Melanoma With Leptomeningeal Disease Using Intrathecal Immunotherapy. JCO Oncol Pract. 2020 11; 16(11):757-759.  View on PubMed
  17. Huppert LA, Gordan JD, Kelley RK. Checkpoint Inhibitors for the Treatment of Advanced Hepatocellular Carcinoma. Clin Liver Dis (Hoboken). 2020 Feb; 15(2):53-58.  View on PubMed
  18. Twitty CG, Huppert LA, Daud AI. Prognostic Biomarkers for Melanoma Immunotherapy. Curr Oncol Rep. 2020 02 11; 22(3):25.  View on PubMed
  19. Huppert LA, Matthay MA, Ware LB. Pathogenesis of Acute Respiratory Distress Syndrome. Semin Respir Crit Care Med. 2019 02; 40(1):31-39.  View on PubMed
  20. Huppert LA, Liu KD, Matthay MA. Therapeutic potential of mesenchymal stromal cells in the treatment of ARDS. Transfusion. 2019 02; 59(S1):869-875.  View on PubMed

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