Research Funding

  • July 1, 1979 - June 30, 2021 - Cell Biology, Genetics, and Biochemistry Training Grant, Principal Investigator. Sponsor: NIH/NIGMS, Sponsor Award ID: T32GM007810
  • July 1, 2009 - November 30, 2020 - The transcriptional circuitry controlling biofilm development in Candida albicans, Principal Investigator. Sponsor: NIH, Sponsor Award ID: R01AI083311
  • August 1, 1986 - March 31, 2019 - Mechanism of Yeast Transcriptional Regulators, Principal Investigator. Sponsor: NIH, Sponsor Award ID: R01GM037049
  • March 1, 2001 - November 30, 2016 - Regulatory Circuits and Virulence in Candida albicans, Principal Investigator. Sponsor: NIH, Sponsor Award ID: R01AI049187

Education

Vanderbilt University, Nashville TN, B.A., 1974, Biochemistry
Harvard University, Cambridge MA, M.A., Ph.D., 1980, Biochemistry
University of California, San Francisco, Postdoctoral, 1981-85, Biochemistry

Honors & Awards

  • B.A. summa cum laude, 1974
  • Phi Beta Kappa, 1974
  • Dreyfus Scholarship, 1974-1977
  • Damon Runyon-Walter Winchell Postdoctoral Fellowship, 1981-1983
  • Pew Scholarship, 1986-1990
  • Elected to American Academy of Microbiology, 1998
  • Burroughs Wellcome Merit Award, 1999 - 2004
  • Ellison Medical Foundation Senior Scholar in Global Infectious Diseases, 2004-2008
  • Elected to American Academy of Arts and Sciences, 2007
  • The Emil Christian Hansen Award for Microbiology, 2009
  • Elected to the National Academy of Sciences, 2011

Selected Publications

  1. Lohse MB, Ennis CL, Hartooni N, Johnson AD, Nobile CJ A Screen for Small Molecules to Target Candida albicans Biofilms.  View on PubMed
  2. Lohse MB, Brenes LR, Ziv N, Winter MB, Craik CS, Johnson AD An Opaque Cell-Specific Expression Program of Secreted Proteases and Transporters Allows Cell-Type Cooperation in Candida albicans.  View on PubMed
  3. Brenes LR, Lohse MB, Hartooni N, Johnson AD A Set of Diverse Genes Influence the Frequency of White-Opaque Switching in Candida albicans.  View on PubMed
  4. Lohse MB, Gulati M, Craik CS, Johnson AD, Nobile CJ Combination of Antifungal Drugs and Protease Inhibitors Prevent Candida albicans Biofilm Formation and Disrupt Mature Biofilms.  View on PubMed
  5. Nobile CJ, Ennis CL, Hartooni N, Johnson AD, Lohse MB A Selective Serotonin Reuptake Inhibitor, a Proton Pump Inhibitor, and Two Calcium Channel Blockers Inhibit Candida albicans Biofilms.  View on PubMed
  6. Mancera E, Frazer C, Porman AM, Ruiz-Castro S, Johnson AD, Bennett RJ Corrigendum: Genetic Modification of Closely Related Candida Species.  View on PubMed
  7. Britton CS, Sorrells TR, Johnson AD Protein-coding changes preceded cis-regulatory gains in a newly evolved transcription circuit.  View on PubMed
  8. Dalal CK, Zuleta IA, Lohse MB, Zordan RE, El-Samad H, Johnson AD A population shift between two heritable cell types of the pathogen Candida albicans is based both on switching and selective proliferation.  View on PubMed
  9. Takagi J, Singh-Babak SD, Lohse MB, Dalal CK, Johnson AD Candida albicans white and opaque cells exhibit distinct spectra of organ colonization in mouse models of infection.  View on PubMed
  10. Mancera E, Frazer C, Porman AM, Ruiz-Castro S, Johnson AD, Bennett RJ Genetic Modification of Closely Related Candida Species.  View on PubMed
  11. Sorrells TR, Johnson AN, Howard CJ, Britton CS, Fowler KR, Feigerle JT, Weil PA, Johnson AD Intrinsic cooperativity potentiates parallel cis-regulatory evolution.  View on PubMed
  12. Johnson AD The rewiring of transcription circuits in evolution.  View on PubMed
  13. Lohse MB, Gulati M, Johnson AD, Nobile CJ Development and regulation of single- and multi-species Candida albicans biofilms.  View on PubMed
  14. Craik VB, Johnson AD, Lohse MB Sensitivity of White and Opaque Candida albicans Cells to Antifungal Drugs.  View on PubMed
  15. Dalal CK, Johnson AD How transcription circuits explore alternative architectures while maintaining overall circuit output.  View on PubMed
  16. Lohse MB, Gulati M, Valle Arevalo A, Fishburn A, Johnson AD, Nobile CJ Assessment and Optimizations of Candida albicans In Vitro Biofilm Assays.  View on PubMed
  17. Nocedal I, Mancera E, Johnson AD Gene regulatory network plasticity predates a switch in function of a conserved transcription regulator.  View on PubMed
  18. Guajardo I, Ayer A, Johnson AD, Ganz P, Mills C, Donovan C, Scherzer R, Shah SJ, Peralta CA, Dubin RF Sex differences in vascular dysfunction and cardiovascular outcomes: The cardiac, endothelial function, and arterial stiffness in ESRD (CERES) study.  View on PubMed
  19. Ene IV, Lohse MB, Vladu AV, Morschhäuser J, Johnson AD, Bennett RJ Phenotypic Profiling Reveals that Candida albicans Opaque Cells Represent a Metabolically Specialized Cell State Compared to Default White Cells.  View on PubMed
  20. Winter MB, Salcedo EC, Lohse MB, Hartooni N, Gulati M, Sanchez H, Takagi J, Hube B, Andes DR, Johnson AD, Craik CS, Nobile CJ Global Identification of Biofilm-Specific Proteolysis in Candida albicans.  View on PubMed

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