Research Summary

Dr. Jasleen Kukreja is a cardiothoracic surgeon and director of the Lung Transplant Program at UCSF Medical Center. She is also director of the adult respiratory mechanical circulatory support program. She performs lung transplant surgery and lung volume reduction surgery for emphysema, and treats patients with tumors of the chest, including lung cancer, esophageal cancer, mediastinal tumors and mesothelioma.

Kukreja is the associate director of UCSF's lung transplant research division of cardiothoracic surgery.

Kukreja earned a medical degree at the David Geffen School of Medicine at UCLA. She completed residencies in general surgery at Brigham and Women's Hospital in Boston and in cardiothoracic surgery at UCSF. She completed fellowships in general surgery and thoracic surgery at Brigham and Women's Hospital, and also completed extensive training in designing clinical trials, studies that evaluate potential treatments' safety and efficacy. She has a master's degree in public health from the Harvard T.H. Chan School of Public Health.

Kukreja has received many professional honors, including the Pharmacia/Upjohn Trauma Research Competition Award, John A. Mannick Research Award and an excellence in teaching award from Harvard Medical School.

Education

2018 - Diversity, Equity, and Inclusion Champion Training, University of California
M.D., 1994 - School of Medicine, University of California Los Angeles
Postdoctoral Studies, - Graduate Division, University of California, San Francisco

Selected Publications

  1. Santos J, Wang P, Shemesh A, Liu F, Tsao T, Aguilar OA, Cleary SJ, Singer JP, Gao Y, Hays SR, Golden J, Leard LE, Kleinhenz ME, Kolaitis NA, Shah RJ, Venado A, Kukreja J, Weigt SS, Belperio JA, Lanier LL, Looney MR, Greenland JR, Calabrese DR. CCR5 drives NK cell-associated airway damage in pulmonary ischemia-reperfusion injury. JCI Insight. 2023 Oct 03.  View on PubMed
  2. Greenland JR, Guo R, Lee S, Tran L, Kapse B, Kukreja J, Hays SR, Golden JA, Calabrese DR, Singer JP, Wolters PJ. Short Airway Telomeres are Associated with Primary Graft Dysfunction and Chronic Lung Allograft Dysfunction. J Heart Lung Transplant. 2023 Aug 28.  View on PubMed
  3. Santos J, Hays SR, Golden JA, Calabrese DR, Kolaitis N, Kleinhenz ME, Shah R, Estrada AV, Leard LE, Kukreja J, Singer JP, Greenland JR. Decreased Lymphocytic Bronchitis Severity in the Era of Azithromycin Prophylaxis. Transplant Direct. 2023 Sep; 9(9):e1495.  View on PubMed
  4. Bromberger B, Brzezinski M, Kukreja J. Prone Positioning after Lung Transplantation Remains Prone to Debate. Ann Thorac Surg. 2023 Jul 19.  View on PubMed
  5. Luu HY, Santos J, Isaza E, Brzezinski M, Kukreja J. Management of primary graft dysfunction after lung transplantation with extracorporeal life support: an evidence-based review. J Thorac Dis. 2023 Jul 31; 15(7):4090-4100.  View on PubMed
  6. Nguyen A, Chen J, Isaza E, Panchal N, Deiter F, Hoover J, Trinh B, Hays SR, Golden JA, Singer JP, Brzezinski M, Greenland JR, Kukreja J. Biofire pneumonia panel in lung donors: faster detection but limited pathogens. Transpl Infect Dis. 2023 Aug; 25(4):e14091.  View on PubMed
  7. Singer JP, Gao Y, Huang CY, Kordahl RC, Sriram A, Hays SR, Kukreja J, Venado A, Calabrese DR, Greenland JR. The Association Between Frailty and Chronic Lung Allograft Dysfunction After Lung Transplantation. Transplantation. 2023 10 01; 107(10):2255-2261.  View on PubMed
  8. Mladinov D, Isaza E, Gosling AF, Clark AL, Kukreja J, Brzezinski M. Perioperative Fluid Management. Anesthesiol Clin. 2023 Sep; 41(3):613-629.  View on PubMed
  9. Bromberger B, Calabrese DR, Brzezinski M, Kukreja J. Regadenoson is all the RAGE: Targeting the inflammatory cascade in Primary Graft Dysfunction. Ann Thorac Surg. 2023 Apr 14.  View on PubMed
  10. Bromberger B, Brzezinski M, Kukreja J. Lung preservation: from perfusion to temperature. Curr Opin Organ Transplant. 2023 06 01; 28(3):168-173.  View on PubMed
  11. Singer JP, Christie JD, Diamond JM, Anderson MA, Benvenuto LA, Gao Y, Arcasoy SM, Lederer DJ, Calabrese D, Wang P, Hays SR, Kukreja J, Venado A, Kolaitis NA, Leard LE, Shah RJ, Kleinhenz ME, Golden J, Betancourt L, Oyster M, Zaleski D, Adler J, Kalman L, Balar P, Patel S, Medikonda N, Koons B, Tevald M, Covinsky KE, Greenland JR, Katz PK. Development of the Lung Transplant Frailty Scale (LT-FS). J Heart Lung Transplant. 2023 Jul; 42(7):892-904.  View on PubMed
  12. Cypel M, Hötzenecker K, Campo-Cañaveral de la Cruz J, Kukreja J, Suarez E, Smith M, Bush EL. Lungs Preserved on Ice or in a Refrigerator? Prolonged Static Lung Storage at 10 °C. Ann Thorac Surg. 2023 05; 115(5):1095-1097.  View on PubMed
  13. Singer JP, Calfee CS, Delucchi K, Diamond JM, Anderson MA, Benvenuto LA, Gao Y, Wang P, Arcasoy SM, Lederer DJ, Hays SR, Kukreja J, Venado A, Kolaitis NA, Leard LE, Shah RJ, Kleinhenz ME, Golden J, Betancourt L, Oyster M, Brown M, Zaleski D, Medikonda N, Kalman L, Balar P, Patel S, Calabrese DR, Greenland JR, Christie JD. Subphenotypes of frailty in lung transplant candidates. Am J Transplant. 2023 04; 23(4):531-539.  View on PubMed
  14. Odisho AY, Liu AW, Maiorano AR, Bigazzi MOA, Medina E, Leard LE, Shah R, Venado A, Perez A, Golden J, Kleinhenz ME, Kolaitis NA, Maheshwari J, Trinh BN, Kukreja J, Greenland J, Calabrese D, Neinstein AB, Singer JP, Hays SR. Design and implementation of a digital health home spirometry intervention for remote monitoring of lung transplant function. J Heart Lung Transplant. 2023 06; 42(6):828-837.  View on PubMed
  15. Kolaitis NA, Chen H, Calabrese DR, Kumar K, Obata J, Bach C, Golden JA, Simon MA, Kukreja J, Hays SR, Leard LE, Singer JP, De Marco T. The Lung Allocation Score Remains Inequitable for Patients with Pulmonary Arterial Hypertension, Even after the 2015 Revision. Am J Respir Crit Care Med. 2023 02 01; 207(3):300-311.  View on PubMed
  16. Sawinski D, Lai JC, Pinney S, Gray AL, Jackson AM, Stewart D, Levine DJ, Locke JE, Pomposelli JJ, Hartwig MG, Hall SA, Dadhania DM, Cogswell R, Perez RV, Schold JD, Turgeon NA, Kobashigawa J, Kukreja J, Magee JC, Friedewald J, Gill JS, Loor G, Heimbach JK, Verna EC, Walsh MN, Terrault N, Testa G, Diamond JM, Reese PP, Brown K, Orloff S, Farr MA, Olthoff KM, Siegler M, Ascher N, Feng S, Kaplan B, Pomfret E. Addressing sex-based disparities in solid organ transplantation in the United States - a conference report. Am J Transplant. 2023 03; 23(3):316-325.  View on PubMed
  17. Calabrese DR, Chong T, Singer JP, Rajalingam R, Hays SR, Kukreja J, Leard L, Golden JA, Lanier LL, Greenland JR. CD16+ natural killer cells in bronchoalveolar lavage are associated with antibody-mediated rejection and chronic lung allograft dysfunction. Am J Transplant. 2023 01; 23(1):37-44.  View on PubMed
  18. Macrae TA, Lazo J, Viduya J, Florez R, Dewey K, Gao Y, Singer JP, Hays SR, Golden JA, Kukreja J, Greenland JR, Calabrese DR. Frailty and genetic risk predict fracture after lung transplantation. Am J Transplant. 2023 02; 23(2):214-222.  View on PubMed
  19. DesJardin JT, Svetlichnaya Y, Kolaitis NA, Hays SR, Kukreja J, Schiller NB, Zier LS, Singer JP, De Marco T. Echocardiographic estimation of pulmonary vascular resistance in advanced lung disease. Pulm Circ. 2023 Jan; 13(1):e12183.  View on PubMed
  20. Calabrese DR, Tsao T, Magnen M, Valet C, Gao Y, Mallavia B, Tian JJ, Aminian EA, Wang KM, Shemesh A, Punzalan EB, Sarma A, Calfee CS, Christenson SA, Langelier CR, Hays SR, Golden JA, Leard LE, Kleinhenz ME, Kolaitis NA, Shah R, Venado A, Lanier LL, Greenland JR, Sayah DM, Ardehali A, Kukreja J, Weigt SS, Belperio JA, Singer JP, Looney MR. NKG2D receptor activation drives primary graft dysfunction severity and poor lung transplantation outcomes. JCI Insight. 2022 12 22; 7(24).  View on PubMed

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