Research Summary

Sharmila Majumdar, PhD, is a UCSF Professor and the Vice Chair of Research in the Department of Radiology and Biomedical Imaging and Professor in the Departments of Bioengineering and Therapeutic Sciences, Orthopedic Surgery at UCSF and Bioengineering at UC Berkeley. She is Director of the Musculoskeletal Research Interest Group at UCSF, an interdisciplinary group consisting of faculty, post-doctoral scholars and students. She obtained her PhD degree in Engineering and Applied Science from Yale University in 1987, where she stayed as a post-doctoral researcher and Assistant Professor until 1989, when she joined UCSF.

Her research work on imaging, particularly magnetic resonance and micro computed tomography, and development of image processing and analysis tools, has been focused in the areas of osteoporosis, osteo-arthritis and lower back pain. Her research, which is supported by grants from the NIH and corporate entities, and is diverse ranging from technical development to clinical trials. She currently heads an NIH Center of Research Translation focused on Osteoarthritis and Imaging, a joint effort between UCSF and UC Davis.

Dr. Majumdar was selected as a fellow of the American Institute of Medical and Biological Engineers in 2004 and a fellow of the International Society of Magnetic Resonance in Medicine in 2008. In 2007 she was awarded the “Excellence in Direct Teaching and/or Excellence in Mentoring and Advising Award” by the UCSF Haile T. Debas Academy of Medical Educators.

She has published extensively in the Journal of Bone Mineral Research, Magnetic Resonance in Medicine, and other highly regarded journals. She also serves as a reviewer and is on the editorial board of scientific journals, and is a recognized expert in the area of imaging.

Research Funding

  • September 26, 2019 - July 31, 2024 - Technology Research Site for Advanced, Faster Quantitative Imaging for BACPAC, Principal Investigator. Sponsor: NIH/NIAMS, Sponsor Award ID: UH3AR076724
  • April 1, 2018 - July 31, 2021 - Deep Learning for Characterizing Knee Joint Degeneration Predicting Progression of Osteoarthritis and Total Knee Replacement, Principal Investigator. Sponsor: NIH/NIAMS, Sponsor Award ID: R33AR073552
  • July 14, 2016 - April 30, 2021 - Evaluating Disease Progression in Hip Osteoarthritis, Principal Investigator. Sponsor: NIH/NIAMS, Sponsor Award ID: R01AR069006
  • September 26, 2019 - August 31, 2020 - Technology Research Site for Advanced, Faster Quantitative Imaging for BACPAC, Principal Investigator. Sponsor: NIH/NIAMS, Sponsor Award ID: UH2AR076724

Education

St. Stephens College, University of Delhi, India, B.S., 1983, Physics
Yale University, Connecticut, USA, M.S., 1984, Eng. & Applied Physics
Yale University, Connecticut, USA, Ph.D., 1987, Eng. & Applied Physics
Yale University, Connecticut, USA, Postdoctoral, 1988, Radiology

Honors & Awards

  • 2002
    Celebrating Woman Faculty, Award and Recognition, Chancellor and Deans of UCSF
  • 2004
    Fellow of the American Institute of Medical and Biological Engineers (AIMBE)
  • 2008
    Fellow of the International Society of Magnetic Resonance in Medicine (ISMRM)
  • 2016
    Gold Medal of International Society of Magnetic Resonance in Medicine (ISMRM)

Selected Publications

  1. Flores M, Dayan I, Roth H, Zhong A, Harouni A, Gentili A, Abidin A, Liu A, Costa A, Wood B, Tsai CS, Wang CH, Hsu CN, Lee CK, Ruan C, Xu D, Wu D, Huang E, Kitamura F, Lacey G, Corradi GCA, Shin HH, Obinata H, Ren H, Crane J, Tetreault J, Guan J, Garrett J, Park JG, Dreyer K, Juluru K, Kersten K, Rockenbach MABC, Linguraru M, Haider M, AbdelMaseeh M, Rieke N, Damasceno P, Silva PMCE, Wang P, Xu S, Kawano S, Sriswa S, Park SY, Grist T, Buch V, Jantarabenjakul W, Wang W, Tak WY, Li X, Lin X, Kwon F, Gilbert F, Kaggie J, Li Q, Quraini A, Feng A, Priest A, Turkbey B, Glicksberg B, Bizzo B, Kim BS, Tor-Diez C, Lee CC, Hsu CJ, Lin C, Lai CL, Hess C, Compas C, Bhatia D, Oermann E, Leibovitz E, Sasaki H, Mori H, Yang I, Sohn JH, Murthy KNK, Fu LC, de Mendonça MRF, Fralick M, Kang MK, Adil M, Gangai N, Vateekul P, Elnajjar P, Hickman S, Majumdar S, McLeod S, Reed S, Graf S, Harmon S, Kodama T, Puthanakit T, Mazzulli T, Lavor VL, Rakvongthai Y, Lee YR, Wen Y Federated Learning used for predicting outcomes in SARS-COV-2 patients.  View on PubMed
  2. Tibrewala R, Pedoia V, Lee J, Kinnunen C, Popovic T, Zhang AL, Link TM, Souza RB, Majumdar S Automatic Hip Abductor Muscle Fat Fraction Estimation and Association with Early OA Cartilage Degeneration Biomarkers.  View on PubMed
  3. Gao KT, Pedoia V, Young KA, Kogan F, Koff MF, Gold GE, Potter HG, Majumdar S Multiparametric MRI characterization of knee articular cartilage and subchondral bone shape in collegiate basketball players.  View on PubMed
  4. Iriondo C, Liu F, Calivà F, Kamat S, Majumdar S, Pedoia V Towards Understanding Mechanistic Subgroups of Osteoarthritis: 8 Year Cartilage Thickness Trajectory Analysis.  View on PubMed
  5. Liao TC, Jergas H, Tibrewala R, Bahroos E, Link TM, Majumdar S, Souza RB, Pedoia V Longitudinal analysis of the contribution of 3D patella and trochlear bone shape on patellofemoral joint osteoarthritic features.  View on PubMed
  6. Namiri NK, Flament I, Astuto B, Shah R, Tibrewala R, Caliva F, Link TM, Pedoia V, Majumdar S Deep Learning for Hierarchical Severity Staging of Anterior Cruciate Ligament Injuries from MRI.  View on PubMed
  7. Razmjoo A, Caliva F, Lee J, Liu F, Joseph GB, Link TM, Majumdar S, Pedoia V T2 analysis of the entire osteoarthritis initiative dataset.  View on PubMed
  8. Liao TC, Martinez AGM, Pedoia V, Ma BC, Li X, Link TM, Majumdar S, Souza RB Patellar Malalignment Is Associated With Patellofemoral Lesions and Cartilage Relaxation Times After Hamstring Autograft Anterior Cruciate Ligament Reconstruction.  View on PubMed
  9. Shaw C, Warwick H, Nguyen KH, Link TM, Majumdar S, Souza RB, Vail TP, Zhang AL Correlation of hip capsule morphology with patient symptoms from femoroacetabular impingement.  View on PubMed
  10. Popovic T, Samaan MA, Link TM, Majumdar S, Souza RB Patients with Symptomatic Hip Osteoarthritis Have Altered Kinematics during Stair Ambulation.  View on PubMed
  11. Kumar D, Link TM, Jafarzadeh SR, LaValley MP, Majumdar S, Souza RB Quadriceps adiposity is associated with increase in lesions of the knee cartilage, meniscus, or bone marrow over 3-years.  View on PubMed
  12. Tibrewala R, Ozhinsky E, Shah R, Flament I, Crossley K, Srinivasan R, Souza R, Link TM, Pedoia V, Majumdar S Computer-Aided Detection AI Reduces Interreader Variability in Grading Hip Abnormalities With MRI.  View on PubMed
  13. Tolpadi AA, Lee JJ, Pedoia V, Majumdar S Deep Learning Predicts Total Knee Replacement from Magnetic Resonance Images.  View on PubMed
  14. Morales Martinez A, Caliva F, Flament I, Liu F, Lee J, Cao P, Shah R, Majumdar S, Pedoia V Learning osteoarthritis imaging biomarkers from bone surface spherical encoding.  View on PubMed
  15. Tibrewala R, Pedoia V, Bucknor M, Majumdar S Principal Component Analysis of Simultaneous PET-MRI Reveals Patterns of Bone-Cartilage Interactions in Osteoarthritis.  View on PubMed
  16. Iriondo C, Pedoia V, Majumdar S Lumbar intervertebral disc characterization through quantitative MRI analysis: An automatic voxel-based relaxometry approach.  View on PubMed
  17. Lansdown DA, Xiao W, Zhang AL, Allen CR, Feeley BT, Li X, Majumdar S, Ma CB Quantitative imaging of anterior cruciate ligament (ACL) graft demonstrates longitudinal compositional changes and relationships with clinical outcomes at 2 years after ACL reconstruction.  View on PubMed
  18. Samaan MA, Grace T, Zhang AL, Majumdar S, Souza RB Short term outcomes of hip arthroscopy on hip joint mechanics and cartilage health in patients with femoroacetabular impingement syndrome.  View on PubMed
  19. Chaudhari AS, Kogan F, Pedoia V, Majumdar S, Gold GE, Hargreaves BA Rapid Knee MRI Acquisition and Analysis Techniques for Imaging Osteoarthritis.  View on PubMed
  20. Foreman SC, Zhang AL, Neumann J, von Schacky CE, Souza RB, Majumdar S, Link TM Postoperative MRI Findings and Associated Pain Changes After Arthroscopic Surgery for Femoroacetabular Impingement.  View on PubMed

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