Research Summary

Dr. Rita Mukhtar specializes in breast surgery and general surgery for urgent conditions. For her patients with breast cancer, she offers expertise in total skin-sparing mastectomies, breast conservation, wire localization surgery (used to show the location of tissue requiring biopsy) and sentinel lymph node biopsy (used to see if cancer has spread).

Dr. Mukhtar's research program focuses on invasive lobular carcinoma, the second most common type of breast cancer. This work is funded by the American Cancer Society and the National Cancer Institute. She teaches medical students and residents, and serves as an Associate Program Director for the UCSF General Surgery Residency.

Education

UC Berkeley, AB, 12/2000, Molecular and Cell Biology
UC San Francisco, MD, 05/2006
UC San Francisco, Postdoctoral Fellow, 06/2011, Advanced Training in Clinical Research
UC San Francisco, Resident, 06/2013, General Surgery
UC San Francisco, Fellow, 06/2014, Breast Surgical Oncology

Honors & Awards

  • 2003
    Storer Scholarship, UCSF School of Medicine
  • 2005
    Student Research Award, Association for Academic Surgery
  • 2006
    Steinhart Scholarship, UCSF School of Medicine
  • 2007
    Dr Galante Scholarship Award, UCSF Department of Surgery
  • 2009
    Resident Research Scholarship, UCSF CTSI
  • 2013
    Teaching Award for Cherished Housestaff, UCSF School of Medicine
  • 2013
    Lawrence Way Critical Thinking Award, UCSF Department of Surgery

Selected Publications

  1. Rita A. Mukhtar, Katrina Dimitroff, Christina Yau, A. Jo Chien, Eileen P. Connolly, Marissa Howard-McNatt, Roshni Rao, Velle Ladores, Mehra Golshan, Candice A. Sauder, Kamran Ahmed, Rachael Lancaster, Jana Fox, Lily Gutnik, M. Catherine Lee, Julia Tchou, Nicolas Prionas, Cletus A. Arciero, Chantal Reyna, Henry Kuerer, Kayla Switalla, Neil Taunk, Todd M. Tuttle, Meena S. Moran, Lauren M. Postlewait, Jane Perlmutter, Angela DeMichele, Douglas Yee, Nola Hylton, W. Fraser Symmans, Hope S. Rugo, Rebecca Shatsky, Claudine Isaacs, Laura J. Esserman, Laura van ‘t Veer, Judy C. Boughey ASO Visual Abstract: Impact of Neoadjuvant Chemotherapy on Surgical Outcomes and Conversion to Node-Negativity in Invasive Lobular Breast Cancer: Analysis of Molecularly High-Risk Tumors by Histologic Subtype on the I-SPY2 Clinical Trial.  View on PubMed
  2. Van Hassel J, Dimitroff K, Yau C, Mukhtar R, Boughey JC, Ladores V, Howard-McNatt MM, Jaskowiak N, Perlmutter J, DeMichele A, Yee D, Hylton N, Symmans WF, Veer LV, Rugo H, Esserman LJ, Shatsky R, Isaacs C, Kuerer H, Wallace AM, Prionas N, Tseng J, Reyna CR, Taunk N, Kesmodel S, Lee MC, Fox J, Piltin MA, Tchou J, Arciero CA, Postlewait LM, Sauder C, Rao R Impact of Time to Surgery Post Neoadjuvant Chemotherapy on Breast Cancer Outcomes: A Retrospective Study of Patients Enrolled in the I-SPY 2 Clinical Trial.  View on PubMed
  3. M. Kaur, K. Dimitroff, J. C. Boughey, L. J. Esserman, C. Yau, J. Tchou, A. Quirarte, M. C. Lee, M. M. Howard-McNatt, K. Switalla, H. Kuerer, C. Sauder, L. M. Postlewait, C. Arciero, Roshni Rao, A. Wallace, C. Reyna, K. Ahmed, L. Gutnik, N. Taunk, J. Perlmutter, A. DeMichele, D. Yee, N. M. Hylton, F. Symmans, H. S. Rugo, R. A. Shatsky, C. Isaacs, S. Rudra, P. Pohlmann, C. Ewing, J. Wong, M. Alvarado, N. Jaskowiak, N. Prionas, M. Golshan, M. A. Piltin, O. I. Olopade, R. A. Mukhtar ASO Visual Abstract: Disparities in the Surgical Management of the Axilla by Self-Identified Race in the Multicenter Neoadjuvant I-SPY2 Trial.  View on PubMed
  4. Corso G, Shen S, Criscitiello C, Mukhtar R, Gamble L, Rocco EG, Pesapane F, Nicosia L, Jhaveri K, Salimbeni BT, Massari G, Meduri E, De Scalzi AM, Concardi A, Magnoni F, Mamtani A, Pareja F, Leonardi MC, Sacchini V, Bogani G, Vecchia C, Presti D, Colleoni MA, Veronesi P, Robson ME Invasive lobular carcinoma: Strategies and perspectives from the lobular breast cancer research group.  View on PubMed
  5. Kaur M, Boughey JC, Mukhtar RA ASO Author Reflections: Equity in the Surgical Management of the Axilla.  View on PubMed
  6. Anna Vertido, Tesia McKenzie, Alisha Othieno, Astrid Quirarte, Mandeep Kaur, Mary Kathryn Abel, Maggie Chung, Amie Y. Lee, Rita A. Mukhtar ASO Visual Abstract: Accuracy of Breast MRI for Surgical Planning After Neoadjuvant Therapy for Patients with Invasive Lobular Carcinoma.  View on PubMed
  7. Mukhtar RA, Dimitroff K, Yau C, Chien AJ, Connolly EP, Howard-McNatt M, Rao R, Ladores V, Golshan M, Sauder CA, Ahmed K, Lancaster R, Fox J, Gutnik L, Lee MC, Tchou J, Prionas N, Arciero CA, Reyna C, Kuerer H, Switalla K, Taunk N, Tuttle TM, Moran MS, Postlewait LM, Perlmutter J, DeMichele A, Yee D, Hylton N, Symmans WF, Rugo HS, Shatsky R, Isaacs C, Esserman LJ, Van't Veer L, Boughey JC Impact of Neoadjuvant Chemotherapy on Surgical Outcomes and Conversion to Node-Negativity in Invasive Lobular Breast Cancer: Analysis of Molecularly High-Risk Tumors by Histologic Subtype on the I-SPY2 Clinical Trial.  View on PubMed
  8. Kaur M, Dimitroff K, Boughey JC, Esserman LJ, Yau C, Tchou J, Quirarte A, Lee MC, Howard-McNatt MM, Switalla K, Kuerer H, Sauder C, Postlewait LM, Arciero C, Rao R, Wallace A, Reyna C, Ahmed K, Gutnik L, Taunk N, Perlmutter J, DeMichele A, Yee D, Hylton NM, Symmans WF, Rugo HS, Shatsky RA, Isaacs C, Rudra S, Pohlmann P, Ewing C, Wong J, Alvarado M, Jaskowiak N, Prionas N, Golshan M, Piltin MA, Olopade OI, Mukhtar RA Disparities in the Surgical Management of the Axilla by Self-Identified Race in the Multicenter Neoadjuvant I-SPY2 Trial.  View on PubMed
  9. Van Baelen K, Sawyer E, Van Cauwenberge J, Aftimos P, Covington MF, Maetens M, Zels G, Brisken C, Djerroudi L, Dresen R, Fitzpatrick A, Flaherty RL, Floris G, Freeney S, Hanker AB, Honey D, Isacke CM, Jankowitz RC, Jeselsohn R, Koorman T, Kuhl C, Linn S, Lord CJ, Malhaire C, Mouabbi J, Mukhtar R, Nader-Marta G, Natrajan R, Neven P, Oesterreich S, Sandoval JL, Schnitt SJ, Senkus E, Turner C, Vandecaveye V, Wildiers H, Vincent-Salomon A, Derksen PWB, Desmedt C Clinical challenges and proposed solutions for patients with invasive lobular breast cancer.  View on PubMed
  10. Vertido A, Mukhtar RA ASO Author Reflections: Accuracy of MRI in Invasive Lobular Carcinoma after Neoadjuvant Therapy: Impact of Non-mass Enhancement.  View on PubMed
  11. Vertido A, McKenzie T, Othieno A, Quirarte A, Kaur M, Abel MK, Chung M, Lee AY, Mukhtar RA Accuracy of Breast MRI for Surgical Planning After Neoadjuvant Therapy for Patients with Invasive Lobular Carcinoma.  View on PubMed
  12. Kaur M, Quirarte A, Shui AM, Vertido A, Clelland E, Rothschild H, Esserman LJ, Ewing C, Mukhtar RA Socioeconomic status impacts tumor biology, treatment, and outcomes in over 200,000 patients with invasive lobular carcinoma of the breast: an analysis of the National Cancer Database.  View on PubMed
  13. Leon-Ferre RA, Dimitroff K, Yau C, Giridhar KV, Mukhtar R, Hirst G, Hylton N, Perlmutter J, DeMichele A, Yee D, van 't Veer L, Rugo H, Symmans WF, Goetz MP, Esserman L, Boughey JC Combined prognostic impact of initial clinical stage and residual cancer burden after neoadjuvant systemic therapy in triple-negative and HER2-positive breast cancer: an analysis of the I-SPY2 randomized clinical trial.  View on PubMed
  14. Switalla KM, Mukhtar RA ASO Author Reflections: Reassessing Positive Margins in Breast-Conserving Surgery: The Role of Histology and Oncoplastic Surgery.  View on PubMed
  15. Flanagan MR, van den Bruele AMB, Downs-Canner SM, Thomas SM, Gallagher KK, Jakub JW, Tevis SEA, Verdial FC, Zhang JQ, Elmore LC, Mukhtar RA, Brennan M, Lillie M, Gibson TC, Verosky A, Plichta JK, Rosenberger LH ASO Visual Abstract: A Multi-institutional Analysis of Contralateral Axillary Metastases-Advanced Local-Regional Disease Divergent from Stage IV Breast Cancer.  View on PubMed
  16. Chandler Scott Cortina, Ruta Brazauskas, Meghan Rose Flanagan, Kathie-Ann P. Joseph, Rita Mukhtar, Olga Kantor, Kristen M. Rezak, Laura Horst Rosenberger, Sumanas Jordan, Rachel Jimenez, Katherine A. Kopkash, Tasha Hughes, Meeghan A. Lautner, Emily L. Siegel, Zahraa Alhilli, Michael Ryan Cassidy, Rachel L. McCaffrey, Marie Catherine Lee, Anna Weiss, Melinda Stolley Breast cancer diagnosis, management, and outcomes in transgender, nonbinary, and gender-diverse individuals: A multicenter cohort.  View on PubMed
  17. Silver Alkhafaji, Mark Jesus M Magbanua, Laura van t Veer, Karthik Giridhar, Matthew P. Goetz, Rita Mukhtar, Christos Vaklavas, Anthony D. Elias, Mei Wei, Gillian L. Hirst, Hope S. Rugo, Laura Ann Huppert, W. Fraser Fraser Symmans, Alexander D. Borowsky, Lamorna Brown Swigart, Natsuko Onishi, Douglas Yee, Nola Hylton, Laura Esserman, Jo Chien Circulating tumor DNA (ctDNA) in patients with stage 2/3 HR+HER2-negative breast cancer (BC) treated with neoadjuvant endocrine therapy (NET) in the I-SPY2 endocrine optimization pilot (EOP) trial.  View on PubMed
  18. Mei Wei, Anthony D. Elias, Karthik Giridhar, Matthew P. Goetz, Rita Mukhtar, Christos Vaklavas, Laura van t Veer, Silver Alkhafaji, Gillian L. Hirst, Hope S. Rugo, Nan Chen, W. Fraser Fraser Symmans, Alexander D. Borowsky, Lamorna Brown Swigart, Natsuko Onishi, Douglas Yee, Nola Hylton, Laura Esserman, Jo Chien I-SPY2 endocrine optimization pilot (EOP): Neoadjuvant lasofoxifene (Laso) in molecularly selected patients with hormone receptor positive (HR+)/HER2 negative (HER2-) stage 2/3 breast cancer (BC).  View on PubMed
  19. Astrid Quirarte, Anna Lannhi Vertido, Sophia Zamudio-Haas, Jo Chien, Rita Mukhtar Patient experiences of diagnosis and treatment of invasive lobular carcinoma: A qualitative study from a prospective registry.  View on PubMed
  20. Thomas O'Keefe, Christina Yau, Sophie Lin, Nicolas Prionas, Gillian L. Hirst, Rita Mukhtar, Anne M. Wallace, Michael Alvarado, Laura Esserman Reframing hormone-positive DCIS management: Effects of adjuvant therapies and surgical extent on any invasive recurrence.  View on PubMed

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