Research Funding

  • August 15, 2017 - July 31, 2022 - Research training in HIV-related transfusion medicine and hematology in South Africa , Principal Investigator . Sponsor: NIH, Sponsor Award ID: D43TW010345
  • April 1, 2013 - March 31, 2017 - Recipient Epidemiology and Donor Evaluation Study III (REDS-III) Internat'l Site , Principal Investigator . Sponsor: NIH, Sponsor Award ID: 268201100009I-2-26800002-1
  • March 15, 2013 - March 14, 2017 - Recipient Epidemiology and Donor Evaluation Study III (REDS-III) Domestic Hub , Principal Investigator . Sponsor: NIH, Sponsor Award ID: 268201100005I-2-26800002-1
  • January 5, 2004 - May 31, 2016 - Health Outcomes in Blood Donors and Recipients , Principal Investigator . Sponsor: NIH, Sponsor Award ID: K24HL075036

Education

Massachusetts Institute of Technology, B.S., 1974, Marine Biology
Stanford University, Stanford, CA, M.D., 1980, Medicine
University of California, Berkeley, CA, M.P.H., 1981, Epidemiology

Honors & Awards

  • 1970
    Westinghouse Scholarship
  • 1980-81
    University of California Graduate Scholarship
  • 1984
    Chateaubriand prize of the French Government
  • 1984
    International Agency for Cancer Research Fellowship (declined)
  • 1988
    FDA Commissioners Special Citation
  • 1989-92
    Charles E. Culpeper Scholarship
  • 1995-96
    Fulbright Scholarship, France
  • 1995-96
    NIH Fogarty Senior International Fellowship
  • 2003
    President, International Retrovirology Association

Selected Publications

  1. Miranda C, Utsch-Gonçalves D, Piassi FCC, Loureiro P, Gomes I, Ribeiro MA, de Almeida-Neto C, Blatyta P, Amorim L, Garcia Mateos SO, Murphy EL, Custer B, Carneiro-Proietti ABF, Sabino EC. Prevalence and Risk Factors for Human T-Cell Lymphotropic Virus (HTLV) in Blood Donors in Brazil-A 10-Year Study (2007-2016). Front Med (Lausanne). 2022; 9:844265.  View on PubMed
  2. Kim D, Myllymäki M, Kankainen M, Jarvinen T, Park G, Bruhn R, Murphy EL, Mustjoki S. Somatic STAT3 mutations in CD8+ T cells of healthy blood donors carrying human T-cell leukemia virus type 2. Haematologica. 2022 02 01; 107(2):550-554.  View on PubMed
  3. Valencia A, Vergara C, Thio CL, Vince N, Douillard V, Grifoni A, Cox AL, Johnson EO, Kral AH, Goedert JJ, Mangia A, Piazzolla V, Mehta SH, Kirk GD, Kim AY, Lauer GM, Chung RT, Price JC, Khakoo SI, Alric L, Cramp ME, Donfield SM, Edlin BR, Busch MP, Alexander G, Rosen HR, Murphy EL, Wojcik GL, Carrington M, Gourraud PA, Sette A, Thomas DL, Duggal P. Trans-ancestral fine-mapping of MHC reveals key amino acids associated with spontaneous clearance of hepatitis C in HLA-DQβ1. Am J Hum Genet. 2022 02 03; 109(2):299-310.  View on PubMed
  4. Marqué L, Liehl P, De Boer J, Pottel H, Murphy EL, Bruhn R, Stone M, Kaidarova Z, Lee TH, Busch M, Zrein M. A novel high performing multiplex immunoassay Multi-HTLV for serological confirmation and typing of HTLV infections. PLoS Negl Trop Dis. 2021 11; 15(11):e0009925.  View on PubMed
  5. Rapodile T, Mitchel J, Swanevelder R, Murphy EL, van den Berg K. Re-engineering the medical assessment of blood donors in South Africa: The balance between supply and safety. Transfusion. 2021 12; 61(12):3361-3371.  View on PubMed
  6. van den Berg K, Vermeulen M, Louw VJ, Murphy EL, Maartens G. Undisclosed HIV status and antiretroviral therapy use among South African blood donors. Transfusion. 2021 08; 61(8):2392-2400.  View on PubMed
  7. Vermeulen M, Swanevelder R, Van Zyl G, Lelie N, Murphy EL. An assessment of hepatitis B virus prevalence in South African young blood donors born after the implementation of the infant hepatitis B virus immunization program: Implications for transfusion safety. Transfusion. 2021 09; 61(9):2688-2700.  View on PubMed
  8. Vergara C, Valencia A, Thio CL, Goedert JJ, Mangia A, Piazzolla V, Johnson E, Kral AH, O'Brien TR, Mehta SH, Kirk GD, Kim AY, Lauer GM, Chung RT, Cox AL, Peters MG, Khakoo SI, Alric L, Cramp ME, Donfield SM, Edlin BR, Busch MP, Alexander G, Rosen HR, Murphy EL, Wojcik GL, Taub MA, Thomas DL, Duggal P. A Multiancestry Sex-Stratified Genome-Wide Association Study of Spontaneous Clearance of Hepatitis C Virus. J Infect Dis. 2021 06 15; 223(12):2090-2098.  View on PubMed
  9. Samje M, Fondoh VN, Nguefack-Tsague G, Kamalieuk LKJ, Mbanya D, Murphy EL, Tagny CT. Trends in serological markers of transfusion transmissible infections in blood donations at the Bamenda Hospital-based Blood Service, Cameroon. Transfus Clin Biol. 2021 Aug; 28(3):228-233.  View on PubMed
  10. Clements DM, Crumley B, Chew GM, Davis E, Bruhn R, Murphy EL, Ndhlovu LC, Jain P. Phenotypic and Functional Analyses Guiding Combination Immune Checkpoint Immunotherapeutic Strategies in HTLV-1 Infection. Front Immunol. 2021; 12:608890.  View on PubMed
  11. Vergara C, Duggal P, Thio CL, Valencia A, O'Brien TR, Latanich R, Timp W, Johnson EO, Kral AH, Mangia A, Goedert JJ, Piazzola V, Mehta SH, Kirk GD, Peters MG, Donfield SM, Edlin BR, Busch MP, Alexander G, Murphy EL, Kim AY, Lauer GM, Chung RT, Cramp ME, Cox AL, Khakoo SI, Rosen HR, Alric L, Wheelan SJ, Wojcik GL, Thomas DL, Taub MA. Correction: Multi-ancestry fine mapping of interferon lambda and the outcome of acute hepatitis C virus infection. Genes Immun. 2020 Dec; 21(6-8):420.  View on PubMed
  12. Vergara C, Duggal P, Thio CL, Valencia A, O'Brien TR, Latanich R, Timp W, Johnson EO, Kral AH, Mangia A, Goedert JJ, Piazzola V, Mehta SH, Kirk GD, Peters MG, Donfield SM, Edlin BR, Busch MP, Alexander G, Murphy EL, Kim AY, Lauer GM, Chung RT, Cramp ME, Cox AL, Khakoo SI, Rosen HR, Alric L, Wheelan SJ, Wojcik GL, Thomas DL, Taub MA. Multi-ancestry fine mapping of interferon lambda and the outcome of acute hepatitis C virus infection. Genes Immun. 2020 11; 21(5):348-359.  View on PubMed
  13. Roubinian NH, Chowdhury D, Hendrickson JE, Triulzi DJ, Gottschall JL, Looney MR, Matthay MA, Kor DJ, Brambilla D, Kleinman SH, Murphy EL, NHLBI Recipient Epidemiology and Donor Evaluation Study-III (REDS-III). NT-proBNP levels in the identification and classification of pulmonary transfusion reactions. Transfusion. 2020 11; 60(11):2548-2556.  View on PubMed
  14. Vermeulen M, Chowdhury D, Swanevelder R, Grebe E, Brambilla D, Jentsch U, Busch M, Van Zyl G, Murphy EL, REDS-III International Program South Africa. HIV incidence in South African blood donors from 2012 to 2016: a comparison of estimation methods. Vox Sang. 2021 Jan; 116(1):71-80.  View on PubMed
  15. Estrada FGMD, Oliveira CDL, Sabino EC, Custer B, Gonçalez TT, Murphy EL, Teles D, Mendrone-Junior A, Witkin SS, de Almeida-Neto C. Are different motivations and social capital score associated with return behaviour among Brazilian voluntary non-remunerated blood donors? Transfus Med. 2020 Aug; 30(4):255-262.  View on PubMed
  16. Tagny CT, Bissim M, Djeumen R, Ngo Sack F, Angandji P, Ndoumba A, Kouanfack C, Eno L, Mbanya D, Murphy EL, Laperche S. The use of the GeeniusTM HIV-1/2 Rapid confirmatory test for the enrolment of patients and blood donors in the WHO Universal Test and Treat Strategy in Cameroon, Africa. Vox Sang. 2020 Nov; 115(8):686-694.  View on PubMed
  17. Bruhn R, Karafin MS, Hilton JF, Kaidarova Z, Spencer BR, Qu L, Snyder EL, Olin R, Murphy EL, St Lezin E, NHLBI Recipient Epidemiology and Donor Evaluation Study (REDS)-III Program. Early and sustained improvement in fatigue-related quality of life following red blood cell transfusion in outpatients. Qual Life Res. 2020 Oct; 29(10):2737-2744.  View on PubMed
  18. Bloch EM, Hull J, Green-Thompson R, Ingram C, Crookes RL, Fawcus S, Anthony J, Courtney L, Roubinian N, Jauregui A, Hilton JF, Murphy EL, NHLBI REDS-III South Africa Program. Antenatal blood transfusion in South Africa: indications and practice in a high-HIV-prevalence setting. Transfusion. 2020 03; 60(3):479-487.  View on PubMed
  19. Gottschall J, Wu Y, Triulzi D, Kleinman S, Strauss R, Zimrin AB, McClure C, Tan S, Bialkowski W, Murphy E, Ness P, NHLBI Recipient Epidemiology and Donor Evaluation (REDS-III) Study. The epidemiology of platelet transfusions: an analysis of platelet use at 12 US hospitals. Transfusion. 2020 01; 60(1):46-53.  View on PubMed
  20. Candotti D, Sauvage V, Cappy P, Boullahi MA, Bizimana P, Mbensa GO, Oumar Coulibaly S, Rakoto Alson AO, Soumana H, Tagny-Tayou C, Murphy EL, Laperche S, Francophone Africa Transfusion Research Network. High rate of hepatitis C virus and human immunodeficiency virus false-positive results in serologic screening in sub-Saharan Africa: adverse impact on the blood supply. Transfusion. 2020 01; 60(1):106-116.  View on PubMed

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