Research Funding

  • August 15, 2017 - July 31, 2022 - Research training in HIV-related transfusion medicine and hematology in South Africa , Principal Investigator . Sponsor: NIH, Sponsor Award ID: D43TW010345
  • April 1, 2013 - March 31, 2017 - Recipient Epidemiology and Donor Evaluation Study III (REDS-III) Internat'l Site , Principal Investigator . Sponsor: NIH, Sponsor Award ID: 268201100009I-2-26800002-1
  • March 15, 2013 - March 14, 2017 - Recipient Epidemiology and Donor Evaluation Study III (REDS-III) Domestic Hub , Principal Investigator . Sponsor: NIH, Sponsor Award ID: 268201100005I-2-26800002-1
  • January 5, 2004 - May 31, 2016 - Health Outcomes in Blood Donors and Recipients , Principal Investigator . Sponsor: NIH, Sponsor Award ID: K24HL075036
  • June 1, 2011 - May 31, 2012 - XV International Conference on Human Retrovirology: HTLV and Related Viruses , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R13CA159758
  • April 12, 1999 - January 31, 2010 - Pathophysiology of HTLV-I and HTLV-II Infection , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R01HL062235
  • June 1, 2003 - May 31, 2008 - XI International Conference on Human Retrovirology: HTLV , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R13CA098290
  • September 16, 1994 - September 30, 2003 - RETROVIRUS EPIDEMIOLOGY DONOR STUDY (REDS) BLOOD CENTER , Principal Investigator . Sponsor: NIH/NHLBI, Sponsor Award ID: N01HB047114
  • August 15, 1997 - June 30, 2003 - MEDICAL CONSEQUENSES OF HTLV II IN DRUG ABUSERS , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R01DA011241
  • December 1, 1994 - November 30, 1999 - VIRAL ACTIVATION TRANSFUSION STUDY , Principal Investigator . Sponsor: NIH/NHLBI, Sponsor Award ID: N01HB057121
  • July 17, 1989 - September 15, 1994 - EPIDEMIOLOGIC STUDIES OF HUMAN RETROVIRUSES IN BLOOD , Principal Investigator . Sponsor: NIH/NHLBI, Sponsor Award ID: N01HB097077
  • July 19, 1996 - January 1, 1900 - MOLECULAR EPIDEMIOLOGY OF HTLV-II , Principal Investigator . Sponsor: NIH, Sponsor Award ID: F06TW002148

Education

Massachusetts Institute of Technology, B.S., 1974, Marine Biology
Stanford University, Stanford, CA, M.D., 1980, Medicine
University of California, Berkeley, CA, M.P.H., 1981, Epidemiology

Honors & Awards

  • 1970
    Westinghouse Scholarship
  • 1980-81
    University of California Graduate Scholarship
  • 1984
    Chateaubriand prize of the French Government
  • 1984
    International Agency for Cancer Research Fellowship (declined)
  • 1988
    FDA Commissioners Special Citation
  • 1989-92
    Charles E. Culpeper Scholarship
  • 1995-96
    Fulbright Scholarship, France
  • 1995-96
    NIH Fogarty Senior International Fellowship
  • 2003
    President, International Retrovirology Association

Selected Publications

  1. Swarts A, van den Berg K, Vermeulen M, Jentsch U, Creel D, Swanevelder R, Hemingway-Foday JJ, Murphy EL, Custer B. Risk factors for incident human immunodeficiency virus infection in South African blood donors. View on PubMed
  2. Van Weyenbergh J, Assone T, Racine I, Menezes S, Gonçalves F, Folgosi V, Marcusso R, Haziot M, Smid J, Dahy F, Gascon M, Paiva A, Galvao-Castro B, Araújo T, Grassi M, Sousa M, Puccioni-Sohler M, Nukui Y, Kashima S, Dierckx T, Twizere JC, Murphy E, Bruhn R, Pannecouque C, Claes S, Vanderlinden E, Schols D, Vercauteren J, Alvarez C, Lopez G, Talledo M, Gotuzzo E, Oliveira A, Cleynen I, Casseb J. Multi-cohort cross-omics analysis reveals disease mechanisms and therapeutic targets in HTLV-1-associated myelopathy, a neglected retroviral neuroinflammatory disorder. View on PubMed
  3. Kisanuki YY, Nobrega PR, Himes R, Jayadev S, Bernat JA, Prakash V, Gibson JB, Larson A, Sgobbi P, DeBarber AE, Murphy E, Fedor B, Wong Po Foo C, Dutta R, Imperiale M, Garner W, Quan J, Vig P, Duell PB, Perez S, Ramdhani RA, Saute JA, RESTORE Study Group Collaborators. Efficacy, safety, and tolerability of chenodeoxycholic acid (CDCA) in adult patients with cerebrotendinous xanthomatosis (RESTORE): A randomized withdrawal, double-blind, placebo-controlled, crossover phase-3 study. View on PubMed
  4. Kolaitis NA, Barnes H, Levine DJ, Castillo H, Arcasoy SM, Bacchetta M, Benvenuto L, Berman-Rosenzweig E, Cevasco M, Demarest CT, Dewachter C, Erasmus ME, Glanville AR, Granton J, Keshavjee S, Khangoora V, Krishnan S, Mercier O, Miltiades AN, Montani D, Murphy E, Robbins I, Rahaghi FF, Saddoughi SA, Savale L, Simon MA, Vachiery JL, Ventetuolo CE, Whitford HM, Girgis RE. Approach to Lung Transplantation in Pulmonary Arterial Hypertension: A Delphi Consensus on Behalf of the Transplant Task Force of the Pulmonary Vascular Research Institute. View on PubMed
  5. Cosgrave EJ, Blake M, Murphy E, Sheridan A, Doyle F, Kavanagh P. Is the public ready for a tobacco-free Ireland? A national survey of public knowledge and attitudes to tobacco endgame in Ireland. Tob Control. 2024 Oct 19; 33(6):807-812. View on PubMed
  6. Sheridan A, Conway R, Murphy E, Blake M, Mulcahy M, Howell F, Gordon C, Doyle F, Kavanagh PM. The impact of the introduction of tobacco product plain packaging on consumer responses in Ireland: a real-world policy evaluation stratified by socioeconomic groups. Eur J Public Health. 2024 Oct 01; 34(5):970-978. View on PubMed
  7. Willemse RJ, Grobler CJ, Murphy EL, Roubinian N, Colemen C, Machaba S, Vermeulen M. The prevalence of hepatitis B virus, human T-lymphotropic virus and human immunodeficiency virus in patients receiving blood transfusions in South Africa. Vox Sang. 2024 Nov; 119(11):1166-1173. View on PubMed
  8. Joseph J, Premeaux TA, Tandon R, Murphy EL, Bruhn R, Nicot C, Herrera BB, Lemenze A, Alatrash R, Baffour Tonto P, Ndhlovu LC, Jain P. Dendritic Cells Pulsed with HAM/TSP Exosomes Sensitize CD4 T Cells to Enhance HTLV-1 Infection, Induce Helper T-Cell Polarization, and Decrease Cytotoxic T-Cell Response. Viruses. 2024 Sep 10; 16(9). View on PubMed
  9. van den Berg K, Murphy EL, Maartens G, Louw VJ, Grebe E. The impact of non-disclosure of HIV status and antiretroviral therapy on HIV recency testing and incidence algorithms. Vox Sang. 2024 Jun; 119(6):581-589. View on PubMed
  10. Shichijo T, Yasunaga JI, Sato K, Nosaka K, Toyoda K, Watanabe M, Zhang W, Koyanagi Y, Murphy EL, Bruhn RL, Koh KR, Akari H, Ikeda T, Harris RS, Green PL, Matsuoka M. Vulnerability to APOBEC3G linked to the pathogenicity of deltaretroviruses. Proc Natl Acad Sci U S A. 2024 Mar 26; 121(13):e2309925121. View on PubMed
  11. Jentsch U, Vermeulen M, van den Berg K, Swanevelder R, Creel D, Jacobs G, Hemingway-Foday JJ, Nyoni C, Murphy EL, Custer B. A case-control study of risk factors for incident hepatitis B virus infection in South African blood donors. Int J Infect Dis. 2024 Apr; 141:106958. View on PubMed
  12. Murphy EL. HTLV-1 and blood donation. Br J Haematol. 2024 01; 204(1):29-30. View on PubMed
  13. Jacobs G, Van den Berg K, Vermeulen M, Swanevelder R, Custer B, Murphy EL. Association of ABO and RhD blood groups with the risk of HIV infection. PLoS One. 2023; 18(4):e0284975. View on PubMed
  14. van den Berg K, Murphy EL, Louw VJ, Maartens G, Hughes SD. Motivations for blood donation by HIV-positive individuals on antiretrovirals in South Africa: A qualitative study. Transfus Med. 2023 Aug; 33(4):277-286. View on PubMed
  15. Assone T, Menezes SM, de Toledo Gonçalves F, Folgosi VA, da Silva Prates G, Dierckx T, Braz M, Smid J, Haziot ME, Marcusso RMN, Dahy FE, Vanderlinden E, Claes S, Schols D, Bruhn R, Murphy EL, Penalva de Oliveira AC, Daelemans D, Vercauteren J, Casseb J, Van Weyenbergh J. Systemic cytokines and GlycA discriminate disease status and predict corticosteroid response in HTLV-1-associated neuroinflammation. J Neuroinflammation. 2022 Dec 08; 19(1):293. View on PubMed
  16. van den Berg K, Vermeulen M, Bakkour S, Stone M, Jacobs G, Nyoni C, Barker C, McClure C, Creel D, Grebe E, Roubinian N, Jentsch U, Custer B, Busch MP, Murphy EL. Blood Center Testing Allows the Detection and Rapid Treatment of Acute and Recent HIV Infection. Viruses. 2022 10 23; 14(11). View on PubMed
  17. Vermeulen M, van Schalkwyk C, Jacobs G, van den Berg K, Stone M, Bakkour S, Custer B, Jentsch U, Busch MP, Murphy E, Grebe E. The Impact of Early Antiretroviral Treatment (ART) for HIV on the Sensitivity of the Latest Generation of Blood Screening and Point of Care Assays. Viruses. 2022 06 29; 14(7). View on PubMed
  18. Tagny CT, Ikomey G, Ngo Sack F, Achu C, Ndemanou M, Ninmou C, Gesu C, Essomba G, Fongue Simo A, Nguefack Tsague G, Mbanya D, Murphy E. Implementation of an Africa-specific donor health questionnaire for human immunodeficiency virus risk screening. View on PubMed
  19. Miranda C, Utsch-Gonçalves D, Piassi FCC, Loureiro P, Gomes I, Ribeiro MA, de Almeida-Neto C, Blatyta P, Amorim L, Garcia Mateos SO, Murphy EL, Custer B, Carneiro-Proietti ABF, Sabino EC. Prevalence and Risk Factors for Human T-Cell Lymphotropic Virus (HTLV) in Blood Donors in Brazil-A 10-Year Study (2007-2016). Front Med (Lausanne). 2022; 9:844265. View on PubMed
  20. Kim D, Myllymäki M, Kankainen M, Jarvinen T, Park G, Bruhn R, Murphy EL, Mustjoki S. Somatic STAT3 mutations in CD8+ T cells of healthy blood donors carrying human T-cell leukemia virus type 2. Haematologica. 2022 02 01; 107(2):550-554. View on PubMed

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