August 15, 2017 - July 31, 2022 - Research training in HIV-related transfusion medicine and hematology in South Africa , Principal Investigator . Sponsor: NIH, Sponsor Award ID: D43TW010345
April 1, 2013 - March 31, 2017 - Recipient Epidemiology and Donor Evaluation Study III (REDS-III) Internat'l Site , Principal Investigator . Sponsor: NIH, Sponsor Award ID: 268201100009I-2-26800002-1
March 15, 2013 - March 14, 2017 - Recipient Epidemiology and Donor Evaluation Study III (REDS-III) Domestic Hub , Principal Investigator . Sponsor: NIH, Sponsor Award ID: 268201100005I-2-26800002-1
January 5, 2004 - May 31, 2016 - Health Outcomes in Blood Donors and Recipients , Principal Investigator . Sponsor: NIH, Sponsor Award ID: K24HL075036
Education
Massachusetts Institute of Technology, B.S., 1974, Marine Biology Stanford University, Stanford, CA, M.D., 1980, Medicine University of California, Berkeley, CA, M.P.H., 1981, Epidemiology
Honors & Awards
1970 Westinghouse Scholarship
1980-81 University of California Graduate Scholarship
1984 Chateaubriand prize of the French Government
1984 International Agency for Cancer Research Fellowship (declined)
1988 FDA Commissioners Special Citation
1989-92 Charles E. Culpeper Scholarship
1995-96 Fulbright Scholarship, France
1995-96 NIH Fogarty Senior International Fellowship
2003 President, International Retrovirology Association
Selected Publications
Murphy EL. HTLV-1 and blood donation. Br J Haematol. 2023 Aug 14.
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Jacobs G, Van den Berg K, Vermeulen M, Swanevelder R, Custer B, Murphy EL. Association of ABO and RhD blood groups with the risk of HIV infection. PLoS One. 2023; 18(4):e0284975.
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Assone T, Menezes SM, de Toledo Gonçalves F, Folgosi VA, da Silva Prates G, Dierckx T, Braz M, Smid J, Haziot ME, Marcusso RMN, Dahy FE, Vanderlinden E, Claes S, Schols D, Bruhn R, Murphy EL, Penalva de Oliveira AC, Daelemans D, Vercauteren J, Casseb J, Van Weyenbergh J. Systemic cytokines and GlycA discriminate disease status and predict corticosteroid response in HTLV-1-associated neuroinflammation. J Neuroinflammation. 2022 Dec 08; 19(1):293.
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van den Berg K, Vermeulen M, Bakkour S, Stone M, Jacobs G, Nyoni C, Barker C, McClure C, Creel D, Grebe E, Roubinian N, Jentsch U, Custer B, Busch MP, Murphy EL. Blood Center Testing Allows the Detection and Rapid Treatment of Acute and Recent HIV Infection. Viruses. 2022 10 23; 14(11).
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Vermeulen M, van Schalkwyk C, Jacobs G, van den Berg K, Stone M, Bakkour S, Custer B, Jentsch U, Busch MP, Murphy E, Grebe E. The Impact of Early Antiretroviral Treatment (ART) for HIV on the Sensitivity of the Latest Generation of Blood Screening and Point of Care Assays. Viruses. 2022 06 29; 14(7).
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Miranda C, Utsch-Gonçalves D, Piassi FCC, Loureiro P, Gomes I, Ribeiro MA, de Almeida-Neto C, Blatyta P, Amorim L, Garcia Mateos SO, Murphy EL, Custer B, Carneiro-Proietti ABF, Sabino EC. Prevalence and Risk Factors for Human T-Cell Lymphotropic Virus (HTLV) in Blood Donors in Brazil-A 10-Year Study (2007-2016). Front Med (Lausanne). 2022; 9:844265.
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Kim D, Myllymäki M, Kankainen M, Jarvinen T, Park G, Bruhn R, Murphy EL, Mustjoki S. Somatic STAT3 mutations in CD8+ T cells of healthy blood donors carrying human T-cell leukemia virus type 2. Haematologica. 2022 02 01; 107(2):550-554.
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Valencia A, Vergara C, Thio CL, Vince N, Douillard V, Grifoni A, Cox AL, Johnson EO, Kral AH, Goedert JJ, Mangia A, Piazzolla V, Mehta SH, Kirk GD, Kim AY, Lauer GM, Chung RT, Price JC, Khakoo SI, Alric L, Cramp ME, Donfield SM, Edlin BR, Busch MP, Alexander G, Rosen HR, Murphy EL, Wojcik GL, Carrington M, Gourraud PA, Sette A, Thomas DL, Duggal P. Trans-ancestral fine-mapping of MHC reveals key amino acids associated with spontaneous clearance of hepatitis C in HLA-DQβ1. Am J Hum Genet. 2022 02 03; 109(2):299-310.
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Marqué L, Liehl P, De Boer J, Pottel H, Murphy EL, Bruhn R, Stone M, Kaidarova Z, Lee TH, Busch M, Zrein M. A novel high performing multiplex immunoassay Multi-HTLV for serological confirmation and typing of HTLV infections. PLoS Negl Trop Dis. 2021 11; 15(11):e0009925.
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Rapodile T, Mitchel J, Swanevelder R, Murphy EL, van den Berg K. Re-engineering the medical assessment of blood donors in South Africa: The balance between supply and safety. Transfusion. 2021 12; 61(12):3361-3371.
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van den Berg K, Vermeulen M, Louw VJ, Murphy EL, Maartens G. Undisclosed HIV status and antiretroviral therapy use among South African blood donors. Transfusion. 2021 08; 61(8):2392-2400.
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Vermeulen M, Swanevelder R, Van Zyl G, Lelie N, Murphy EL. An assessment of hepatitis B virus prevalence in South African young blood donors born after the implementation of the infant hepatitis B virus immunization program: Implications for transfusion safety. Transfusion. 2021 09; 61(9):2688-2700.
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Vergara C, Valencia A, Thio CL, Goedert JJ, Mangia A, Piazzolla V, Johnson E, Kral AH, O'Brien TR, Mehta SH, Kirk GD, Kim AY, Lauer GM, Chung RT, Cox AL, Peters MG, Khakoo SI, Alric L, Cramp ME, Donfield SM, Edlin BR, Busch MP, Alexander G, Rosen HR, Murphy EL, Wojcik GL, Taub MA, Thomas DL, Duggal P. A Multiancestry Sex-Stratified Genome-Wide Association Study of Spontaneous Clearance of Hepatitis C Virus. J Infect Dis. 2021 06 15; 223(12):2090-2098.
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Samje M, Fondoh VN, Nguefack-Tsague G, Kamalieuk LKJ, Mbanya D, Murphy EL, Tagny CT. Trends in serological markers of transfusion transmissible infections in blood donations at the Bamenda Hospital-based Blood Service, Cameroon. Transfus Clin Biol. 2021 Aug; 28(3):228-233.
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Clements DM, Crumley B, Chew GM, Davis E, Bruhn R, Murphy EL, Ndhlovu LC, Jain P. Phenotypic and Functional Analyses Guiding Combination Immune Checkpoint Immunotherapeutic Strategies in HTLV-1 Infection. Front Immunol. 2021; 12:608890.
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Vergara C, Duggal P, Thio CL, Valencia A, O'Brien TR, Latanich R, Timp W, Johnson EO, Kral AH, Mangia A, Goedert JJ, Piazzola V, Mehta SH, Kirk GD, Peters MG, Donfield SM, Edlin BR, Busch MP, Alexander G, Murphy EL, Kim AY, Lauer GM, Chung RT, Cramp ME, Cox AL, Khakoo SI, Rosen HR, Alric L, Wheelan SJ, Wojcik GL, Thomas DL, Taub MA. Correction: Multi-ancestry fine mapping of interferon lambda and the outcome of acute hepatitis C virus infection. Genes Immun. 2020 Dec; 21(6-8):420.
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Vergara C, Duggal P, Thio CL, Valencia A, O'Brien TR, Latanich R, Timp W, Johnson EO, Kral AH, Mangia A, Goedert JJ, Piazzola V, Mehta SH, Kirk GD, Peters MG, Donfield SM, Edlin BR, Busch MP, Alexander G, Murphy EL, Kim AY, Lauer GM, Chung RT, Cramp ME, Cox AL, Khakoo SI, Rosen HR, Alric L, Wheelan SJ, Wojcik GL, Thomas DL, Taub MA. Multi-ancestry fine mapping of interferon lambda and the outcome of acute hepatitis C virus infection. Genes Immun. 2020 11; 21(5):348-359.
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Roubinian NH, Chowdhury D, Hendrickson JE, Triulzi DJ, Gottschall JL, Looney MR, Matthay MA, Kor DJ, Brambilla D, Kleinman SH, Murphy EL, NHLBI Recipient Epidemiology and Donor Evaluation Study-III (REDS-III). NT-proBNP levels in the identification and classification of pulmonary transfusion reactions. Transfusion. 2020 11; 60(11):2548-2556.
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Vermeulen M, Chowdhury D, Swanevelder R, Grebe E, Brambilla D, Jentsch U, Busch M, Van Zyl G, Murphy EL, REDS-III International Program South Africa. HIV incidence in South African blood donors from 2012 to 2016: a comparison of estimation methods. Vox Sang. 2021 Jan; 116(1):71-80.
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Estrada FGMD, Oliveira CDL, Sabino EC, Custer B, Gonçalez TT, Murphy EL, Teles D, Mendrone-Junior A, Witkin SS, de Almeida-Neto C. Are different motivations and social capital score associated with return behaviour among Brazilian voluntary non-remunerated blood donors? Transfus Med. 2020 Aug; 30(4):255-262.
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