Research Summary

Dr. O'Donnell is a Professor of Clinical Orthopaedic Surgery at the University of California, San Francisco. Dr. O'Donnell is Founder of the Orthopaedic Surgical Osseointegration Society (OSOS). He is Director of both the UCSF Musculoskeletal Research Consortium (METRiCS) and the UCSF international Center for Osseointegration Research, Education, and Surgery (iCORES). He served as Chief of the Orthopaedic Oncology Service in the UCSF Department of Orthopaedic Surgery from 2002 through 2019. He also served as Director of the Sarcoma Program at the UCSF Helen Diller Family Comprehensive Cancer Center through 2023. He was an Extramural Member of the Steering Committee for the Department of Defense Osseointegration Program and he is proud to have served under the auspices of the American Red Cross at the Walter Reed National Military Medical Center. He was also appointed as Visiting Professor of Surgery at the Harvard Medical School.


Fellowship, 1996 - Musculoskeletal Oncology, University of Washington
Residency, 1995 - Orthopaedic Surgery, Harvard Combined Orthopaedic Program
M.D., 1989 - Medicine, Harvard Medical School
A.B., 1985 - Biology, Harvard College

Honors & Awards

  • Best Paper Award, Musculoskeletal Tumor Society Annual Meeting, 2018
  • Top Doctors, Marin Magazine, 2017-2020
  • Top Doctors, San Francisco Magazine, 2017-2020
  • Bishop's Distinguished Catholic Alumni Award, Diocese of Allentown, Pennsylvania, 2017

Selected Publications

  1. O'Donnell RJ,
    DuBois SG,
    Haas-Kogan DA,
    Braunstein SE,
    Hameed M. Sarcomas of bone. DeVita, Hellman and Rosenberg's Cancer: Principles & Practice of Oncology Edited by Vincent T. DeVita, Jr., Theodore S. Lawrence, and Steven A. Rosenberg. 2023; 1141-1176.  View on PubMed
  2. Tanaka KS, Andaya VR, Thorpe SW, Gundle KR, Hayden JB, Duong YC, Avedian RS, Mohler DG, Morse LJ, Zimel MN, O'Donnell RJ, Fang A, Randall RL, Tran TH, New C, Wustrack RL, other members of Study Group FORCE. Survival and failure modes of the Compress® spindle and expandable distal femur endoprosthesis among pediatric patients: A multi-institutional study. J Surg Oncol. 2023 Jan; 127(1):148-158.  View on PubMed
  3. Prophylactic Antibiotic Regimens in Tumor Surgery (PARITY) Investigators, Ghert M, Schneider P, Guyatt G, Thabane L, Vélez R, O'Shea T, Randall RL, Turcotte R, Wilson D, Wunder JS, Baptista AM, Cheng EY, Doung YC, Ferguson PC, Giglio V, Hayden J, Heels-Ansdell D, Khan SA, Sampath Kumar V, McKay P, Miller B, van de Sande M, Zumárraga JP, Bhandari M. Comparison of Prophylactic Intravenous Antibiotic Regimens After Endoprosthetic Reconstruction for Lower Extremity Bone Tumors: A Randomized Clinical Trial. JAMA Oncol. 2022 Mar 01; 8(3):345-353.  View on PubMed
  4. STARSurg Collaborative and COVIDSurg Collaborative
    . Death following pulmonary complications of surgery before and during the SARS-CoV-2 pandemic. Br J Surg. 2021 Dec 01; 108(12):1448-1464.  View on PubMed
  5. COVIDSurg Collaborative. Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study. Lancet Oncol. 2021 Nov; 22(11):1507-1517.  View on PubMed
  6. COVIDSurg Collaborative, GlobalSurg Collaborative . SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study. Br J Surg. 2021 Sep 27; 108(9):1056-1063.  View on PubMed
  7. Glasbey, J.
    COVIDSurg Collaborative. Resilience of elective cancer surgery systems during COVID-19 lockdowns: International, prospective cohort study of planned surgery for 15 tumour types in 61 countries. Annals of Oncology. 2021; 32(S5):S1132-S1133.  View on PubMed
  8. COVIDSurg Collaborative, GlobalSurg Collaborative. SARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study. Anaesthesia. 2022 Jan; 77(1):28-39.  View on PubMed
  9. COVIDSurg Collaborative, GlobalSurg Collaborative. Effects of pre-operative isolation on postoperative pulmonary complications after elective surgery: an international prospective cohort study. Anaesthesia. 2021 11; 76(11):1454-1464.  View on PubMed
  10. Schneider P, Heels-Ansdell D, Thabane L, Ghert M, PARITY Investigators. Prophylactic Antibiotic Regimens In Tumor Surgery (PARITY): a multi-center randomized controlled study comparing alternative antibiotic regimens in patients undergoing tumor resections with endoprosthetic replacements-a statistical analysis plan. Trials. 2021 Mar 22; 22(1):223.  View on PubMed
  11. COVIDSurg Collaborative, GlobalSurg Collaborative. Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study. Anaesthesia. 2021 06; 76(6):748-758.  View on PubMed
  12. COVIDSurg Collaborative . Preoperative nasopharyngeal swab testing and postoperative pulmonary complications in patients undergoing elective surgery during the SARS-CoV-2 pandemic. Br J Surg. 2021 01 27; 108(1):88-96.  View on PubMed
  13. Chen WS,
    Lometti M,
    Wustrack RL,
    Zimel MN,
    O'Donnell RJ,
    Horvai AE,
    Cho SJ,
    Okimoto RA,
    Jahan TM,
    Gottschalk AR,
    Braunstein SE. Intraoperative radiotherapy without external beam radiotherapy in the management of primary soft tissue sarcomas of the extremities. Intl J Rad Biol Physics. 2020; 108(3):e5.  View on PubMed
  14. Chew J,
    Lloyd SA,
    Okimoto RA,
    Sabnis A,
    Nakakura E,
    Corvera C,
    Zimel MN,
    Horvai AE,
    Cho SJ,
    Wustrack RL,
    Gottschalk AR,
    O'Donnell RJ,
    Jahan TM,
    Braunstein SE. Outcomes of elderly patients with soft tissue sarcoma of the extremities. Intl J Rad Onc Biol Physics. 2020; 108(3):e6.  View on PubMed
  15. Glasbey JC, Nepogodiev D, Simoes JFF, Omar O, Li E, Venn ML, Abou Chaar MK, Capizzi V, Chaudhry D, Desai A, Edwards JG, Evans JP, Fiore M, Videria JF, Ford SJ, Ganly I, Griffiths EA, Gujjuri RR, Kolias AG, Kaafarani HMA, Minaya-Bravo A, McKay SC, Mohan HM, Roberts KJ, San Miguel-Méndez C, Pockney P, Shaw R, Smart NJ, Stewart GD, Sundar Mrcog S, Vidya R, Bhangu AA, COVIDSurg Collaborative. Elective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study. J Clin Oncol. 2021 01 01; 39(1):66-78.  View on PubMed
  16. McGill K, Motamedi D, Azimi N, Horvai A, O'Donnell R. Pleomorphic Sarcoma in a Patient with Osteopetrosis. J Radiol Case Rep. 2020 Jul; 14(7):1-9.  View on PubMed
  17. Butte Z, Tanaka K, Andaya V, Zimel M, O'Donnell RJ, Wustrack R. Risk of endoprosthetic infection and impact of health-related quality of life in patients with osteosarcoma and giant cell tumor of bone; a retrospective case-control study. Annals of Joint. 2020; 5(27):1-10.  View on PubMed
  18. Gutierrez LB, Link TM, Horvai AE, Joseph GB, O'Donnell RJ, Motamedi D. Secondary aneurysmal bone cysts and associated primary lesions: imaging features of 49 cases. Clin Imaging. 2020 Jun; 62:23-32.  View on PubMed
  19. Zaid MB, O'Donnell RJ, Potter BK, Forsberg JA. Orthopaedic Osseointegration: State of the Art. J Am Acad Orthop Surg. 2019 Nov 15; 27(22):e977-e985.  View on PubMed
  20. Strony J, Brown S, Choong P, Ghert M, Jeys L, O'Donnell RJ. Musculoskeletal Infection in Orthopaedic Oncology: Assessment of the 2018 International Consensus Meeting on Musculoskeletal Infection. J Bone Joint Surg Am. 2019 Oct 16; 101(20):e107.  View on PubMed

Go to UCSF Profiles, powered by CTSI