Research Funding

  • August 27, 2007 - August 31, 2022 - HARC Center: HIV Accessory and Regulatory Complexes , Co-Investigator . Sponsor: NIH, Sponsor Award ID: P50GM082250
  • February 1, 2016 - January 31, 2021 - TAT Transactivation , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R01AI125104
  • July 8, 2011 - June 30, 2016 - Martin Delaney Collaboratory to Eradicate HIV-1 Infection , Co-Investigator . Sponsor: NIH, Sponsor Award ID: U19AI096113
  • January 1, 2001 - November 30, 2015 - TAT Transactivation , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R01AI049104
  • September 30, 2004 - January 31, 2010 - Molecular Mechanisms of HIV Post-Integration Latency , Co-Investigator . Sponsor: NIH, Sponsor Award ID: P01AI058708
  • July 1, 2003 - December 31, 2007 - CIITA and MHC II Transcription , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R01AI050770
  • January 1, 2002 - December 30, 2006 - Mechanism of HIV 1 Nef Action , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R01AI051165
  • May 1, 1996 - April 30, 1997 - CONFERENCE OF MOLECULAR BIOLOGY OF HIV , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R13AI039463
  • July 1, 1990 - June 30, 1995 - BLS II--DEFECTIVE PROTEINS AND GENES , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R01AI029954
  • September 15, 1977 - December 31, 1988 - U.C.S.F. MULTIPURPOSE ARTHRITIS CENTER , Co-Investigator . Sponsor: NIH, Sponsor Award ID: P60AM020684
  • December 1, 1983 - November 30, 1986 - INTESTINAL IMMUNE RESPONSE: REGULATION AND MECHANISMS , Co-Investigator . Sponsor: NIH, Sponsor Award ID: P01AM033004

Education

Duke University, Durham, NC, B.S, 1968, Chemistry
Harvard Medical School, Boston, MA, M.D., 1973, Medicine

Honors & Awards

  • 1972-1973
    CoSTEP, USPHS, Harvard Medical School, Boston, MA
  • 1978-1980
    Leukemia Society Fellow, Stanford U., Stanford, CA
  • 1980-1981
    American Cancer Society Senior Fellow, Stanford U., Stanford, CA
  • 1981-1982
    Rosalind Russell Scholar, UCSF, SF, CA
  • 1995-present
    Alexander von Humboldt Prize, Bonn, Germany
  • 1998-present
    Honorary Professor, U. Ljubljana, Slovenia

Selected Publications

  1. Huang F, Nguyen TT, Echeverria I, Rakesh R, Cary DC, Paculova H, Sali A, Weiss A, Peterlin BM, Fujinaga K. Reversible phosphorylation of cyclin T1 promotes assembly and stability of P-TEFb. Elife. 2021 11 25; 10.  View on PubMed
  2. Huang F, Shao W, Fujinaga K, Peterlin BM Bromodomain-containing protein 4-independent transcriptional activation by autoimmune regulator (AIRE) and NF-κB.  View on PubMed
  3. Ferdin J, Goricar K, Dolžan V, Plemenitaš A, Martin JN, Peterlin BM, Deeks SG, Lenassi M. Viral protein Nef is detected in plasma of half of HIV-infected adults with undetectable plasma HIV RNA. PLoS One. 2018; 13(1):e0191613.  View on PubMed
  4. Pužar Dominkuš P, Ferdin J, Plemenitaš A, Peterlin BM, Lenassi M. Nef is secreted in exosomes from Nef.GFP-expressing and HIV-1-infected human astrocytes. J Neurovirol. 2017 10; 23(5):713-724.  View on PubMed
  5. Sabino Cunha M, Lima Sampaio T, Peterlin BM, Jesus da Costa L A Truncated Nef Peptide from SIVcpz Inhibits the Production of HIV-1 Infectious Progeny.  View on PubMed
  6. Shao W, Zumer K, Fujinaga K, Peterlin BM FBXO3 Protein Promotes Ubiquitylation and Transcriptional Activity of AIRE (Autoimmune Regulator).  View on PubMed
  7. Pak V, Eifler TT, Jäger S, Krogan NJ, Fujinaga K, Peterlin BM. CDK11 in TREX/THOC Regulates HIV mRNA 3' End Processing. Cell Host Microbe. 2015 Nov 11; 18(5):560-70.  View on PubMed
  8. Fujinaga K, Luo Z, Schaufele F, Peterlin BM Visualization of positive transcription elongation factor b (P-TEFb) activation in living cells.  View on PubMed
  9. Eifler TT, Shao W, Bartholomeeusen K, Fujinaga K, Jäger S, Johnson JR, Luo Z, Krogan NJ, Peterlin BM. Cyclin-dependent kinase 12 increases 3' end processing of growth factor-induced c-FOS transcripts. Mol Cell Biol. 2015 Jan; 35(2):468-78.  View on PubMed
  10. Pandeló José D, Bartholomeeusen K, da Cunha RD, Abreu CM, Glinski J, da Costa TB, Bacchi Rabay AF, Pianowski Filho LF, Dudycz LW, Ranga U, Peterlin BM, Pianowski LF, Tanuri A, Aguiar RS. Reactivation of latent HIV-1 by new semi-synthetic ingenol esters. Virology. 2014 Aug; 462-463:328-39.  View on PubMed
  11. Bartholomeeusen K, Fujinaga K, Xiang Y, Peterlin BM Histone deacetylase inhibitors (HDACis) that release the positive transcription elongation factor b (P-TEFb) from its inhibitory complex also activate HIV transcription.  View on PubMed
  12. Stanley DJ, Bartholomeeusen K, Crosby DC, Kim DY, Kwon E, Yen L, Cartozo NC, Li M, Jäger S, Mason-Herr J, Hayashi F, Yokoyama S, Krogan NJ, Harris RS, Peterlin BM, Gross JD. Inhibition of a NEDD8 Cascade Restores Restriction of HIV by APOBEC3G. PLoS Pathog. 2012 Dec; 8(12):e1003085.  View on PubMed
  13. Peterlin BM, Brogie JE, Price DH. 7SK snRNA: a noncoding RNA that plays a major role in regulating eukaryotic transcription. Wiley Interdiscip Rev RNA. 2012 Jan-Feb; 3(1):92-103.  View on PubMed
  14. Peterlin BM. Transcription elongation takes central stage: the P-TEFb connection. Cell Cycle. 2010 Aug 01; 9(15):2933-4.  View on PubMed
  15. Peterlin BM, Price DH. Controlling the elongation phase of transcription with P-TEFb. Mol Cell. 2006 Aug 04; 23(3):297-305.  View on PubMed

Go to UCSF Profiles, powered by CTSI