University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Steve E. Braunstein, MD, PhD

Steve E. Braunstein, MD, PhD

Assistant Professor, Associate Program Director, Dept. of Radiation Oncology, UCSF

Cancer Center Program Memberships

Neurologic Oncology

Research Summary

Dr. Braunstein is a radiation oncologist with a clinical interest in the treatment of pediatric, central nervous system, and soft tissue malignancies. He has expertise in modern radiation therapy techniques including stereotactic radiotherapy (Gamma Knife, Cyberknife, Linac-based SBRT), intraoperative radiotherapy, and intensity modulated radiation therapy.

Dr. Braunstein earned his M.D. at New York University School of Medicine where he also obtained a Ph.D. studying essential molecular pathways by which cancer cells mediate response to radiation. He completed residency at UCSF in 2014, during which time he continued to study cancer cell response to radiation, investigating genetic polymorphisms which yield the observed heterogeneity of tumor cell population radiosensitivity and risk of radiation-related secondary cancer.

Education

University of California, San Francisco, 06/14, Radiation Oncology
Brighman and Women's Hospital, 06/10, Internal Medicine
New York University School of Medicine, M.D., Ph.D., 06/09


Professional Experience

  • 2014-present
    Assistant Professor, Radiation Oncology, UCSF
  • 2010-2014
    Resident, Radiation Oncology, UCSF
  • 2015-present
    Associate Program Director, Department of Radiation Oncology, UCSF

Honors & Awards

  • 2014
    RSNA Resident Research Award, Radiological Society of North America
  • 2014
    UCSF Patient Care Fund Award, UCSF
  • 2014
    Mount Zion Fund Research Travel Award, UCSF
  • 2013
    UCSF Exceptional Physician Award, UCSF
  • 2013
    UCSF Resident QI Champion, UCSF
  • 2012
    UCSF Patient Care Fund Award, UCSF
  • 2008
    AOA Inductee, NYUSOM
  • 2008
    Honors in Doctoral Dissertation, NYUSOM
  • 2003
    NYC Urban Health Initiative Award, NYC Department of Public Health

Selected Publications

  1. McTyre ER, Soike MH, Farris M, Ayala-Peacock DN, Hepel JT, Page BR, Shen C, Kleinberg L, Contessa JN, Corso C, Chiang V, Henson-Masters A, Cramer CK, Ruiz J, Pasche B, Watabe K, D'Agostino R, Su J, Laxton AW, Tatter SB, Fiveash JB, Ahluwalia M, Kotecha R, Chao ST, Braunstein SE, Attia A, Chung C, Chan MD. Multi-institutional validation of brain metastasis velocity, a recently defined predictor of outcomes following stereotactic radiosurgery. Radiother Oncol. 2019 Sep 13.
    View on PubMed
  2. Sloan EA, Cooney T, Oberheim Bush NA, Buerki R, Taylor J, Clarke JL, Torkildson J, Kline C, Reddy A, Mueller S, Banerjee A, Butowski N, Chang S, Mummaneni PV, Chou D, Tan L, Theodosopoulos P, McDermott M, Berger M, Raffel C, Gupta N, Sun PP, Li Y, Shah V, Cha S, Braunstein S, Raleigh DR, Samuel D, Scharnhorst D, Fata C, Guo H, Moes G, Kim JYH, Koschmann C, Van Ziffle J, Onodera C, Devine P, Grenert JP, Lee JC, Pekmezci M, Phillips JJ, Tihan T, Bollen AW, Perry A, Solomon DA. Recurrent non-canonical histone H3 mutations in spinal cord diffuse gliomas. Acta Neuropathol. 2019 Sep 12.
    View on PubMed
  3. Jordan K, Morin O, Wahl M, Amirbekian B, Chapman C, Owen J, Mukherjee P, Braunstein S, Henry R. An Open-Source Tool for Anisotropic Radiation Therapy Planning in Neuro-oncology Using DW-MRI Tractography. Front Oncol. 2019; 9:810.
    View on PubMed
  4. Devine CA, Liu KX, Ioakeim-Ioannidou M, Susko M, Poussaint TY, Huisman TAGM, Aboian M, Brown D, Zaslowe-Dude C, Rao AD, Orlina LT, Rawal B, Mueller S, Marcus KJ, Terezakis SA, Braunstein SE, Haas-Kogan DA. Brainstem injury in pediatric patients receiving posterior fossa photon radiation. Int J Radiat Oncol Biol Phys. 2019 Aug 28.
    View on PubMed
  5. Morin O, Chen WC, Nassiri F, Susko M, Magill ST, Vasudevan HN, Wu A, Vallières M, Gennatas ED, Valdes G, Pekmezci M, Alcaide-Leon P, Choudhury A, Interian Y, Mortezavi S, Turgutlu K, Bush NAO, Solberg TD, Braunstein SE, Sneed PK, Perry A, Zadeh G, McDermott MW, Villanueva-Meyer JE, Raleigh DR. Integrated models incorporating radiologic and radiomic features predict meningioma grade, local failure, and overall survival. Neurooncol Adv. 2019 May-Dec; 1(1):vdz011.
    View on PubMed
  6. Sperduto PW, Fang P, Li J, Breen W, Brown PD, Cagney D, Aizer A, Yu JB, Chiang V, Jain S, Gaspar LE, Myrehaug S, Sahgal A, Braunstein S, Sneed P, Cameron B, Attia A, Molitoris J, Wu CC, Wang TJC, Lockney NA, Beal K, Parkhurst J, Buatti JM, Shanley R, Lou E, Tandberg DD, Kirkpatrick JP, Shi D, Shih HA, Chuong M, Saito H, Aoyama H, Masucci L, Roberge D, Mehta MP. Estimating survival in patients with gastrointestinal cancers and brain metastases: An update of the graded prognostic assessment for gastrointestinal cancers (GI-GPA). Clin Transl Radiat Oncol. 2019 Sep; 18:39-45.
    View on PubMed
  7. McDermott MW, Sheehan J, Braunstein S. Introduction. Radiosurgery and radiotherapy for meningiomas: overview of the issue. Neurosurg Focus. 2019 Jun 01; 46(6):E1.
    View on PubMed
  8. Singer L, Braunstein S, Klopp A, Joyner M. Development and Implementation of a Simulation-Based Educational Workshop on Gynecological Brachytherapy: Pilot Study at a National Meeting. Pract Radiat Oncol. 2019 Sep - Oct; 9(5):e465-e472.
    View on PubMed
  9. Chapman CH, Hara JH, Molinaro AM, Clarke JL, Oberheim Bush NA, Taylor JW, Butowski NA, Chang SM, Fogh SE, Sneed PK, Nakamura JL, Raleigh DR, Braunstein SE. Reirradiation of recurrent high-grade glioma and development of prognostic scores for progression and survival. Neurooncol Pract. 2019 Sep; 6(5):364-374.
    View on PubMed
  10. Braunstein SE, London WB, Kreissman SG, Villablanca JG, Davidoff AM, DeSantes K, Castleberry RP, Murray K, Diller L, Matthay K, Cohn SL, Shulkin B, von Allmen D, Parisi MT, Van Ryn C, Park JR, La Quaglia MP, Haas-Kogan DA. Role of the extent of prophylactic regional lymph node radiotherapy on survival in high-risk neuroblastoma: A report from the COG A3973 study. Pediatr Blood Cancer. 2019 Jul; 66(7):e27736.
    View on PubMed
  11. Hughes RT, Masters AH, McTyre ER, Farris MK, Chung C, Page BR, Kleinberg LR, Hepel J, Contessa JN, Chiang V, Ruiz J, Watabe K, Su J, Fiveash JB, Braunstein S, Chao S, Attia A, Ayala-Peacock DN, Chan MD. Initial SRS for Patients With 5 to 15 Brain Metastases: Results of a Multi-Institutional Experience. Int J Radiat Oncol Biol Phys. 2019 Aug 01; 104(5):1091-1098.
    View on PubMed
  12. Xu MJ, Su D, Deboer R, Garcia M, Tahir P, Anderson W, Kinderman A, Braunstein S, Sherertz T. Palliative Oncologic Care Curricula for Providers in Resource-Limited and Underserved Communities: a Systematic Review. J Cancer Educ. 2019 Apr; 34(2):205-215.
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  13. Singer L, Sharee K, Boreta L, Silveira WR, Braunstein S, Fogh S. Quality Improvement Initiative to Improve Tobacco Cessation Efforts in Radiation Oncology. J Oncol Pract. 2019 Apr; 15(4):e382-e388.
    View on PubMed
  14. Wu SY, Singer L, Boreta L, Garcia MA, Fogh SE, Braunstein SE. Palliative radiotherapy near the end of life. BMC Palliat Care. 2019 Mar 23; 18(1):29.
    View on PubMed
  15. Susko M, Yu Y, Ma L, Nakamura J, Fogh S, Raleigh DR, Golden E, Theodosopoulos PV, McDermott MW, Sneed PK, Braunstein SE. Preoperative Dural Contact and Recurrence Risk After Surgical Cavity Stereotactic Radiosurgery for Brain Metastases: New Evidence in Support of Consensus Guidelines. Adv Radiat Oncol. 2019 Jul-Sep; 4(3):458-465.
    View on PubMed
  16. Sperduto PW, Fang P, Li J, Breen W, Brown PD, Cagney D, Aizer A, Yu J, Chiang V, Jain S, Gaspar LE, Myrehaug S, Sahgal A, Braunstein S, Sneed P, Cameron B, Attia A, Molitoris J, Wu CC, Wang TJC, Lockney N, Beal K, Parkhurst J, Buatti JM, Shanley R, Lou E, Tandberg DD, Kirkpatrick JP, Shi D, Shih HA, Chuong M, Saito H, Aoyama H, Masucci L, Roberge D, Mehta MP. Survival and prognostic factors in patients with gastrointestinal cancers and brain metastases: have we made progress? Transl Res. 2019 06; 208:63-72.
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  17. Burke JF, Sudhakar V, Braunstein S, McDermott M. In Situ Cranioplasty for Renal Cell Skull Metastasis: Technical Note. Cureus. 2019 Feb 24; 11(2):e4128.
    View on PubMed
  18. Braunstein S, Wang L, Newhauser W, Tenenholz T, Rong Y, van der Kogel A, Dominello M, Joiner MC, Burmeister J. Three discipline collaborative radiation therapy (3DCRT) special debate: The United States should build additional proton therapy facilities. J Appl Clin Med Phys. 2019 02; 20(2):7-12.
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  19. Neeley BC, Golden DW, Brower JV, Braunstein SE, Hirsch AE, Mattes MD. Student Perspectives on Oncology Curricula at United States Medical Schools. J Cancer Educ. 2019 Feb; 34(1):56-58.
    View on PubMed
  20. FitzGerald TJ, Donaldson SS, Wharam M, Laurie F, Bishop-Jodoin M, Moni J, Tarbell N, Shulkin B, McCarville E, Merchant T, Krasin M, Wolden S, Halperin E, Constine LS, Haas-Kogan D, Marcus K, Freeman C, Wilson JF, Hoppe R, Cox J, Terezakis S, Million L, Smith MA, Mendenhall NP, Marcus RB, Cherlow J, Kalapurakal J, Breneman J, Yock T, MacDonald S, Laack N, Donahue B, Indelicato D, Michalski J, Perkins S, Kachnic L, Choy H, Braunstein S, Esiashvilli N, Roberts KB. Larry Emanuel Kun, March 10, 1946-May 27, 2018. Int J Radiat Oncol Biol Phys. 2019 Jan 01; 103(1):8-14.
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